PHENAMIL

2038-35-9

CAS-Nr.: 2038-35-9

Englisch Name:: PHENAMIL

Synonyma:: PHENAMIL;phenylamil;phenamil methanesulfonate salt;Phenamil methanesulfonate (free base);3,5-diamino-N-[amino(anilino)methylene]-6-chloro-pyrazinamide;3,5-DIAMINO-6-CHLORO-N-[IMINO(PHENYLAMINO)METHYL]-PYRAZINECAR-BOXAMIDE;3,5-Diamino-6-chloro-N-[imino(phenylamino)methyl]pyrazine-2-carboxamide;3,5-diamino-N-[amino(anilino)methylidene]-6-chloropyrazine-2-carboxamide;2-Pyrazinecarboxamide, 3,5-diamino-6-chloro-N-[imino(phenylamino)methyl]-;3,5-bis(azanyl)-N-[azanyl-(phenylamino)methylidene]-6-chloro-pyrazine-2-carboxamide

CBNumber:: CB2384179

Summenformel:: C12H12ClN7O

Molgewicht:: 305.72

MOL-Datei:: 2038-35-9.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 28

PHENAMIL Eigenschaften

Schmelzpunkt:: >181°C (dec.)

Dichte: 1.65±0.1 g/cm3(Predicted)

storage temp.: 2-8°C

Löslichkeit: DMSO: >15 mg/mL

Aggregatzustand: solid

pka: 8.10±0.46(Predicted)

Farbe: yellow

Sicherheit

WGK Germany	3

PHENAMIL Chemische Eigenschaften,Einsatz,Produktion Methoden

Enzyminhibitor

This amiloride derivative (FW = 306.73 g/mol; CAS 2038-35-9), also known as 3,5-diamino-6-chloro-N-[imino(phenylamino)methyl]pyrazine carboxamide, irreversibly inhibits amiloride-sensitive Na+ channels. It is often supplied commercially as the methanesulfonate salt. Na+ channel blockers, such as phenamil and benzamil, are be alsoing explored as a way to counteract the hyperabsorption of NaCl in cystic fibrosis airways. Target(s): diamine oxidase; Na+ channels; and Na+ -driven flagellar motility.

PHENAMIL Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

PHENAMIL Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 28)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	96815	76
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15848	69
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9709	58
Jinan Yaoyan Pharmaceutical Co., Ltd.		jnyaoyan@163.com	China	3069	58
Shenzhen Polymeri Biochemical Technology Co., Ltd.	+86-400-002-6226 13028896684	sales@rrkchem.com	China	55591	58
Nanjing Meihao Pharmaceutical Technology Co., Ltd.	meitaochem@126.com	meitaochem@126.com	China	19105	58
Changzhou Furuisi Biotechnology Co., Ltd	0519-85524369	3477467573@qq.com	China	8618	58

PHENAMIL
3,5-DIAMINO-6-CHLORO-N-[IMINO(PHENYLAMINO)METHYL]-PYRAZINECAR-BOXAMIDE
3,5-diamino-6-chloro-n-[imino(phenylamino)methyl]pyrazinecarboxamide methanesulfonate salt
phenamil methanesulfonate salt
phenylamil
3,5-Diamino-6-chloro-N-[imino(phenylamino)methyl]pyrazine-2-carboxamide
3,5-bis(azanyl)-N-[azanyl-(phenylamino)methylidene]-6-chloro-pyrazine-2-carboxamide
3,5-diamino-N-[amino(anilino)methylene]-6-chloro-pyrazinamide
3,5-diamino-N-[amino(anilino)methylidene]-6-chloropyrazine-2-carboxamide
Phenamil methanesulfonate (free base)
2-Pyrazinecarboxamide, 3,5-diamino-6-chloro-N-[imino(phenylamino)methyl]-
2038-35-9
C12H12ClN7OCH3SO3H
C12H12ClN7O
Irreversible inhibitor of amiloride-sensitive Na+ channels; derivative of amiloride.
Cell Biology
Cell Signaling and Neuroscience
BioChemical
Amiloride and Derivatives
Monovalent Ion Channels
Ion Channels
Sodium Channel Modulators
Voltage-gated Ion Channels