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Eisen(II)fumarat Produkt Beschreibung

Ferrous fumarate Struktur
141-01-5
CAS-Nr.
141-01-5
Bezeichnung:
Eisen(II)fumarat
Englisch Name:
Ferrous fumarate
Synonyma:
firon;fumar;ircon;galfer;cpiron;ferrone;fumafer;fumar-f;hemoton;palafer
CBNumber:
CB2739933
Summenformel:
C4H2FeO4
Molgewicht:
169.9
MOL-Datei:
141-01-5.mol

Eisen(II)fumarat Eigenschaften

Schmelzpunkt:
>280°C
Dichte
2.435
Löslichkeit
Slightly soluble in water, very slightly soluble in ethanol (96 per cent).
Aggregatzustand
solid
Wasserlöslichkeit
Soluble in water (0.14 g/100 ml at 25°C).
Merck 
14,4046
Stabilität:
Stability
InChIKey
PMVSDNDAUGGCCE-TYYBGVCCSA-L
CAS Datenbank
141-01-5(CAS DataBase Reference)
EPA chemische Informationen
2-Butenedioic acid (2E)-, iron(2+) salt (1:1) (141-01-5)

Sicherheit

R-Sätze: 36/37/38
S-Sätze: 22-36/37/39-24/25
WGK Germany  2
RTECS-Nr. LT1950000
TSCA  Yes
HS Code  29171900
Toxizität LD50 in mice, rats (mg Fe/kg): 630, 580 orally (Berenbaum)

Eisen(II)fumarat Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:

R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.

S-Sätze Betriebsanweisung:

S22:Staub nicht einatmen.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.

Beschreibung

Ferrous fumarate is the ferrous salt form of fumarate. One of its most important applications is being used as iron supplements for the treatment of iron deficiency and anemia. It has been demonstrated that application of ferrous sulfate drops or a single daily dose of microencapsulated ferrous fumarate sprinkles plus ascorbic acid both result in successful treatment of anemia without remarkable side effects. However, recent studies have also shown that compared to other iron supplements, ferrous fumarate has a highest rate of inducing adverse reactions such as erosive mucosal injury in the gastrointestinal tract as well as nausea, vomiting and epigastric discomfort.

Chemische Eigenschaften

§184.1307d(a) Ferrous fumarate (iron(II)fumarate, C4H2Fe04) is an odorless, reddish-orange to reddish-brown powder. It may contain soft lumps that produce a yellow streak when crushed. It is prepared by admixing hot solutions of ferrous sulfate and sodium fumarate.

Chemische Eigenschaften

brown to reddish-brown powder

Originator

Toleron,Mallinckrodt Inc.,US,1957

Verwenden

Ferrous Fumarate is a reddish orange to red-brown powder that is a source of iron. it has high bioavailability and can be used in foods where the red color can be masked. it contains approximately 33% iron. it is used as a dietary supplement in breakfast cereals, poultry stuffing, enriched flour, and instant drinks.

Verwenden

Ferrous fumarate is available as a syrup and may be useful in small children for the treatment and prophylaxis of iron deficiency.

Definition

Anhydrous salt of a combination of ferrous iron and fumaric acid, stable, odorless, substantially tasteless. Reddish-brown, anhydrous powder, contains 33% iron by weight, does not melt at temperatures up to 280C, insoluble in alcohol, very slightly solubl

Manufacturing Process

Sodium carbonate (53.5 pounds of Na2CO3-H2O) was dissolved in water (40 to 45 gallons) and fumaric acid (50 pounds) was added slowly. During the addition the solution was stirred and heated. The resulting solution of sodium fumarate, having a pH of 6.8, was added slowly with mixing to a solution of ferrous sulfate (118 pounds FeSO4-7H2O in 33 gallons of water) having a pH of 3.3, both solutions being maintained at or near boiling temperature during the mixing. The resulting slurry of reddish-brown anhydrous ferrous fumarate was filtered and washed in a centrifuge and dried in a tray drier (15 hours at 110°C). Yield: 63 pounds, 86% of theory. Calculated for FeC4H2O4: Fe, 32.9%. Found: Fe, 32.6%. Only 0.2% of ferric iron (Fe+++) was found.

Therapeutic Function

Hematinic

Sicherheitsprofil

Poison by intraperitoneal route. Moderately toxic by ingestion and subcutaneous routes. Human systemic effects by ingestion: dyspnea, nausea or vomiting, somnolence. When heated to decomposition it emits acrid smoke and irritating fumes. See also FUMRIC ACID.

Einzelnachweise

Zlotkin, Stanley, et al. "Treatment of anemia with microencapsulated ferrous fumarate plus ascorbic acid supplied as sprinkles to complementary (weaning) foods." The American journal of clinical nutrition 74.6 (2001): 791-795.
Cancelo-Hidalgo, María Jesús, et al. "Tolerability of different oral iron supplements: a systematic review." Current medical research and opinion 29.4 (2013): 291-303.

Eisen(II)fumarat Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Eisen(II)fumarat Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 300)Lieferanten
Firmenname Telefon Fax E-Mail Land Produktkatalog Edge Rate
Target Molecule Corp
18019718960 781-999-5354
marketing@targetmol.com United States 19232 58
Henan DaKen Chemical CO.,LTD.
+86-371-66670886
info@dakenchem.com China 21031 58
Jiangsu Kolod Food Ingredients Co.,Ltd.
+8618805133257 +86-518-85110578 18805133257
+86-518-85110578 sales3257@jskolod.com China 126 60
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 22607 55
Hangzhou FandaChem Co.,Ltd.
008615858145714
+86-571-56059825 fandachem@gmail.com CHINA 8882 55
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418684 18949823763
86-0551-65418684 info@tnjchem.com China 3001 55
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 29960 58
SHANDONG ZHI SHANG CHEMICAL CO.LTD
+86 18953170293
+86 0531-67809011 sales@sdzschem.com CHINA 2858 58
Hubei Jusheng Technology Co.,Ltd.
86-18871470254
027-59599243 linda@hubeijusheng.com CHINA 28229 58
Hebei Guanlang Biotechnology Co., Ltd.
+8619930503282
sales3@crovellbio.com China 5460 58

141-01-5(Eisen(II)fumarat)Verwandte Suche:


  • Iron(Ⅱ) fumarate
  • Iron(II) fuMarate >=97.0%
  • IR microencapsulated Ferrous fumarate
  • Ferrius fumarate
  • IRON(II) FUMARATE
  • IRON(+2)FUMARATE
  • IRON FUMARATE
  • FERROUS FUMARATE
  • FERROUS FUMERATE
  • ferrofume
  • ferronat
  • ferrone
  • ferrotemp
  • Ferroustrans-butenedioicacid
  • fersamal
  • Fersanmal
  • firon
  • fumafer
  • fumar
  • fumar-f
  • fumaricacid,iron(2+)salt(1:1)
  • galfer
  • hemoton
  • ircon
  • iron(2+)salt(1:1)
  • iron(2++)salt(1:1)
  • one-iron
  • palafer
  • toleron
  • tolferain
  • (E)-2-Butenedioic acid iron(II) salt
  • 2-Butenedioicacid(E)-,iron(2+)salt(1:1)
  • cpiron
  • erco-fer
  • ercoferro
  • feostat
  • feroton
  • tolifer
  • FERROUS FUMARATE USP
  • FerrousFumrate
  • Ferrous fumarate (non-medicinal)
  • Iron(II) fumarate (non-medicinal)
  • 2-Butenedioic acid (2E)-, iron(2+) salt (1:1)
  • FERROUSFUMARATE,FCC
  • 2-Butenedioic acid (E)-,iron(2+) salt
  • 2-Butenedioic acid (2E)-, iron(2+) salt
  • Orgasal
  • (E)-2-Butenedioic acid iron(II)
  • Iron (II) fumarate, USP, (L-A093)
  • Eisen(II)fumarate
  • Iron Fumarate fandachem
  • Ferrosi Fumaras
  • Ferrous fumarate USP/EP/BP
  • 141-01-5
  • C4H2FeO4
  • C4H4O4Fe
  • Pharmaceutical intermediates
  • Pharmacopoeia (USP)
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