Bromfenac sodium
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- CAS-Nr.
- 91714-93-1
- Englisch Name:
- Bromfenac sodium
- Synonyma:
- Bronuck;AHR 10282R;Ahr 10282b;Bromfenac Sodium b;bromfenacsodiumsal;bromfenac sodium salt;Bromfenac sodium USP/EP/BP;Bromfenac Sodium (AHR 10282R);Bromfenac sodium(Diclofenac Impurity 11);Sodium [2-amino-3-(4-bromobenzoyl)phenyl]acetate
- CBNumber:
- CB1121670
- Summenformel:
- C15H11BrNNaO3
- Molgewicht:
- 356.15
- MOL-Datei:
- 91714-93-1.mol
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Bromfenac sodium Eigenschaften
- Schmelzpunkt:
- 285 ºC
- storage temp.
- 2-8°C
- Löslichkeit
- H2O: ≥5mg/mL
- Aggregatzustand
- powder
- Farbe
- faint yellow to dark yellow
- InChIKey
- HZFGMQJYAFHESD-UHFFFAOYSA-M
- CAS Datenbank
- 91714-93-1
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Kennzeichnung gefährlicher |
N |
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| R-Sätze: |
50 |
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| S-Sätze: |
61 |
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| RIDADR |
UN 3077 9 / PGIII |
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| WGK Germany |
3 |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H400 |
Sehr giftig für Wasserorganismen. |
Kurzfristig (akut) gewässergefährdend |
Kategorie 1 |
Warnung |
![GHS hazard pictograms]() src="/GHS09.jpg" width="20" height="20" /> |
P273, P391, P501 |
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| Sicherheit |
| P273 |
Freisetzung in die Umwelt vermeiden. |
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Bromfenac sodium Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Bromfenac Sodium was launched in the US as a potent, orally-active, long lasting peripheral analgesic with antiinflammatory properties. It is structurally similar to ketoprofen and diclofenac and can be prepared in three steps from 2-amino-4’-bromophenone using Gassman’s oxindole synthesis. Duract’s biological effects are a result of its ability to reduce prostaglandin production through inhibition of cyclooxygenase. As a 4-bromo derivative of Amfenac, this modification increased the duration of analgesic activity and antiinflammatory potency. It was also free of any CNS, cardiovascular or autonomic effects. In comparison, 5 mg of Duract was equipotent to 650 mg of ASA and 25 mg was slightly more potent than 400 mg of Ibuprofen.
Verwenden
Bromfenac sodium has been used:
- to study its ability to bind to melanin
- in the synthesis of bromfenac indolinone standard
- to analyze its permeability in porcine conjunctiva
Definition
ChEBI: The sodium salt of bromfenac. Note that 'bromfenac sodium' commonly refers to the sesquihydrate (120638-55-3); this is the anhydrous form.
Bromfenac sodium Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Bromfenac sodium Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 170)Lieferanten
91714-93-1()Verwandte Suche:
- 2-AMINO-3-(4-BROMOBENZOYL)PHENYLACETIC ACID SODIUM
- 2-Amino-3-(4-bromobenzoyl)phenylacetic acid sodium salt
- Sodium [2-amino-3-(4-bromobenzoyl)phenyl]acetate
- Ahr 10282b
- Benzeneacetic acid, 2-amino-3-(4-bromobenzoyl)-, monosodium salt
- Bronuck
- 2-{2-aMino-3-[(4-broMophenyl)carbonyl]phenyl}acetic acid
- AHR 10282R
- Benzeneacetic acid, 2-amino-3-(4-bromobenzoyl)-, sodium salt (1:1)
- 2-Amino-3-(4-bromobenzoyl)benzeneacetic acid sodium salt
- Bromfenac sodium###7-(4-Bromobenzoyl)-1,3- dihydro-2H-indol-2-one
- bromfenac sodium salt
- sodium 2-(2-amino-3-(4-bromobenzoyl)phenyl)acetate
- Bromfenac Sodium b
- Bromfenac sodium USP/EP/BP
- Bromfenac Sodium (AHR 10282R)
- Bromfenac sodiumQ: What is
Bromfenac sodium Q: What is the CAS Number of
Bromfenac sodium Q: What is the storage condition of
Bromfenac sodium Q: What are the applications of
Bromfenac sodium
- bromfenacsodiumsal
- Bromfenac sodium(Diclofenac Impurity 11)
- 91714-93-1
- C15H11BrNO3Na
- Inhibitors
- Aromatic Phenylacetic Acids and Derivatives
