ChemicalBook
Chinese english Germany Japanese Korea

Rescinnamin Produkt Beschreibung

RESCINNAMINE Struktur
24815-24-5
CAS-Nr.
24815-24-5
Bezeichnung:
Rescinnamin
Englisch Name:
RESCINNAMINE
Synonyma:
Rozex;Apolon;Rescin;Tuareg;ANAPREL;Anapral;Cartric;Moderil;Resipal;Apoterin
CBNumber:
CB2344278
Summenformel:
C35H42N2O9
Molgewicht:
634.73
MOL-Datei:
24815-24-5.mol

Rescinnamin Eigenschaften

Schmelzpunkt:
238-239°C
alpha 
D24 -97° (c = 1 in chloroform)
Siedepunkt:
669.26°C (rough estimate)
Dichte
1.2161 (rough estimate)
Brechungsindex
1.5300 (estimate)
storage temp. 
2-8°C
pka
pKa 6.4 (Uncertain)
Stabilität:
Stable, but darkens slowly in light. Incompatible with strong oxidizing agents.
CAS Datenbank
24815-24-5
EPA chemische Informationen
Rescinnamine (24815-24-5)

Sicherheit

Kennzeichnung gefährlicher Xn
R-Sätze: 25-20/21/22
S-Sätze: 22-45-36
RIDADR  1544
HazardClass  6.1(b)
PackingGroup  III
Giftige Stoffe Daten 24815-24-5(Hazardous Substances Data)

Rescinnamin Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:

R25:Giftig beim Verschlucken.

S-Sätze Betriebsanweisung:

S22:Staub nicht einatmen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).

Beschreibung

This Rauwolfia alkaloid is found in the barks of R. serpentina and R. vomitora and was originally given the name Reserpinine, this being altered to avoid confusion with another alkaloid of the same name (q.v.). The base has [α]17D - 99.2° (c 1.3, CHCI3). From chemical degradation and spectroscopic analysis, the structure has been established as the 3:4: 5-trimethoxycinnamoyl ester of reserpic acid.

Chemische Eigenschaften

white to cream powder

Verwenden

Rescinnamine is an angiotensin-converting enzyme inhibitor used as an antihypertensive drug.

Verwenden

Rescinnamine occurs in the roots of a num ber of Rauwolfia species. Therapeutically, itis used as an antihypertensive agent.

Trademarks

Moderil (Pfizer).

Allgemeine Beschreibung

Odorless white to cream colored crystalline powder.

Air & Water Reaktionen

Insoluble in water.

Reaktivität anzeigen

The neat material darkens slowly on exposure to light. In solution this occurs more rapidly. .

Health Hazard

The pharmacological properties of rescinnamine are similar to those of reserpine, butthe side effects are low. It acts as a sedativeand hypotensive. A dose of 0.25 mg/day mayproduce the effect of sleepiness in humans.Excessive doses may produce depression,nightmare, nausea, diarrhea, and hypotension.
LD50 value, oral (rats): 1000 mg/kg
The carcinogenicity of rescinnamine inanimals or humans is unknown.

Brandgefahr

Flash point data for RESCINNAMINE are not available. RESCINNAMINE is probably combustible.

läuterung methode

Crystallise it from *benzene, MeOH or aqueous Me2CO. The hydrochloride has m 232o(dec) (from MeOH) and [] D -74o (MeOH). It is an antihypertensive. [Klohs et al. J Am Chem Soc 77 2241 1955, Beilstein 25 III/IV 1323.]

Einzelnachweise

Haack e tal., Naturwiss., 41, 214 (1954)
Klohs, Draper, Keller.,J. Amer. Chem. Soc., 77,2241 (1955)
Kidd., Chem. & Ind., 1481 (1955)
Popelak, Lettenbauer., Arch. Pharm., 296,261 (1963)

Rescinnamin Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Rescinnamin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 61)Lieferanten
Firmenname Telefon Fax E-Mail Land Produktkatalog Edge Rate
Hubei Jusheng Technology Co.,Ltd.
86-18871470254
027-59599243 linda@hubeijusheng.com CHINA 28229 58
HENAN BON INDUSTRIAL CO.,LTD
0371-55170695
info@hnbon.com CHINA 26742 58
Dideu Industries Group Limited
029-88380327
Service@dideu.com CHINA 30014 58
Beijing HuaMeiHuLiBiological Chemical 010-56205725
010-65763397 waley188@sohu.com China 12341 58
Nanjing Sunlida Biological Technology Co., Ltd. 025-57798810-
025-57019371 sales@sunlidabio.com;sales@sunlidabio.com China 3756 55
Sichuan Wei Keqi Biological Technology Co., Ltd. 18116577057 028-81700200-
028-81705658 2851167785@qq.com China 4725 56
Wuxi Zhongkun Biochemical Technology Co., Ltd. 18013409632
051085625359 sales@reading-chemicals.com; China 15200 58
Wuhan ChemFaces Biochemical Co., Ltd. 15172504745 027-84237683-
+86-27-84254680 aileen@chemfaces.com China 7235 55
EMMX Biotechnology LLC 888-539-0666
888-539-0666 info@emmx.com United States 8454 60
Shanghai YuanYe Biotechnology Co., Ltd. 18572826883 021-61312824-
QQ:3008007432 3008007432@qq.com China 30311 60

24815-24-5(Rescinnamin)Verwandte Suche:


  • Yohimban-16-carboxylic acid, 11,17-dimethoxy-18-[[(2E)-1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propen-1-yl]oxy]-, methyl ester, (3β,16β,17α,18β,20α)-
  • METHYL RESERPATE-3,4,5-TRIMETHOXY CINNAMIC ACID ESTER
  • ANAPREL
  • 3,4,5-TRIMETHOXYCINNAMOYLRESERPATE
  • 17alpha-dimethoxy-18beta-((1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propenyl)oxy)-1
  • 3,4,5-Trimethoxycinnamic acid, methyl reserpate
  • 3,4,5-Trimethoxycinnamoyl methyl reserpate
  • 3,4,5-trimethoxycinnamoylmethylreserpate
  • 3,4,5-Trimethylcinnamic acid, ester with methyl reserpate
  • 3,4,5-trimethylcinnamicacid,esterwithmethylreserpate
  • 3,4,5-Trimethylcinnamoyl methyl reserpate
  • 3,4,5-trimethylcinnamoylmethylreserpate
  • 3beta,20alpha-Yohimban-16beta-carboxylic acid, 18beta-hydroxy-11,17alpha-dimethoxy-, methyl ester, 3,4,5-trimethoxycinnamate (ester)
  • 3-beta,20-alpha-Yohimban-16-beta-carboxylic acid, 18-beta-hydroxy-11,17-alpha-dimethoxy-,methyl ester, 3,4,5-trimethoxycinnamate
  • 3beta,20alpha-yohimban-16beta-carboxylicacid,18beta-hydroxy-11,17alpha-dimeth
  • 3beta,20alpha-yohimban-16beta-carboxylicacidmethylester
  • Anapral
  • Apolon
  • Apoterin
  • Apoterin S
  • Benz(g)indolo(2,3-a)quinolizine-1-carboxylic acid, 1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydro-3-hydroxy-2,11-dimethoxy-, methyl ester, 3,4,5-trimethoxycinnamate
  • Cartric
  • Cinamine
  • Cinatabs
  • Cinnaloid
  • Cinnasil
  • imethoxy-,methylester,3,4,5-trimethoxycinnamate(ester)
  • Methyl 11,17-dimethoxy-18-([(2E)-3-(3,4,5-trimethoxyphenyl)-2-propenoyl]oxy)yohimban-16-carboxylate
  • Methyl 18beta-hydroxy-11,17alpha-dimethoxy-3beta,20alpha-yohimban-16beta-carboxylate
  • Methyl 18-O-(3,4,5-trimethoxycinnamoyl)reserpate
  • Methyl trimethoxycinnamoylreserpate
  • methyl18-o-(3,4,5-trimethoxycinnamoyl)reserpate
  • methyl18-o-(3,4,5-trimethoxycinnamoylreserpate
  • methylester,3,4,5-trimethoxycinnamate(ester),(e)-oxy
  • methyltrimethoxycinnamoylreserpate
  • Moderil
  • Normorescina
  • Paresinan
  • Raupyrol
  • Raurescin
  • Raurescine
  • Recinnamine
  • Recitensina
  • Rescaloid
  • Rescamin
  • Rescidan
  • Rescin
  • Rescinnamin
  • Rescinpal
  • Rescisan
  • Rescitens
  • Resealoid
  • resepinine(c35alkaloid)
  • Reserpinene
  • Reserpinin
  • Reserpinine (C35 alkaloid)
  • reserpinine[c35alkaloid]
  • Resipal
Copyright 2019 © ChemicalBook. All rights reserved