Ertapenem sodium
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- CAS-Nr.
- 153773-82-1
- Englisch Name:
- Ertapenem sodium
- Synonyma:
- Invanz;ErtapeneM MonosodiuM;3-(((3S;L 749345;EtapeneM;Etapenem sodium;ErtapeneM Crude;Ertapenem Sodium;Ertapenem Impurity 16;TIANFU CHEM---EtapeneM
- CBNumber:
- CB11238838
- Summenformel:
- C22H26N3NaO7S
- Molgewicht:
- 499.51
- MOL-Datei:
- 153773-82-1.mol
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Ertapenem sodium Eigenschaften
- Schmelzpunkt:
- >174oC (dec.)
- storage temp.
- -70°C
- Löslichkeit
- DMSO (Slightly), Methanol (Slightly), Water (Slightly, Sonicated)
- Aggregatzustand
- powder
- Farbe
- white to beige
- Wasserlöslichkeit
- Fully miscible in water. Soluble in DMSO.
- Stabilität:
- Hygroscopic, Temperature Sensitive
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitsschädlich bei Verschlucken. |
Akute Toxizität oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
| H317 |
Kann allergische Hautreaktionen verursachen. |
Sensibilisierung der Haut |
Kategorie 1A |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P261, P272, P280, P302+P352,P333+P313, P321, P363, P501 |
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| Sicherheit |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen. |
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Ertapenem sodium Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Ertapenem sodium has been used as a carbapenem in the NitroSpeed-Carba NP test in minimum inhibitory concentration (MIC) testing for differentiation of carbapenemases in
Enterobacterales and
Pseudomonas aeruginosa. It has also been used as an antibiotic to study its effects on the survival of septic mice.
Definition
ChEBI: The monosodium salt of ertapenem. It is used for the treatment of moderate to severe susceptible infections including intra-abdominal and acute gynaecological infections, pneumonia, and infections of the skin and of the urinary tract. It is more stable to
renal dehydropeptidase I tham imipenem, and so unlike imipenem, its use with cilastatin, which inhibits the enzyme, is not required.
Biochem/physiol Actions
Ertapenem is a broad spectrum carbopenem antibiotic. Ertapenem is active against both gram-positive and gram-negative bacteria. Ertapenem shows an extended duration of action in vivo due to its reversible binding to serum protein.
Ertapenem sodium Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Ertapenem sodium Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 192)Lieferanten
- 1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 3-(((3S,5S)-5-(((3-ca rboxyphenyl)amino)carbonyl)-3-pyrrolidinyl)thio)-6-((1R)-1-hydroxyethy l)-4-methyl-7-oxo-, monosodium salt, (4R,5S,6S)-
- (4R,5S,6S)-3-[[(3S,5S)-5-[[(3-Carboxyphenyl)amino]carbonyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid sodium salt (1:1)
- L 749345
- EtapeneM,Invanz,MK-0826,L-749,345
- EtapeneM
- ErtapeneM Crude
- Etapenem sodium
- Ertapenem sodium, >=97%
- He Seoul sodium imipenem
- Ertapenem Monosodium (90%)
- 3-(((3S
- 5S)-5-(((3-ca rboxyphenyl)amino)carbonyl)-3-pyrrolidinyl)thio)-6-((1R)-1-hydroxyethy l)-4-methyl-7-oxo-
- [4R-[3(3S*,5S*),4α,5β,6β(R*)]]-3-[[-5-[[(3-carboxyphenyl)amino]carbonyl]-3-pyrrolidinyl]thio]-6-(1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid monosodium
- sodium 3-[[[(2S,4S)-4-[[(4R,5S,6S)-2-carboxy-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-en-3-yl]thio]-2-pyrrolidinyl]-oxomethyl]amino]benzoate
- Ertapenem monosodium salt
- Ertapenem Impurity 16
- Ertapenem Sodium USP/EP/BP
- 1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 3-(((3S,5S)-5-(((3-ca rboxyphenyl)amino)carbonyl)-3-pyrrolidinyl)thio)-6-((1R)-1-hydroxyethy l)-4-methyl-7-oxo-, monosodium salt, (4R,5S,6S)- USP/EP/BP
- Sodium (4R,5S,6S)-3-(((3S,5S)-5-((3-carboxyphenyl)carbamoyl)pyrrolidin-3-yl)thio)-6-((R)-1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate
- 1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 3-(((3S,5S)...
- Ertapenem sodiumQ: What is
Ertapenem sodium Q: What is the CAS Number of
Ertapenem sodium Q: What is the storage condition of
Ertapenem sodium Q: What are the applications of
Ertapenem sodium
- TIANFU CHEM---EtapeneM
- ErtapeneM MonosodiuM
- Invanz
- Ertapenem Sodium
- (4R,5S,6S)-3-(((3S,5S)-5-(((3-ca Rboxy-phenyl)amino)carbonyl)-pyrrolidin-3-yl)thio)-6-((1R)-1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo(3.2.0)hept-2-en-2-carboxylic acid monosodium salt
- (4R,5S,6S)-3-(((3S,5S)-5-((3-carboxyphenyl)carbamoyl)pyrrolidin-3-yl)thio)-6-((R)-1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, sodium salt
- 153773-82-1
- C22H24N3NaO7S
- C22H25N3O7SNa
- C22H24N3O7SNa
