Calcitonin (Lachs)
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- CAS-Nr.
- 47931-85-1
- Bezeichnung:
- Calcitonin (Lachs)
- Englisch Name:
- Calcitonin salmon
- Synonyma:
- tz-ct;SALMON;calcimar;Salcatonin;Salmotonin;Calcitoran;cibacalcin;Salcitonin;Salmon Calcium;Thyrocalcitonin
- CBNumber:
- CB2127316
- Summenformel:
- C145H240N44O48S2
- Molgewicht:
- 3431.85
- MOL-Datei:
- 47931-85-1.mol
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Calcitonin (Lachs) Eigenschaften
- Schmelzpunkt:
- >222oC (dec.)
- Dichte
- 1.54±0.1 g/cm3(Predicted)
- storage temp.
- −20°C
- Löslichkeit
- 0.05 M acetic acid: 1 mg/mL, clear, colorless
- Aggregatzustand
- powder
- Farbe
- White to Off-White
- Wasserlöslichkeit
- Soluble in water at 1mg/ml
- Merck
- 13,1642
- Sequenz
- H-[Cys-Ser-Asn-Leu-Ser-Thr-Cys]-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Gly-Thr-Pro-NH2，(Disulfide bridge: Cys1-Cys7)
- InChIKey
- IYTKRMFJECGBRF-LXQLIYPUSA-N
- CAS Datenbank
- 47931-85-1(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| S-Sätze: |
22-24/25 |
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| WGK Germany |
3 |
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| RTECS-Nr. |
EV8000000 |
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| F |
3-10 |
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| HS Code |
2937190000 |
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| Bildanzeige (GHS) |
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| Alarmwort |
Achtung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H301 |
Giftig bei Verschlucken. |
Akute Toxizität oral |
Kategorie 3 |
Achtung |
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P264, P270, P301+P310, P321, P330,P405, P501 |
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| Sicherheit |
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Calcitonin (Lachs) Chemische Eigenschaften,Einsatz,Produktion Methoden
S-Sätze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
Beschreibung
Calcitonin is a single-chain polypeptide consisting of 32 amino acid residues.
Calcitonins as obtained from different species are identical at seven of the first nine residues,
contain Gly at position 28, and all terminate with Pro-NH2. The C-terminal proline amide (ProNH2) is very important for the biological function of CT, as is the disulfide bridge between Cys
residues at positions 1 and 7. In contrast, the residues from 10 through 27 can be varied and
seem to influence CT's potency as well as its duration of action. Salmon CT differs from human
CT at 16 amino acid residues.
Chemische Eigenschaften
White or almost white powder.
Verwenden
Calcitonin salmon can be used for calcitonin receptor/cAMP assay for assessing the presence of calcitonin receptors expressed by TRAP+ cells.The product can also be used as a test compound for studying as well as comparing the impact of calcitonin gene related peptide (CGRP) and salmon calcitonin (sCT) on gastric mucosal barrier in rats exposed to cold + restraint stress (CRS).
Clinical Use
Only salmon CT is commercially available for medical use, because on a weight basis, it is
approximately 45-fold more potent than human CT. Salmon CT, in parenteral form, is approved
for treating Paget's disease of bone (generally seen in older persons; involves increased bone
resorption and softening of bones), postmenopausal osteoporosis, and hypercalcemia of malignancy
(multiple myeloma or advanced breast carcinoma). Salmon CT also is available in a nasal spray
formulation, which is used exclusively in the treatment of postmenopausal osteoporosis.
Calcitonin (Lachs) Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Calcitonin (Lachs) Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 385)Lieferanten
47931-85-1(Calcitonin (Lachs))Verwandte Suche:
- salmoncalcitonin-(i-32)
- salmoncalcitonini
- tz-ct
- Salmon Calcitonin Acetate
- Salcatonin
- CalcitoninAcetate
- Salmon Calcium
- M.W. 3431.90 C145H240N44O48S2
- Calcitoran
- Salmotonin
- Calcitonin Acetate,form Salmon
- H-[Cys-Ser-Asn-Leu-Ser-Thr-Cys]-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Gly-Thr-Pro-NH2
- Thyrocalcitonin
- Salcitonin Acetate
- calcimar
- cibacalcin
- salmoncalcitonin
- CALCITONIN, SALMON
- CALCITONIN (SALMON I)
- CSNLSTCVLGKLSQELHKLQTYPRTNTGSGTP-NH2
- CSNLSTCVLGKLSQELHKLQTYPRTNTGSGTP-NH2 (DISULFIDE BRIDGE: 1-7)
- CYS-SER-ASN-LEU-SER-THR-CYS-VAL-LEU-GLY-LYS-LEU-SER-GLN-GLU-LEU-HIS-LYS-LEU-GLN-THR-TYR-PRO-ARG-THR-ASN-THR-GLY-SER-GLY-THR-PRO-NH2
- CYS-SER-ASN-LEU-SER-THR-CYS-VAL-LEU-GLY-LYS-LEU-SER-GLN-GLU-LEU-HIS-LYS-LEU-GLN-THR-TYR-PRO-ARG-THR-ASN-THR-GLY-SER-GLY-THR-PRO-NH2 SALMON
- H-CYS-SER-ASN-LEU-SER-THR-CYS-VAL-LEU-GLY-LYS-LEU-SER-GLN-GLU-LEU-HIS-LYS-LEU-GLN-THR-TYR-PRO-ARG-THR-ASN-THR-GLY-SER-GLY-THR-PRO-NH2
- H-CYS-SER-ASN-LEU-SER-THR-CYS-VAL-LEU-GLY-LYS-LEU-SER-GLN-GLU-LEU-HIS-LYS-LEU-GLN-THR-TYR-PRO-ARG-THR-ASN-THR-GLY-SER-GLY-THR-PRO-NH2 (DISULFIDE BRIDGE: 1-7)
- H-CYS-SER-ASN-LEU-SER-THR-CYS-VAL-LEU-GLY-LYS-LEU-SER-GLN-GLU-LEU-HIS-LYS-LEU-GLN-THR-TYR-PRO-ARG-THR-ASN-THR-GLY-SER-GLY-THR-PRO-NH2, (DISULFIDE BOND)
- THYROCALCITONIN SALMON
- SALMON
- CYS-SER-ASN-LEU-SER-THR-CYS-VAL-LEU-GLY-LYS-LEU-SER-GLN-GLU-LEU-HIS-LYS-LEU-GLN-THR-TYR-PRO-ARG-THR-ASN-THR-GLY-SER-GLY-THR-PRO-NH2(DISULFIDE BRIDGE CYS1-CYS7)
- Salcitonin
- Calcitonin Salmon (20 mg) (COLD SHIPMENT REQUIRED)
- Salcitonin Acetate(SalMon Calcitonin)
- Salcatonin, SalMon Calcitonin, Thyrocalcitonin (salMon)
- SalMon Calcitonin Aceta
- H-CYS-SER-ASN-LEU-SER-THR-CYS-VAL-LEU-
- Calcitonin (salMon) xAcetate
- H-Cys-Ser-Asn-Leu-Ser-Thr-Cys-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Gly-Thr-Pro-NH2 acetate salt (Disulfide bond)
- Salcitonin/Calcitonin
- Calcitonin(Salmone) Acetate
- Calcitonin salmon Acetate
- Calcitonin, salmon synthetic
- CALCITONIN SALMON 250 UG
- Salmon Calcitonin Acetate, ≥97% (HPLC)
- Salcatonin for Injection
- Calcitonin Salmon RS
- Calcitonin?(Salmon) impurity
- Cyclic (1→7)-disulfide L-Cysteinyl-L-seryl-L-asparaginyl-L-leucyl-L-seryl-L-threonyl-L-cysteinyl-L-valyl-L-leucylglycyl-L-lysyl-L-leucyl-L-seryl-L-glutaminyl-L-α-glutamyl-L-leucyl-L-histidyl-L-lysyl-L-leucyl-L-glutaminyl-L-threonyl-L-tyros
- Salmon calcitonin USP/EP/BP
- Calcitonin salmon USP/EP/BP
- Salcatonin，Calcitonin (Salmon)
- Calcitonin (salmon) (C0200000)
- Calcitonin Salmon (COLD SHIPMENT REQUIRED) (1086200)
- Calcitonin salmon/Thyrocalcitonin
- Salmon Calcitonin Impurities
- Calcitonin Salmon (40 mg) (COLD SHIPMENT REQUIRED)
- 47931-85-1
- C145H240N44O48S2
- Cell Biology
