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Homatropinhydrobromid Produkt Beschreibung

Homatropine Hydrobromide Struktur
51-56-9
CAS-Nr.
51-56-9
Bezeichnung:
Homatropinhydrobromid
Englisch Name:
Homatropine Hydrobromide
Synonyma:
DL-Hydrobromide;r,hbr,endo-(+-);Homatropine HBr;HoMatropineHBrUSP;Isopto Homatropine;Homatropinhydrobromid;endo-(+/-)-hydrobromid;(+-)-homatropinebromide;HOMATROPINE HYDROBROMIDE;HomatropineHydrobromideGr
CBNumber:
CB1185212
Summenformel:
C16H22BrNO3
Molgewicht:
356.25
MOL-Datei:
51-56-9.mol

Homatropinhydrobromid Eigenschaften

Schmelzpunkt:
214-217 °C
storage temp. 
2-8°C
Löslichkeit
Freely soluble in water, sparingly soluble in alcohol.
Aggregatzustand
neat
Wasserlöslichkeit
soluble
Merck 
14,4730
CAS Datenbank
51-56-9(CAS DataBase Reference)
EPA chemische Informationen
Homatropine hydrobromide (51-56-9)

Sicherheit

Kennzeichnung gefährlicher T
R-Sätze: 23/24/25
S-Sätze: 45-24/25-22
RIDADR  1544
WGK Germany  3
RTECS-Nr. YM5602000
HazardClass  6.1
PackingGroup  III
HS Code  29399900

Homatropinhydrobromid Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:

R23/24/25:Giftig beim Einatmen, Verschlucken und Berührung mit der Haut.

S-Sätze Betriebsanweisung:

S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
S24/25:Berührung mit den Augen und der Haut vermeiden.
S22:Staub nicht einatmen.

Beschreibung

Homatropine is an anticholinergic agent. It reduces acetylcholine-induced contractions of isolated goat detrusor muscle strips when used at a concentration of 5 μM. Homatropine (1 μM) inhibits acetylcholine- or methacholine-induced contraction of isolated rat anococcygeus muscle. It inhibits serotonin- or thrombin-induced platelet aggregation in isolated sheep platelet-rich plasma (IC50s = 4.3 and 100 μM, respectively). Topical ophthalmic administration of homatropine induces partial mydriasis in Angora goats.

Chemische Eigenschaften

white crystals or crystalline powder

Verwenden

Homatropine is an anticholinergic agent. Homatropine acts as an inhibitor of the muscarinic acetylcholine receptors. Homatropine is used in eye drops as a cycloplegic and as a mydriatic, to dilate the pupil.

Verwenden

anticholinergic (opthalmic)

Trademarks

Isopto Homatropine (Alcon) .

Allgemeine Beschreibung

Homatropine hydrobromide,1 H,5 H-tropan-3 -ol mandelate (ester) hydrobromide(Homatrocel), occurs as white crystals or as awhite, crystalline powder that is affected by light. It is solublein water (1:6) and alcohol (1:40), less soluble in chloroform(1:420), and insoluble in ether.
Solutions are incompatible with alkaline substances,which precipitate the free base, and with the commonreagents that precipitate alkaloids. As with atropine, solutionsare sterilized best by filtration through a bacteriologicalfilter.

Clinical Use

Homatropine hydrobromide is used topically to paralyzethe ciliary structure of the eye (cycloplegia) and to effectmydriasis. It behaves very much like atropine but is weakerand less toxic. In the eye, it acts more rapidly but less persistentlythan atropine. Dilation of the pupil takes place inabout 15 to 20 minutes, and the action subsides in about24 hours. By using a miotic, such as physostigmine, it ispossible to restore the pupil to normality in a few hours.

Homatropinhydrobromid Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Homatropinhydrobromid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 146)Lieferanten
Firmenname Telefon Fax E-Mail Land Produktkatalog Edge Rate
Henan DaKen Chemical CO.,LTD.
+86-371-66670886
info@dakenchem.com China 15427 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com China 22607 55
career henan chemical co
+86-0371-55982848
sales@coreychem.com China 29954 58
Hubei Jusheng Technology Co.,Ltd.
86-18871470254
027-59599243 linda@hubeijusheng.com CHINA 28229 58
Chongqing Chemdad Co., Ltd
+86-13650506873
sales@chemdad.com CHINA 37282 58
Alchem Pharmtech,Inc.
8485655694
sales@alchempharmtech.com United States 63726 58
CONIER CHEM AND PHARMA LIMITED
86-18523575427
sales@conier.com China 47498 58
SIMAGCHEM CORP
13806087780 +86 13806087780
shaobowang@simagchem.com CHINA 17384 58
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418671
0551-65418697 sales@tnjchem.com CHINA 37441 58
Dideu Industries Group Limited
029-88380327
Service@dideu.com CHINA 30014 58

51-56-9(Homatropinhydrobromid)Verwandte Suche:


  • alpha-hydroxybenzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester hydrobromide
  • MANDELYTROPINE HYDROBROMIDE
  • (+/-)-HOMATROPINE HYDROBROMIDE
  • HOMATROPINE HYDROBROMIDE
  • DL-HOMATROPINE HYDROBROMIDE
  • (+-)-homatropinebromide
  • 1-alpha-h,5-alpha-h-tropan-3-alpha-ol,mandelate(ester),hydrobromide
  • Tropine mandelate hydrobromide, DL-endo-α-Hydroxybenzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester hydrobromide
  • 1aH,5aH-Tropan-3a-ol, mandelate (ester), hydrobromide
  • Benzeneacetic acid, a-hydroxy-, (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, hydrobromide
  • (RS)-3alpha(1alphaH,5alphaH)-Tropanylmandelat hydrobromide
  • HOMATROPINE HYDROBROMIDE(RG)
  • HoMatropineHBrUSP
  • endo-8-Methyl-8-azabicyclo[3.2.1]octan-3-yl 2-hydroxy-2-phenylacetate hydrobroMide
  • 1αH,5αH-Tropan-3α-ol Mandelate (Ester) HydrobroMide
  • rac HoMatropine HydrobroMide
  • α-Hydroxybenzeneacetic Acid (3-Endo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl Ester, HydrobroMide
  • DL-endo-α-Hydroxybenzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester hydrobromide
  • Tropine mandelate hydrobromide
  • (1R,3r,5S)-8-Methyl-8-azabicyclo[3.2.1]octan-3-yl 2-hydroxy-2-phenylacetate hydrobroMide
  • Benzeneacetic acid, α-hydroxy-, (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, hydrobromide (1:1)
  • DL-Hydrobromide
  • 8-methyl-8-azabicyclo[3.2.1]oct-3-yl hydroxy(phenyl)acetate hydrobromide
  • alpha-hydroxy-benzeneaceticaci8-methyl-8-azabicyclo(3.2.1)oct-3-yleste
  • benzeneaceticacid,alpha-hydroxy-,8-methyl-8-azabicyclo[3.2.1]oct-3-ylester,
  • endo-(+/-)-hydrobromid
  • r,hbr,endo-(+-)
  • HOMATROPINEHYDROBROMIDE,CRYSTAL,USP
  • 1αH,5αH-Tropan-3α-ol, mandelate (ester), hydrobromide (8CI)
  • Benzeneacetic acid, α-hydroxy-, (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, hydrobromide
  • Benzeneacetic acid, α-hydroxy-, 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, hydrobromide, endo-
  • Isopto Homatropine
  • Mandelic acid tropine ester hydrobromide
  • Homatropinhydrobromid
  • Homatropine HBr
  • HomatropineHydrobromideGr
  • DL-Homatropine hydrobromide, 98.5-100.5%
  • Homatropine hydrobromide CRS
  • Hyoscine hydrobromide CRS
  • Homatropine Methylbromide EP Impurity B
  • Homatropine Hydrobromide USP/EP/BP
  • dextro,laevo-homatropine hydrobromide
  • Homatropine Bromide (Homatropine hydrobromide)
  • 51-56-9
  • C16H21NO3HBr
  • C16H20NO3
  • C16H22NO3Br
  • Alkaloids
  • Tropane Alkaloids
  • Aromatics
  • Heterocycles
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Acetylcholine receptor
  • ISOPTO
  • Miscellaneous Natural Products
  • Alkaloids
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