3-[4-[[[(3-Methylphenyl)amino]carbonyl]amino]-1H-pyrazol-1-yl]-N-(3,4,5-trimethoxyphenyl)-benzamide

1164153-22-3

CAS-Nr.: 1164153-22-3

Englisch Name:: 3-[4-[[[(3-Methylphenyl)amino]carbonyl]amino]-1H-pyrazol-1-yl]-N-(3,4,5-trimethoxyphenyl)-benzamide

Synonyma:: SR-3576;JNK3 Inhibitor XII;SR-3576 >=98% (HPLC);JNK3 Inhibitor XII, SR-3576;JNK3 Inhibitor XII, SR-3576 - CAS 1164153-22-3 - Calbiochem;3-[4-(3-m-Tolyl-ureido)-pyrazol-1-yl]-N-(3,4,5-trimethoxy-phenyl)-benzamide;3-(5-(3-m-Tolylureido)-1H-indazol-1-yl)-N-(3,4,5-trimethoxyphenyl)benzamide;3-[4-[[[(3-Methylphenyl)amino]carbonyl]amino]-1H-pyrazol-1-yl]-N-(3,4,5-trimethoxyphenyl)-benzamide;Benzamide, 3-[4-[[[(3-methylphenyl)amino]carbonyl]amino]-1H-pyrazol-1-yl]-N-(3,4,5-trimethoxyphenyl)-

CBNumber:: CB12750449

Summenformel:: C27H27N5O5

Molgewicht:: 501.53

MOL-Datei:: 1164153-22-3.mol

Request For Quotation

Eigenschaften Sicherheit Verwendungswort Produktionsfirma 40

3-[4-[[[(3-Methylphenyl)amino]carbonyl]amino]-1H-pyrazol-1-yl]-N-(3,4,5-trimethoxyphenyl)-benzamide Eigenschaften

Siedepunkt:: 557.7±50.0 °C(Predicted)

Dichte: 1.27±0.1 g/cm3(Predicted)

storage temp.: 2-8°C

Löslichkeit: DMSO: ≥20mg/mL

Aggregatzustand: powder

pka: 11.51±0.70(Predicted)

Farbe: light brown to brown

Stabilität:: Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.

Sicherheit

WGK Germany	3
HS Code	2933399990

3-[4-[[[(3-Methylphenyl)amino]carbonyl]amino]-1H-pyrazol-1-yl]-N-(3,4,5-trimethoxyphenyl)-benzamide Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

SR 3576 is a JNK-3 selective inhibitor.

Allgemeine Beschreibung

A cell-permeable pyrazolourea compound that acts as a potent, ATP binding pocket-targeting, and JNK3-selective inhibitor (IC₅₀ = 7 nM), inhibiting JNK1 only at much higher concentrations (IC₅₀ = 170 nM) and exhibiting little activity against p38 even at concentrations as high as 20 μM. Shown to inhibit streptozotocin- (Cat. No. 572201) induced c-jun phosphorylation in INS-1 rat β-pancreatic cells (IC₅₀ = 1.3 μM).

Biochem/physiol Actions

SR-3576 is a small molecule inhibitor belonging to aminopyrazole class that selectively inhibits JNK3 with >2800 fold selectively over p38.1

3-[4-[[[(3-Methylphenyl)amino]carbonyl]amino]-1H-pyrazol-1-yl]-N-(3,4,5-trimethoxyphenyl)-benzamide Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

3-[4-[[[(3-Methylphenyl)amino]carbonyl]amino]-1H-pyrazol-1-yl]-N-(3,4,5-trimethoxyphenyl)-benzamide Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 40)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	52927	58
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51471	80
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9709	58
BOC Sciences	--	info@bocsci.com	USA	0	65
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11289	58
Energy Chemical	021-58432009 400-005-6266	marketing1@energy-chemical.com	China	44894	58
MedBioPharmaceutical Technology Inc	021-69568360 18916172912	order@med-bio.cn	China	8141	58
Changzhou Furuisi Biotechnology Co., Ltd	0519-85524369	3477467573@qq.com	China	8618	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24131	58

3-(5-(3-m-Tolylureido)-1H-indazol-1-yl)-N-(3,4,5-trimethoxyphenyl)benzamide
SR-3576
JNK3 Inhibitor XII, SR-3576
3-[4-[[[(3-Methylphenyl)amino]carbonyl]amino]-1H-pyrazol-1-yl]-N-(3,4,5-trimethoxyphenyl)-benzamide
JNK3 Inhibitor XII, SR-3576 - CAS 1164153-22-3 - Calbiochem
3-[4-(3-m-Tolyl-ureido)-pyrazol-1-yl]-N-(3,4,5-trimethoxy-phenyl)-benzamide
JNK3 Inhibitor XII
SR-3576 >=98% (HPLC)
Benzamide, 3-[4-[[[(3-methylphenyl)amino]carbonyl]amino]-1H-pyrazol-1-yl]-N-(3,4,5-trimethoxyphenyl)-
1164153-22-3