4-Thia-1-azabicyclo[3.2.0]heptan-2-carbonsure, 6-[[[[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-, Mononatriumsalz, [2S-[2α,5α,6β,(S*)]]-
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- CAS-Nr.
- 59703-84-3
- Bezeichnung:
- 4-Thia-1-azabicyclo[3.2.0]heptan-2-carbonsure, 6-[[[[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-, Mononatriumsalz, [2S-[2α,5α,6β,(S*)]]-
- Englisch Name:
- Piperacillin sodium salt
- Synonyma:
- PIPERACILLIN SODIUM;t1220;pipril;C07361;cl227193;pentcillin;PIPERACILLIN NA;DBL Piperacillin;sodiumpiperacillin;PEPERACILLIN SODIUM
- CBNumber:
- CB1237614
- Summenformel:
- C23H26N5NaO7S
- Molgewicht:
- 539.54
- MOL-Datei:
- 59703-84-3.mol
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4-Thia-1-azabicyclo[3.2.0]heptan-2-carbonsure, 6-[[[[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-, Mononatriumsalz, [2S-[2α,5α,6β,(S*)]]- Eigenschaften
- Schmelzpunkt:
- 183-185 C (dec.)
- Siedepunkt:
- 793℃
- Brechungsindex
- 180 ° (C=0.8, H2O)
- storage temp.
- Inert atmosphere,2-8°C
- Löslichkeit
- H2O: 50 mg/mL, clear, colorless to faintly yellow
- Farbe
- White to Almost white
- Wasserlöslichkeit
- Soluble in ethanol, water and methanol.
- Merck
- 14,7463
- BRN
- 5373920
- Stabilität:
- Hygroscopic
- InChIKey
- WCMIIGXFCMNQDS-IDYPWDAWSA-M
- CAS Datenbank
- 59703-84-3(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Kennzeichnung gefährlicher |
Xn |
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| R-Sätze: |
42/43 |
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| S-Sätze: |
22-36/37-45 |
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| WGK Germany |
2 |
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| RTECS-Nr. |
XI0180000 |
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| HS Code |
29411099 |
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| Toxizität |
LD50 in mice, rats, dogs, monkeys (g/kg): 5, 2.7, >6, >4 i.v. (Takai) |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H317 |
Kann allergische Hautreaktionen verursachen. |
Sensibilisierung der Haut |
Kategorie 1A |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P261, P272, P280, P302+P352,P333+P313, P321, P363, P501 |
| H334 |
Kann bei Einatmen Allergie, asthmaartige Symptome oder Atembeschwerden verursachen. |
Sensibilisierung der Atemwege |
Kategorie 1 |
Achtung |
![GHS hazard pictograms]() src="/GHS08.jpg" width="20" height="20" /> |
P261, P285, P304+P341, P342+P311,P501 |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P284 |
Atemschutz tragen. |
| P304+P340 |
BEI EINATMEN: Die Person an die frische Luft bringen und für ungehinderte Atmung sorgen. |
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4-Thia-1-azabicyclo[3.2.0]heptan-2-carbonsure, 6-[[[[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-, Mononatriumsalz, [2S-[2α,5α,6β,(S*)]]- Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R42/43:Sensibilisierung durch Einatmen und Hautkontakt möglich.
S-Sätze Betriebsanweisung:
S22:Staub nicht einatmen.
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
Beschreibung
Piperacillin was synthesized by Toyama Chemicals Company in 1976by acylation of the amino residue of ampicillin. It shows excellent activity against a wide range of grampositive and gram-negative bacteria and has been used as the most potent semisynthetic penicillin. Piperacillin is administered intravenously or intramuscularly for therapy of sepsis, meningitis, respiratory and urinary tract infections, and for abdominal infections caused by Staphylococcus, Streptococcus, Escherichia coli, Klebsiella, Haemophilus influenzae, Serratia marcescens, Pseudomonas aeruginosa, Proteus, Enterobacter, Citrobacter, and Bacteroides.
Chemische Eigenschaften
White to off-white crystalline powder
Verwenden
A broad spectrum antibiotic targeting a wide range of susceptible gram positive and gram negative bacteria. Piperacillin sodium salt is an antibiotic. It is used in pharmacokinetic studies to optimize antimicrobial therapy and in hypersensitivity reactions. It is involved in the study of multidrug-resistant organisms. It acts as an antibiotic related to penicillin.
Trademarks
Pipracil (Wyeth).
4-Thia-1-azabicyclo[3.2.0]heptan-2-carbonsure, 6-[[[[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-, Mononatriumsalz, [2S-[2α,5α,6β,(S*)]]- Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
4-Thia-1-azabicyclo[3.2.0]heptan-2-carbonsure, 6-[[[[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-, Mononatriumsalz, [2S-[2α,5α,6β,(S*)]]- Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 311)Lieferanten
59703-84-3(4-Thia-1-azabicyclo[3.2.0]heptan-2-carbonsure, 6-[[[[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-, Mononatriumsalz, [2S-[2α,5α,6β,(S*)]]-)Verwandte Suche:
- PIPERACILLIN NA
- [2s-[2alpha,5alpha,6beta(s*)]]-6-[[[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid monosodium salt
- (2s-(2-alpha,5-alpha,6-beta(s*)))-msal
- 3-dimethyl-7-oxo--piperazinyl)carbonyl)amino)phenylacetyl)amino)-monosodiu
- 4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylicacid,6-(((((4-ethyl-2,3-dioxo-1
- cl227193
- pentcillin
- pipril
- sodiumpiperacillin
- t1220
- 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-, monosodium salt, [2S-[2alpha,5alpha,6beta(S*)]]-
- Piperacillin sodium sterile
- PIPERACILLIN SODIUM IMP. E (EP): 1-ETHYLPIPERAZINE-2,3-DIONE MM(CRM STANDARD)
- PIPERACILLIN SODIUM IMP. H (EP): 6-AMINOPENICILLANIC ACID MM(CRM STANDARD)
- PIPERACILLIN SODIUM MM(CRM STANDARD)
- PEPERACILLIN SODIUM
- 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2R)-[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-, monosodium salt, (2S,5R,6R)- (9CI)
- 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-, monosodium salt, [2S-[2a,5a,6b(S*)]]-
- Piperacillin sodium salt
- DBL Piperacillin
- 6α-[(R)-Phenyl[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonylamino]acetylamino]penicillanic acid sodium salt
- 6α-[[(R)-(4-Ethyl-2,3-dioxo-1-piperazinylcarbonylamino)phenylacetyl]amino]penicillanic acid sodium salt
- C07361
- TazobactaM SodiuM (sterile one)
- 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2R)-2-[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-, sodium salt (1:1), (2S,5R,6R)-
- (2s-(2alpha,5alpha,6beta(s*)))-6-(((((4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl)amino)phenylacetyl)amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid mono
- TazobactaM SodiuM / Piperacillin SodiuM
- (2S,5R,6R)-6-[(R)-2-(4-Ethyl-2,3-dioxo-1-piperazinecarboxamido)-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid sodium salt
- Piperacilin Sodium + Tazobactam Sodium(8：1)
- sodium (2R,5S,6S)-6-[[(2R)-2-[[(4-ethyl-2,3-dioxo-1-piperazinyl)-oxomethyl]amino]-1-oxo-2-phenylethyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
- Piperacillin sodium salt, 98%,HPLC
- Piperacilin Sodium Salt
- PiperacillinSodiumSalt>
- Piperacillin Sodium/Tazobactam Sodium(8:1)
- Sodium (2S,5R,6R)-6-((R)-2-(4-ethyl-2,3-dioxopiperazine-1-carboxamido)-2-phenylacetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
- Piperacillin sodium salt USP/EP/BP
- Piperacillin sodiumQ: What is
Piperacillin sodium Q: What is the CAS Number of
Piperacillin sodium Q: What is the storage condition of
Piperacillin sodium Q: What are the applications of
Piperacillin sodium
- PIPERACILLIN SODIUM
- Pipracillin sodium salt
- Glecaprevir Impurity 4
- 59703-84-3
- C23H26N5NaO7S
- C23H27N5O7SNa
- C6H10O4C4H10N2
- C23H28N5O7SNa
- C23H26N5O7SNa
- BioChemical
- Antibiotics
- Antibiotics N-S
- Antibiotics A to Z
- Interferes with Cell Wall SynthesisSpectrum of Activity
- Antibacterial
- Antibiotics
- Antibiotics A to
- Antibiotics N-SAntibiotics
- Chemical Structure Class
- L - ZAntibiotics
- Mechanism of Action
