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2,4-DIHYDROXY-6-METHYLBENZOIC ACID

2,4-DIHYDROXY-6-METHYLBENZOIC ACID Struktur
480-64-8
CAS-Nr.
480-64-8
Englisch Name:
2,4-DIHYDROXY-6-METHYLBENZOIC ACID
Synonyma:
133346;Orsellic acid;o-orsellinicaci;ORSELLINIC ACID;o-orsellinic acid;ORSELLINIC ACID MONOHYDRATE;2,4-DIHYDROXY-6-METHYLBENZOIC ACID;6-Methyl-2,4-dihydroxybenzoic acid;2-Methyl-4,6-dihydroxybenzoic acid;Benzoic acid, 2,4-dihydroxy-6-Methyl-
CBNumber:
CB1185500
Summenformel:
C8H8O4
Molgewicht:
168.15
MOL-Datei:
480-64-8.mol
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2,4-DIHYDROXY-6-METHYLBENZOIC ACID Eigenschaften

Schmelzpunkt:
173-174°C
Siedepunkt:
257.07°C (rough estimate)
Dichte
1.3037 (rough estimate)
Brechungsindex
1.5090 (estimate)
storage temp. 
Sealed in dry,Room Temperature
Löslichkeit
Ethyl Acetate (Slightly), Methanol (Slightly)
Aggregatzustand
Solid
pka
pK (25°) 3.90
Farbe
White to Pale Gray
Wasserlöslichkeit
Soluble in water, dimethyl sulfoxide or 100% ethanol.
Stabilität:
Hygroscopic
CAS Datenbank
480-64-8
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizität (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P261 Einatmen von Staub vermeiden.
P304+P340 BEI EINATMEN: Die Person an die frische Luft bringen und für ungehinderte Atmung sorgen.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.
P405 Unter Verschluss aufbewahren.

2,4-DIHYDROXY-6-METHYLBENZOIC ACID Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Orsellinic acid is a fungal metabolite and benzoic acid derivative with antioxidant and neuroprotective activities. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) radicals with an IC50 value of 5 mM. Orsellinic acid (1 μg/ml) prevents PARP cleavage induced by platelet-activating factor (PAF) in PC12-AC cells and PAF-induced cytotoxicity in PAF receptor null (Pafr-/-) mouse cerebellar granule cells.

Verwenden

Orsellinic acid is a benzoic acid compound shown to block PAF-mediated neuronal apoptosis.

Definition

ChEBI: A dihydroxybenzoic acid that is 2,4-dihydroxybenzoic acid in which the hydrogen at position 6 is replaced by a methyl group.

Biosynthese

One of the simplest polyketide derivatives, orsellinic acid is widely distributed in fungi. It is biosynthesised from an acetate starter unit and three malonyl units, as shown in Figure. Intramolecular condensation of the polyketide chain gives orsellinic acid without further modification.
The biosynthesis of orsellinic acid
The biosynthesis of orsellinic acid.

2,4-DIHYDROXY-6-METHYLBENZOIC ACID Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Tetraacetic acid EVERNIC ACID GYROPHORIC ACID 2 4-DIHYDROXY-6-METHYLBENZALDEHYDE 4-[(4-Methoxy-6-methylsalicyloyl)oxy]-6-methylsalicylsure LECANORIC ACID S-(Hydrogenmalonyl)coenzym A 2,4-DIMETHOXY-6-METHYLBENZOIC ACID 5-Methylresorcin S-Acetylcoenzym A Kohlenstoffdioxid

Downstream Produkte

Ethyl 2,4-dihydroxy-6-methylbenzoate

2,4-DIHYDROXY-6-METHYLBENZOIC ACID Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 116)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Henan Fengda Chemical Co., Ltd 		+86-371-86557731 +86-13613820652
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Hubei xin bonus chemical co. LTD 		86-13657291602
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Alchem Pharmtech,Inc. 		8485655694
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 factory@coreychem.com China 29826 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
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Henan Alfa Chemical Co., Ltd 		+8618339805032
 alfa4@alfachem.cn China 12755 58
LEAP CHEM CO., LTD. 		+86-852-30606658
market18@leapchem.com China 24738 58
Taizhou Blazer Biomedical Technology Co., Ltd. 		0523-86112008 13915404123
 sales@blazerbio.com China 88 58

480-64-8()Verwandte Suche:

Methyl-2,4-dihydroxy-m-toluat 4-[(4-Methoxy-6-methylsalicyloyl)oxy]-6-methylsalicylsure [(7-Carboxy-4-formyl-3,8-dihydroxy-1,6-dimethyl-11-oxo-11H-dibenzo[b,e][1,4]dioxepin-9-yl)methyl]hydrogenfumarat Mycophenolinsäure 3,4,5,6,9,10-Hexahydro-14,16-dihydroxy-3-methyl-1H-2-benzoxacy-clotetradecin-1,7(8H)-dion,(S-(E))- 3-Hydroxy-4-(methoxycarbonyl)-2,5-dimethylphenyl-3-formyl-2,4-dihydroxy-6-methylbenzoat Methyl-3-chlor-4-hydroxy-6-methylsalicylat
  • 2,4-DIHYDROXY-6-METHYLBENZOIC ACID
  • ORSELLINIC ACID
  • ORSELLINIC ACID MONOHYDRATE
  • 2,4-Dihydroxy-6-methylbenzoic acid hydrate, 97%
  • 2-Methyl-4,6-dihydroxybenzoic acid
  • 6-Methyl-2,4-dihydroxybenzoic acid
  • Orsellic acid
  • o-orsellinic acid
  • Benzoic acid, 2,4-dihydroxy-6-Methyl-
  • 133346
  • o-orsellinicaci
  • 480-64-8
  • Inhibitors
  • Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
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