Arteether
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- CAS-Nr.
- 75887-54-6
- Englisch Name:
- Arteether
- Synonyma:
- SM-22;SM-227;Areether;Arteethe;Arteether;Artemotil;ARPRINOCID;NSC 665971;aArteether;Beta-Arteether
- CBNumber:
- CB11012009
- Summenformel:
- C17H28O5
- Molgewicht:
- 312.4
- MOL-Datei:
- 75887-54-6.mol
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Arteether Eigenschaften
- Schmelzpunkt:
- 80-820C
- alpha
- D21 +154.5° (c = 1.0 in CHCl3)
- Siedepunkt:
- 372.4±42.0 °C(Predicted)
- Dichte
- 1.16±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,2-8°C
- Löslichkeit
- Chloroform (Slightly), Ethyl Acetate (Slightly)
- Aggregatzustand
- Solid
- Farbe
- White
- CAS Datenbank
- 75887-54-6
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
 
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| Alarmwort |
Achtung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H226 |
Flüssigkeit und Dampf entzündbar. |
Entzündbare Flüssigkeiten |
Kategorie 3 |
Warnung |
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| Sicherheit |
| P210 |
Von Hitze, heißen Oberflächen, Funken, offenen Flammen und anderen Zündquellenarten fernhalten. Nicht rauchen. |
| P233 |
Behälter dicht verschlossen halten. |
| P240 |
Behälter und zu befüllende Anlage erden. |
| P241 |
Explosionsgeschützte [elektrische/Lüftungs-/ Beleuchtungs-/...] Geräte verwenden. |
| P242 |
Nur funkenfreies Werkzeug verwenden. |
| P243 |
Maßnahmen gegen elektrostatische Entladungen treffen. |
| P261 |
Einatmen von Staub vermeiden. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P270 |
Bei Gebrauch nicht essen, trinken oder rauchen. |
| P271 |
Nur im Freien oder in gut belüfteten Räumen verwenden. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
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Arteether Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Arteether reached the market in the Netherlands as a solution in sesame oil,
administered by i.m. injection, for the treatment of severe malaria infections in children and
adolescents. Artheether, a sesquiterpene acetal with an endoperoxide bridge, is an ether
derivative of the naturally occuring compound artemisinin, the active component of
Chinese herbal remedies. As the other structural analogs of artemisinin, such as
artesunate or artemether, it acts rapidly against Plasmodium, the parasite responsible for
the disease, during the early blood stage of its development. It also exhibits a
gametocytocidal activity against Plasmodium falciparum, reducing its potential for
transmission. Because the only controlled clinical studies had been performed in children
and adolescents, this new antimalarial drug was only approved for young patients. Further
studies in adults treated with 150 mg i.m. artemotil, once daily for three consecutive days,
indicated that the drug was efficient, rapidly acting (parasite clearance time meanly 38 h)
and well tolerated. A new promising achievement in the regression of malaria is the
combination of artemisinin derivatives with other long-lived antimalarials as mefloquine or
pyrimethamine/sulfa.
Chemische Eigenschaften
White Crystalline Solid
Verwenden
Derivative of Artemisinin. Antimalarial
Arteether Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
(3R,12aR)-3,6α,9β-Trimethyl-3β,12α-epoxy-3,4,5,5aα,6,7,8,8aα,9,10-decahydro-10α-ethoxypyrano[4,3-j]-1,2-benzodioxepin
Deoxy Arteether
Arteether Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 161)Lieferanten
75887-54-6()Verwandte Suche:
- 10-ethoxy-1,5,9-triMethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.0^{4,13}.0^{8,13}]hexadecane
- NSC 665971
- Arteether
- ARPRINOCID
- SM-227
- dihydroartemisinin ethyl ether
- dihydroqinghaosu ethyl ether
- (3R,12aR)-3,6α,9β-Trimethyl-10β-ethoxy-3β,12α-epoxy-3,4,5,5aα,6,7,8,8aα,9,10-decahydropyrano[4,3-j]-1,2-benzodioxepin
- 3,12-Epoxy-12H-pyrano(4,3-J)-1,2-benzodioxepin, 10-ethoxydecahydro-3,6,9-trimethyl-, (3S-(3alpha,5alpha,6alpha,8aalpha,9beta,10beta,12beta,12aalpha))-
- AlphaBetaArteetherC17H28O5
- Alpha Beta Arteether
- aArteether
- (3R,5aS,6R,8aS,9R,10S,12R,12aR)-10-Ethoxydecahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin
- Artemotil
- SM-22
- 10-Ethoxydecahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin
- 3,12-Epoxy-12H-pyrano(4,3-J)-1,2-benzodioxepin, decahydro-10-ethoxy-3,6,9-trimethyl-, (3R-(3alpha,5abeta,6beta,8abeta,9alpha,10alpha,12beta,12ar*))-
- Areether
- Unii-xgl7gfb9yi
- Arteether 75887-54-6
- B-Arteether (WS)Q: What is
B-Arteether (WS) Q: What is the CAS Number of
B-Arteether (WS) Q: What is the storage condition of
B-Arteether (WS) Q: What are the applications of
B-Arteether (WS)
- Arteethe
- (3R,5aS,6R,8aS,9R,10S,12R,12aR)-10-ethoxy-3,6,9-trimethyldecahydro-3H-3,12-epoxy[1,2]dioxepino[4,3-i]isochromene
- 3,12-Epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin, 10-ethoxydecahydro-3,6,9-trimethyl-, (3R,5aS,6R,8aS,9R,10S,12R,12aR)-
- Beta-Arteether
- 75887-54-6
- C17H28O5
- Chiral Reagents
- Heterocycles
- Antimalarial
- Intermediates & Fine Chemicals
- Pharmaceuticals
