CYCLIC-PIFITHRIN-ALPHA

60477-34-1

CAS-Nr.: 60477-34-1

Englisch Name:: CYCLIC-PIFITHRIN-ALPHA

Synonyma:: Pifithrin-2;Pifithrin-alpha (cyclic) . HBr;Pifithrin-β (QB-102 and Cyclic-Pifithrin-α);Pifithrin-α, Cyclic- - CAS 60477-34-1 - Calbiochem;2-(p-Tolyl)-5,6,7,8-tetrahydrobenzo[d]imidazo[2,1-b]thiazole;5,6,7,8-Tetrahydro-2-(4-methylphenyl)-imidazo[2,1-b]benzothiazole;Imidazo[2,1-b]benzothiazole, 5,6,7,8-tetrahydro-2-(4-methylphenyl)-

CBNumber:: CB2504209

Summenformel:: C16H16N2S

Molgewicht:: 268.38

MOL-Datei:: 60477-34-1.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 28

CYCLIC-PIFITHRIN-ALPHA Eigenschaften

Schmelzpunkt:: 266.4-267.3 °C(lit.)

Dichte: 1.30±0.1 g/cm3(Predicted)

storage temp.: −20°C

Löslichkeit: DMSO: 20 mg/mL

Aggregatzustand: White solid

pka: 6.75±0.20(Predicted)

Sicherheit

WGK Germany	3

CYCLIC-PIFITHRIN-ALPHA Chemische Eigenschaften,Einsatz,Produktion Methoden

Allgemeine Beschreibung

A cell-permeable and very stable analog of Pifithrin-α (Cat. No. 506132), with similar biological function, but with reduced cytotoxicity. A chemical inhibitor of p53. Reversibly inhibits p53-dependent transactivation of p53-responsive genes; also reversibly blocks p53-mediated apoptosis. Acts as a P-gp modulator by changing relative substrate specificity of the transporter. This compound has been reported to be a potent STAT6 transcriptional inhibitor.

Biochem/physiol Actions

Cell permeable: yes

CYCLIC-PIFITHRIN-ALPHA Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

CYCLIC-PIFITHRIN-ALPHA Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 28)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Career Henan Chemica Co	+86-0371-86658258 15093356674;	laboratory@coreychem.com	China	30255	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131981	58
Shanghai Boyle Chemical Co., Ltd.		sales@boylechem.com	China	2923	55
MedChemexpress LLC	021-58955995	sales@medchemexpress.cn	United States	4863	58
Shanghai Tauto Biotech Co., Ltd.	021-51320588	tauto@tautobiotech.com	China	3989	66
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51471	80
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9709	58

Pifithrin-alpha (cyclic) . HBr
5,6,7,8-Tetrahydro-2-(4-methylphenyl)-imidazo[2,1-b]benzothiazole
Pifithrin-α, Cyclic- - CAS 60477-34-1 - Calbiochem
Pifithrin-2
Imidazo[2,1-b]benzothiazole, 5,6,7,8-tetrahydro-2-(4-methylphenyl)-
Pifithrin-β (QB-102 and Cyclic-Pifithrin-α)
2-(p-Tolyl)-5,6,7,8-tetrahydrobenzo[d]imidazo[2,1-b]thiazole
60477-34-1