Anti-hRYR-2

Anti-hRYR-2 Struktur
CAS-Nr.
Englisch Name:
Anti-hRYR-2
Synonyma:
RYR-2;Anti-RyR2;Anti-RYR-2;Anti-hRYR-2;ryanodine receptor 2;Anti-Ryanodine receptor 2;Anti-RYR2 antibody produced in rabbit;cardiac muscle-type ryanodine receptor;Anti-Cardiac muscle-type ryanodine receptor;cardiac muscle ryanodine receptor-calcium release channel
CBNumber:
CB12884687
Summenformel:
Molgewicht:
0
MOL-Datei:
Mol file

Anti-hRYR-2 Eigenschaften

storage temp. 
-20°C
Aggregatzustand
buffered aqueous glycerol solution

Sicherheit

Anti-hRYR-2 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org)and as a result, are supported by the most extensive characterization in the industry.

The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit .

Allgemeine Beschreibung

RYR2 gene is located at the human chromosome location 1q43. It is majorly expressed in the brain and heart.

Biochem/physiol Actions

RYR2 (ryanodine receptor 2) provides guidance to the release and transport of Ca2+ from sarcoplasmic reticulum (SR) to the cytoplasm during cardiac muscle excitation-contraction (EC) coupling. Protein kinase A (PKA) phosphorylated RYR2 separates (FKBP12.6) to regulate the channel open probability (Po). During the process, a small portion of Ca2+ enter into the cell through the L-type Ca2+ channel, which further activates the RyR2 channel upon membrane depolarization. The activated RyR2 channel releases a large amount of Ca2+ from the SR and subsequent muscle contraction. Missense mutations in this gene cause Kazakh idiopathic ventricular tachycardia and arrhythmogenic right ventricular dysplasia.

Anti-hRYR-2 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Anti-hRYR-2 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 6)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Sigma-Aldrich 021-61415566 800-8193336
orderCN@merckgroup.com China 51471 80
United States Biological --
sales@advtechind.com United States 6106 58

  • Anti-Cardiac muscle ryanodine receptor-calcium release channel
  • Anti-Cardiac muscle-type ryanodine receptor
  • Anti-hRYR-2
  • Anti-Ryanodine receptor 2
  • Anti-RyR2
  • Anti-RYR-2
  • Anti-RYR2 antibody produced in rabbit
  • cardiac muscle ryanodine receptor-calcium release channel
  • cardiac muscle-type ryanodine receptor
  • ryanodine receptor 2
  • RYR-2
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