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Lecithine Produkt Beschreibung

Lecithin Struktur
8002-43-5
CAS-Nr.
8002-43-5
Bezeichnung:
Lecithine
Englisch Name:
Lecithin
Synonyma:
PC;kelecin;LECITHIN;froM Egg;Alcolec-S;granulestin;L-α-Lecithin;Lecithin, NF;LIPOID(R)E80;Lecithin 
CBNumber:
CB1242041
Summenformel:
C42H80NO8P
Molgewicht:
758.06
MOL-Datei:
8002-43-5.mol

Lecithine Eigenschaften

Dichte
d424 1.0305
Flammpunkt:
57 °C
storage temp. 
2-8°C
Löslichkeit
chloroform: 0.1 g/mL, slightly hazy, slightly yellow to deep orange
Aggregatzustand
solution
Farbe
Pale Brown to Yellow
Wasserlöslichkeit
NEGLIGIBLE
Merck 
14,5429
BRN 
5209585
Stabilität:
Stable, but light, heat, moisture and air-sensitive. Incompatible with strong oxidizing agents.
InChIKey
FWMYJLDHIVCJCT-VSZGHEPYSA-N
CAS Datenbank
8002-43-5
EPA chemische Informationen
Lecithins(8002-43-5)
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
Kennzeichnung gefährlicher T,Xn,F,N
R-Sätze: 11-48/20/22-40-38-22-36/37/38-46-45-48/20/21/22-36/38-20/22-63-67-65-62-51/53-48/20
S-Sätze: 7-16-24/25-36/37-45-36/37/39-26-53-62-61-22
RIDADR  UN 2810 6.1/PG 2
WGK Germany  3
RTECS-Nr. OG7565000
1-8-10
TSCA  Yes
HS Code  29239000
Giftige Stoffe Daten 8002-43-5(Hazardous Substances Data)
Bildanzeige (GHS)
Alarmwort Achtung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H225 Flüssigkeit und Dampf leicht entzündbar. Entzündbare Flüssigkeiten Kategorie 2 Achtung P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H302 Gesundheitsschädlich bei Verschlucken. Akute Toxizität oral Kategorie 4 Warnung P264, P270, P301+P312, P330, P501
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung P264, P280, P305+P351+P338,P337+P313P
H331 Giftig bei Einatmen. Akute Toxizität inhalativ Kategorie 3 Achtung P261, P271, P304+P340, P311, P321,P403+P233, P405, P501
H336 Kann Schläfrigkeit und Benommenheit verursachen. Spezifische Zielorgan-Toxizität (einmalige Exposition) Kategorie 3 (Schläfrigkeit und Benommenheit) Warnung P261, P271, P304+P340, P312,P403+P233, P405, P501
H351 Kann vermutlich Krebs verursachen. Karzinogenität Kategorie 2 Warnung P201, P202, P281, P308+P313, P405,P501
H372 Schädigt bei Hautkontakt und Verschlucken die Organe bei längerer oder wiederholter Exposition. Spezifische Zielorgan-Toxizität (wiederholte Exposition) Kategorie 1 Achtung P260, P264, P270, P314, P501
Sicherheit
P201 Vor Gebrauch besondere Anweisungen einholen.
P210 Von Hitze, heißen Oberflächen, Funken, offenen Flammen und anderen Zündquellenarten fernhalten. Nicht rauchen.
P261 Einatmen von Staub vermeiden.
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.
P308+P313 BEI Exposition oder falls betroffen: Ärztlichen Rat einholen/ärztliche Hilfe hinzuziehen.
P337+P313 Bei anhaltender Augenreizung: Ärztlichen Rat einholen/ärztliche Hilfe hinzuziehen.
P403+P233 An einem gut belüfteten Ort aufbewahren. Behälter dicht verschlossen halten.
P403+P235 An einem gut belüfteten Ort aufbewahren. Kühl halten.

Lecithine Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:

R11:Leichtentzündlich.
R48/20/22:Gesundheitsschädlich: Gefahr ernster Gesundheitsschäden bei längerer Exposition durch Einatmen und durch Verschlucken.
R40:Verdacht auf krebserzeugende Wirkung.
R38:Reizt die Haut.
R22:Gesundheitsschädlich beim Verschlucken.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
R46:Kann vererbbare Schäden verursachen.
R45:Kann Krebs erzeugen.
R48/20/21/22:Gesundheitsschädlich: Gefahr ernster Gesundheitsschäden bei längerer Exposition durch Einatmen, Berührung mit der Haut und durch Verschlucken.

S-Sätze Betriebsanweisung:

S7:Behälter dicht geschlossen halten.
S16:Von Zündquellen fernhalten - Nicht rauchen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S53:Exposition vermeiden - vor Gebrauch besondere Anweisungen einholen.

Beschreibung

Food-grade lecithin is obtained from soybeans and other plant sources. It is a complex mixture of acetone-insoluble phosphatides that consists chiefly of phosphatidyl choline, phosphatidyl etha nolamine, and phosphatidyl inositol, combined with various amounts of other substances such as triglycerides, fatty acids, and carbohydrates. Refined grades of lecithin may contain any of these components in varying proportions and combinations depending on the type of fractionation used. In its oil-free form, the prepon-derance of triglycerides and fatty acids is removed and the product contains 90% or more of phosphatides representing all or certain fractions of the total phosphatide complex. The consistency of both natural grades and refined grades of lecithin may vary from plastic to fluid, depending upon free fatty acid and oil content, and upon the presence or absence of other diluents. Its color varies from light yellow to brown, depending on the source, on crop variations, and on whether it is bleached or unbleached. It is odorless or has a characteristic, slight nutlike odor and a bland taste. Edible diluents, such as cocoa butter and vegetable oils, often replace soybean oil to improve functional and flavor characteris tics. Lecithin is only partially soluble in water, but it readily hydrates to form emulsions. The oil-free phosphatides are soluble in fatty acids, but are practically insoluble in fixed oils. When all phosphatide fractions are present, lecithin is partially soluble in alcohol and practically insoluble in acetone.

Chemische Eigenschaften

Lecithins vary greatly in their physical form, from viscous semiliquids to powders, depending upon the free fatty acid content. They may also vary in color from brown to light yellow, depending upon whether they are bleached or unbleached or on the degree of purity. When they are exposed to air, rapid oxidation occurs, also resulting in a dark yellow or brown color.
Lecithins have practically no odor. Those derived from vegetable sources have a bland or nutlike taste, similar to that of soybean oil.

Chemische Eigenschaften

solid

Verwenden

Edible and digestible surfactant and emulsifier of natural origin. Used in margarine, chocolate and in the food industry in general. In pharmaceuticals and cosmetics. Many other industrial uses, e.g. treating leather and textiles.

Verwenden

lecithin (hydrogenated) is an emulsifier.

Verwenden

lecithin is a natural emollient, emulsifier, anti-oxidant, and spreading agent, lecithin is a hydrophilic ingredient that attracts water and acts as a moisturizer. generally obtained for cosmetic products from eggs and soybeans, it is found in all living organisms.

Verwenden

egg lecithin is emollient and particularly recommended for sensitive skin.

Verwenden

Lecithin is an emulsifier that is a mixture of phosphatides which are typically surface-active. it is now commercially obtained from soy- beans; previously it was obtained from egg yolk. it is used in marga- rine as an emulsifier and antispatter agent; in chocolate manufacture it controls flow properties by reducing viscosity and reducing the cocoa butter content from 3 to 5%; it is used as a wetting agent in cocoa powder, fillings, and beverage powders; an antisticking agent in griddling fat; and in baked goods to assist the shortening mix with other dough ingredients and to stabilize air cells. typical usage levels range from 0.1 to 1.0%.

Definition

ChEBI: A glycerophosphocholine compound having O-acyl substituents at both the 1- and 2-positions of the glycerol. It is a major constituent of cell membranes.

Vorbereitung Methode

Lecithins are essential components of cell membranes and, in principle, may be obtained from a wide variety of living matter. In practice, however, lecithins are usually obtained from vegetable products such as soybean, peanut, cottonseed, sunflower, rapeseed, corn, or groundnut oils. Soybean lecithin is the most commercially important vegetable lecithin. Lecithin obtained from eggs is also commercially important and was the first lecithin to be discovered.
Vegetable lecithins are obtained as a by-product in the vegetable oil refining process. Polar lipids are extracted with hexane and, after removal of the solvent, a crude vegetable oil is obtained. Lecithin is then removed from the crude oil by water extraction. Following drying, the lecithin may be further purified.
With egg lecithin, a different manufacturing process must be used since the lecithin in egg yolks is more tightly bound to proteins than in vegetable sources. Egg lecithin is thus obtained by solvent extraction from liquid egg yolks using acetone or from freeze-dried egg yolks using ethanol (95%).
Synthetic lecithins may also be produced.

Pharmazeutische Anwendungen

Lecithins are used in a wide variety of pharmaceutical applications. They are also used in cosmetics and food products.
Lecithins are mainly used in pharmaceutical products as dispersing, emulsifying, and stabilizing agents, and are included in intramuscular and intravenous injections, parenteral nutrition formulations, and topical products such as creams and ointments.
Lecithins are also used in suppository bases, to reduce the brittleness of suppositories, and have been investigated for their absorption-enhancing properties in an intranasal insulin formulation. Lecithins are also commonly used as a component of enteral and parenteral nutrition formulations.
There is evidence that phosphatidylcholine (a major component of lecithin) is important as a nutritional supplement to fetal and infant development. Furthermore, choline is a required component of FDA-approved infant formulas. Other studies have indicated that lecithin can protect against alcohol cirrhosis of the liver, lower serum cholesterol levels, and improve mental and physical performance.
Liposomes in which lecithin is included as a component of the bilayer have been used to encapsulate drug substances; their potential as novel delivery systems has been investigated. This application generally requires purified lecithins combined in specific proportions.
Therapeutically, lecithin and derivatives have been used as a pulmonary surfactant in the treatment of neonatal respiratory distress syndrome.

Sicherheit(Safety)

Lecithin is a component of cell membranes and is therefore consumed as a normal part of the diet. Although excessive consumption may be harmful, it is highly biocompatible and oral doses of up to 80 g daily have been used therapeutically in the treatment of tardive dyskinesia. When used in topical formulations, lecithin is generally regarded as a nonirritant and nonsensitizing material. The Cosmetic Ingredients Review Expert Panel (CIR) has reviewed lecithin and issued a tentative report revising the safe concentration of the material from 1.95% to 15.0% in rinse-off and leave-in products. They note, however, that there are insufficient data to rule on products that are likely to be inhaled.

Lager

Lecithins decompose at extreme pH. They are also hygroscopic and subject to microbial degradation. When heated, lecithins oxidize, darken, and decompose. Temperatures of 160–180°C will cause degradation within 24 hours.
Fluid or waxy lecithin grades should be stored at room temperature or above; temperatures below 10°C may cause separation.
All lecithin grades should be stored in well-closed containers protected from light and oxidation. Purified solid lecithins should be stored in tightly closed containers at subfreezing temperatures.

läuterung methode

Lecithin from hen egg white is purified by solvent extraction and chromatography on alumina. It is suspended in H2O and kept frozen until required [Lee & Hunt J Am Chem Soc 106 7411 1984, Singleton et al. J Am Oil Chem Soc 42 53 1965]. For purification of commercial egg lecithin, see Pangborn [J Biol Chem 188 471 1951].

Inkompatibilitäten

Incompatible with esterases owing to hydrolysis.

Regulatory Status

GRAS listed. Accepted for use as a food additive in Europe. Included in the FDA Inactive Ingredients Database (inhalations; IM and IV injections; otic preparations; oral capsules, suspensions and tablets; rectal, topical, and vaginal preparations). Included in nonparenteral and parenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.

Lecithine Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Lecithine Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 317)Lieferanten
Firmenname Telefon Fax E-Mail Land Produktkatalog Edge Rate
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418684 18949823763
86-0551-65418684 info@tnjchem.com China 1861 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3623 58
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 Abel@chembj.com CHINA 3194 55
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20672 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32447 55
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070;product@chemlin.com.cn
product@chemlin.com.cn CHINA 3015 60
Hebei Chisure Biotechnology Co., Ltd.
+8613292890173
0311 66567340 luna@speedgainpharma.com CHINA 1017 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 30002 58
Hebei Huanhao Biotechnology Co., Ltd.
86-0311-83975816 whatsapp +8618034554576
86-0311-83975816 grace@hbhuanhao.com CHINA 700 58
Chengdu GLP Biotech Co., Ltd
13350802083
scglp@glp-china.com CHINA 1007 58

8002-43-5(Lecithine)Verwandte Suche:


  • Soybean phospholipids
  • LECITHIN SOYBEAN
  • LECITHIN (EX SOYBEANS)
  • LECITHIN SOYA BEAN
  • LECITHIN
  • LECITHIN, FROM SOYBEAN
  • SOYBEAN LECITHIN
  • PHOSPHATIDYLCHOLINE
  • PC
  • VEGETABLE LECITHIN
  • L-α-Lecithin
  • L-α-Phosphatidylcholine
  • Lecithin, granular
  • PHOSPHATIDYLSERINE 20%
  • L-A-PHOSPHATIDYLCHOLINE TYPE X-E FROM*DR IED EGG YOL
  • L-A-PHOSPHATIDYLCHOLINE TYPE II-S*FROM S OYBEAN
  • L-A-PHOSPHATIDYL-CHOLINE TYPE III-S*FROM SOYBEAN
  • 3-SN-PHOSPHATIDYLCHOLINE SOLUTION FROM S OYBEAN
  • 3-SN-PHOSPHATIDYLCHOLINE SOLUTION FROM FROZEN EGG YOLK*
  • L-A-PHOSPHATIDYLCHOLINE TYPE I-EH*HYDROG ENATED
  • L-A-PHOSPHATIDYLCHOLINE TYPE XII-E*FROM FRESH TURKEY
  • L-A-PHOSPHATIDYLCHOLINE TYPE III-B*FROM BOVINE BRAI
  • L-A-PHOSPHATIDYLCHOLINE TYPE XVI-E FROM FRESH EGG Y
  • L-A-PHOSPHATIDYLCHOLINE TYPE IV-S*FROM S OYBEAN
  • 3-SN-PHOSPHATIDYLCHOLINE SOLUTION FROM F RESH EGG YOLK
  • L-A-PHOSPHATIDYLCHOLINE TYPE XI-E*FROM F RESH EGG YO
  • L-A-PHOSPHATIDYLCHOLINE, LYOPHILIZED
  • L-A-PHOSPHATIDYLCHOLINE FROM SOYBEAN*LYO PHILIZED PO
  • 3-SN-PHOSPHATIDYLCHOLINE SOLUTION FROM BOVINE BRAIN*
  • L-A-PHOSPHATIDYLCHOLINE TYPE XIII-E
  • 3-SN-PHOSPHATIDYLCHOLINE SOLUTION FROM BOVINE LIVER*
  • L-A-PHOSPHATIDYLCHOLINE TYPE VI-E*FROM F ROZEN EGG Y
  • L-A-PHOSPHATIDYLCHOLINE TYPE III-H*FROM BOVINE HEAR
  • SoyaLecithin,Liquid,Powder
  • Lecithin from eggs
  • LecithineallerArt
  • Lecithin,Refined
  • LECITHIN FORM SOYBEAN
  • Phosphatidylserine/L--Phosphatidyl-L-serine
  • Lecithin (L-alpha-Phosphatidyl choline: Soybean lecithin)
  • l-a-phosphatidylcholine type XVI-E
  • Lecithin (L-alpha-Phosphatidyl choline
  • L-α-Phosphatidylcholine solution,1,2-Diacyl-sn-glycero-3-phosphocholine, 3-sn-Phosphatidylcholine, L-α-Lecithin
  • L-α-Phosphatidylcholine,1,2-Diacyl-sn-glycero-3-phosphocholine, 3-sn-Phosphatidylcholine, L-α-Lecithin, Azolectin
  • L-α-Phosphatidylcholine, hydrogenated,1,2-Diacyl-sn-glycero-3-phosphocholine, L-α-Lecithin
  • L-alpha-Lecithin, granular
  • Lecithin, NF
  • Phosphatidylcholine (350 mg) (INTERNATIONAL COLD CHAIN SHIPMENT REQUIRED)
  • (SPC,EPC) Lecithin froM egg Lecithin froM soyabean
  • froM Egg
  • Lecithin 
  • L-alpha-Lecithin, granular 1KG
  • L-alpha-Lecithin, granular 250GR
  • Lecithin, 90%, soybean
  • Lecithins(Phosphatides)
  • Lecithin NF GRANULES.
  • L-α-Lecithin, Egg Yolk, Highly Purified - CAS 8002-43-5 - Calbiochem
  • L-α-Lecithin, Soybean - CAS 8002-43-5 - Calbiochem
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