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ChemicalBook > Produktkatalog >Aromen >Synthetische Düfte >Sauerstoff enthaltende heterocyclische Verbindungen >Thiazole, Thiophene und Pyridine >Benzothiazol

Benzothiazol Produkt Beschreibung

CAS-Nr.95-16-9
Bezeichnung:Benzothiazol
Englisch Name:Benzothiazole
Synonyma:
o-2857;NSC 8040;vangardbt;FEMA 3256;Vangard BT;usafek-4812;USAF ek-4812;Benzthiazole;Benzothiazol;BENZOTHIAZOLE
CBNumber:CB1720657
Summenformel:C7H5NS
Molgewicht:135.19
MOL-Datei:95-16-9.mol
Benzothiazol physikalisch-chemischer Eigenschaften
Schmelzpunkt:: 2 °C(lit.)
Siedepunkt:: 231 °C(lit.)
Dichte: 1.238 g/mL at 25 °C(lit.)
Dampfdichte: 4.66 (vs air)
Dampfdruck: 34 mm Hg ( 131 °C)
Brechungsindex: n20/D 1.642(lit.)
FEMA : 3256 | BENZOTHIAZOLE
Flammpunkt:: >230 °F
storage temp. : Refrigerator
Löslichkeit: 3g/l
Aggregatzustand: Liquid
Farbe: Clear yellow-brown to brown
Explosionsgrenze: 0.9-8.2%(V)
Wasserlöslichkeit: slightly soluble
JECFA Number: 1040
Merck : 14,1107
BRN : 109468
Stabilität:: Stable - regarded as highly persistent in the environment. Incompatible with strong oxidizing agents. Combustion products: nitrogen oxides, carbon monoxide, carbon dioxide, sulphur oxides.
InChIKey: IOJUPLGTWVMSFF-UHFFFAOYSA-N
CAS Datenbank: 95-16-9(CAS DataBase Reference)
NIST chemische Informationen: Benzothiazole(95-16-9)
EPA chemische Informationen: Benzothiazole(95-16-9)
Sicherheit
Kennzeichnung gefährlicher: Xn,T,Xi
R-Sätze:: 22-20/21/22-36-25-24-20
S-Sätze:: 23-26-36-36/37-45
RIDADR : 2810
WGK Germany : 2
RTECS-Nr.: DL0875000
TSCA : Yes
HazardClass : 6.1
PackingGroup : III
HS Code : 29342080
Giftige Stoffe Daten: 95-16-9(Hazardous Substances Data)
Toxizität: LD50 i.v. in mice: 95±3 mg/kg (Domino)

Benzothiazol Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R22:Gesundheitsschädlich beim Verschlucken.
R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut.
S-Sätze Betriebsanweisung:
S23:Gas/Rauch/Dampf/Aerosol nicht einatmen(geeignete Bezeichnung(en) vom Hersteller anzugeben).
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
Beschreibung
Benzothiazole and its derivative are recognized as the most important heterocyclic compounds. This series of compounds is of particular interests. It has various kinds of pharmacological properties and has been included in many kinds of natural products and pharmaceutical agents. The broad spectrum of pharmacological activity in individual benzothiazole derivative enables it to serve as unique and valuable scaffolds for experimental drug design. It is already known that benzothiazole and its derivative has various biological applications including anticancer, antimicrobial, anticonvulsant, antiviral, antidiabetic, antipsychotic, antiinflammatory, analgesic, fungicidal and diuretic. Its derivatives also have many applications in polymer chemistry, dyes, drugs, and silver photography as well as rubber industry.
Chemische Eigenschaften
yellow liquid with an unpleasant odour
Chemische Eigenschaften
Benzothiazole has a delicate, persistent, rose-like odor similar to that of quinoline.
Occurrence
Reported found in apricot, cooked asparagus, mozzarella cheese, skim milk powder, roasted beef, beer, malt whiskey, coconut meat, fresh mango, cooked broccoli and kelp.
Verwenden
Various benzothiazole-benzamides synthesized were evaluated for their analgesic and antidepressant activities.
Verwenden
In organic synthesis.
Definition
ChEBI: An organic heterobicyclic compound that is a fusion product between benzene and thiazole. The parent of the class of benzothiazoles.
synthetische
By refluxing a mixture of zinc o-aminophenylsulfide and formic acid, followed by steam distillation of the alkalized reaction mixture; by heating formanilid or dimethylaniline with sulfur; by oxidation of 2-mercaptobenzothiazole or of the corresponding disulfide.
Aroma threshold values
Detection: 80 to 450 ppb
Taste threshold values
Taste characteristics at 3 ppm: meaty, vegetative, brown, cooked, beefy and coffee-like.
Hazard
Highly toxic by ingestion.
Einzelnachweise
Gupta, Akhilesh, and S. Rawat. "Synthesis and cyclization of benzothiazole." J. of Current Pharmaceutical Research 3.1 (2010): 13-25.
Keri, Rangappa S., et al. "A comprehensive review in current developments of benzothiazole-based molecules in medicinal chemistry." European journal of medicinal chemistry 89 (2015): 207-251.
Khokra, Sukhbir L., et al. "Common methods to synthesize benzothiazole derivatives and their medicinal significance: a review." International Journal of Pharmaceutical Sciences and Research 2.6 (2011): 1356.
Benzothiazol Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Zinksulfid N-Methyl-anilin Benzothiazol-2-thiol Ammoniumnitrat Molybdaendisulfid N,N-Dimethyl-anilin
Downstream Produkte
Benzothiazol-6-amin Dinatrium-2-[4-[[1-[[(2-methoxyphenyl)amino]carbonyl]-2-oxopropyl]azo]-3-sulfonatophenyl]-6-methylbenzothiazol-7-sulfonat 2-[[(1,3-Dihydro-1,3-dimethyl-2H-benzimidazol-2-yliden)methyl]azo]-3-methylbenzothiazoliummethylsulfat
Benzothiazol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.      Global( 220)Lieferanten     
Firmenname Telefon Fax E-Mail Land Produktkatalog Edge Rate
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21910 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693info@tianfuchem.com CHINA 20680 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733sales@mainchem.com CHINA 32457 55
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 20642 58
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 23982 58
Hubei Jusheng Technology Co.,Ltd.
86-188-71490254
peter@hubeijusheng.com CHINA 20094 58
Jinan Finer Chemical Co., Ltd
+86-531-88989536
+86-531-88989539sales@finerchem.com CHINA 939 58
Haihang Industry Co.,Ltd
86-531-88032799
+86 531 8582 1093export@haihangchem.com CHINA 4660 58
Zhengzhou HongSheng Pharmaceutical Co., Ltd. 0371-55695890 0371-55697329
0371-63709726xpkchem@163.com China 4230 58
Shanghai Boyle Chemical Co., Ltd. Mr Qiu:021-50182298(Demestic market) Miss Xu:021-50180596(Abroad market)
+86-21-57758967sales@boylechem.com China 2214 55
 
95-16-9(Benzothiazol)Verwandte Suche:
Thiazol N-Cyclohexylbenzothiazol-2-sulfenamid N,N-Dimethyl-4-(6-methylbenzothiazol-2-yl)anilin 6-Methylbenzothiazol-2-ylamin 2-Methylnaphtho[1,2-d]thiazol 6-Methoxybenzothiazol-2-ylamin Natrium-6-methyl-2-[4-[[2-oxo-1-[(phenylamino)carbonyl]propyl]azo]phenyl]benzothiazol-7-sulfonat Benzothiazol Benzothiazol-2-thiol Di(benzothiazol-2-yl)disulfid 2-Chlorbenzothiazol (2S-cis)-3-Acetoxy-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-onmonohydrochlorid Benzothiazol-2(3H)-on 6-Chlorbenzothiazol-2-ylamin Benzothiazol-2-ylamin
Benzthiazole o-2857 USAF ek-4812 usafek-4812 Vangard BT vangardbt Benzothiazote BENZOTHIAZOLE 96+% Benzothiazole (6CI,8CI,9CI) Benzothiazole,97% 5-Benzothiazole boronic acid pinacol ester Benzothiazole ,99% 2-benzyl-1,3-thiazole 1,3-BENZOTHIAZOLE LABOTEST-BB LT01409601 FEMA NUMBER 3256 FEMA 3256 BENZOTHIAZOLE 1-Thia-3-azaindene Benzosulfonazole Benzothiazol C7H5NS Pharmaceutical Intermediates BENZOTHIAZOLE Sulphur Derivatives Organics Organoborons A-B Alphabetical Listings Flavors and Fragrances Building Blocks Heterocyclic Building Blocks Thiazoles Aromatics C13H16BNO2S -C6H4NCHS C13H18BNO3S C7H5N1S1 Benzo[d]thiazole NSC 8040 Benzothiazole, CP,97% Benzothiazole Vetec(TM) reagent grade, 96% FINE ORGANIC COMPOUND, BENZOTHIAZOLE DERVIATIVE (A3) ,BATCH NUMBER-A11608693 91-16-9 138-59-1 95-16-9 Building Blocks Thiazoles Heterocyclic Building Blocks Heterocycles Sulfur & Selenium Compounds
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