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3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride

3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride Struktur
762240-92-6
CAS-Nr.
762240-92-6
Englisch Name:
3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride
Synonyma:
Sitagliptin hydrochloride;3-(trifluoromethyl)-5,6,7,8-tetrahydro;Sitagliptin Triazole Hydrochloride;3-(TRIFLUOROMETHYL)-5,6,7,8- TETRAHYDRO[1,2,4]TRIAZOLO[4,3-;3-(Trifluoromethyl)-5;Sitagliptin interMediate A;3-trifluoro Methyl-[1,2,4]triazole[4,3-a]piperazine hydrochloride;3-(Trifluoromethyl)-5 6 7 8-tetrahydro-1 2 4triazolo4 3-apyrazine hydroch;5,6,7,8-Tetrahydro-3-(trifluormethyl)-[4,3-a]-1,2,4-triazolopyrazine hydrochloride;5,6,7,8-Tetrahydro-3-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyrazine hydrochloride 98%
CBNumber:
CB31228965
Summenformel:
C6H7F3N4.ClH
Molgewicht:
228.6
MOL-Datei:
762240-92-6.mol
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3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride Eigenschaften

Schmelzpunkt:
236-246°C
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
Löslichkeit
DMSO (Slightly), Methanol (Slightly)
Aggregatzustand
Solid
Farbe
White to Off-White
InChI
InChI=1S/C6H7F3N4.ClH/c7-6(8,9)5-12-11-4-3-10-1-2-13(4)5;/h10H,1-3H2;1H
InChIKey
AQCSCRYRCRORET-UHFFFAOYSA-N
SMILES
C12=NN=C(C(F)(F)F)N1CCNC2.[H]Cl
CAS Datenbank
762240-92-6(CAS DataBase Reference)
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
Kennzeichnung gefährlicher T
R-Sätze: 25
S-Sätze: 45
RIDADR  UN2811
HS Code  2933599577
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizität (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P261 Einatmen von Staub vermeiden.
P304+P340 BEI EINATMEN: Die Person an die frische Luft bringen und für ungehinderte Atmung sorgen.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.
P405 Unter Verschluss aufbewahren.

3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride is a pharmaceutical intermediate compound used in the preparation of Sitagliptin phosphate. Sitagliptin is an oral hypoglycaemic agent, a dipeptidyl peptidase-4 inhibitor, which is used in the treatment of type 2 diabetes.

Chemische Eigenschaften

White Solid or White to Light yellow powder to crystal

3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Sitagliptin N-Boc IMpurity

3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 575)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
JUYE XIANDAI fine chemistry Co.,Ltd 		+8618958038633
 tony@sdhypharma.com China 58 58
Wuhan BJM Pharm Inc
+86-027-5234-1919 +8613545198479
 sales03@benjaminpharmchem.com China 671 58
Hebei Yanxi Chemical Co., Ltd. 		+8617531190177
 peter@yan-xi.com China 5993 58
Shandong Huisheng Import & Export Co., Ltd. 		+86-13176845580 +86-13176845580
 da@zhongda-biotech.com China 248 58
Anhui Zhongda Biotechnology Co., Ltd 		+8619956560829
 justine@zhongda-biotech.com China 300 58
Anhui Zhongda Biotechnology Co., Ltd 		+8615689548120
 linda@zhongda-biotech.com China 204 58
Anhui Ruihan Technology Co., Ltd 		+8617756083858
 daisy@anhuiruihan.com China 994 58
Capot Chemical Co.,Ltd. 		571-85586718 +8613336195806
 sales@capotchem.com China 29797 60
Beijing Cooperate Pharmaceutical Co.,Ltd 		010-60279497
sales01@cooperate-pharm.com CHINA 1811 55
Hi-Tech Chemistry Corp 		0519-86626038
yuhh@hitechem.com CHINA 811 58

762240-92-6()Verwandte Suche:

Prazosin 2-Methyl-pyrazin 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)4-[(tetrahydro-2-furanyl)carbonyl]piperazine hydrochloride Terazosin [4-(4-Amino-6,7-dimethoxy-quinazolin-2- yl)piperazin-1-yl]-(2,5-dioxabi cyclo[4.4.0]deca-6,8,10-trien-4-yl)methanone 2,3,5,6-Tetramethyl-pyrazin D-Cysteinhydrochlorid Cilastatin Ethyl-7-chlor-2-oxoheptanoat 1-Brom-5-chlorpentan Natrium octadecylfumarat 2,2-Dimethyl-1,3-dioxan-4,6-dion 1,1-Dichlorethen 2,4-Difluorphenylessigsure Ethyltrifluoracetat 3,4-Difluorphenylessigsure Trifluoromethyl
  • 1,2,4-Triazolo[4,3-a]pyrazine,5,6,7,8-tetrahydro-3-(trifluoroMethyl)-,hydrochloride(1:1)
  • 3 - (three fluorinated Methyl) - 5,6,7,8 - four hydrogen - triazole 4-trichlorobenzene [1] and [4, 3 - alpha] pyrazine hydrochloride
  • Sitagliptin side chain
  • 3-CF3-5,6,7,8-H4-[1,2,4]triazolo[4,3a]pyrazine HCl
  • Triazolepine hydrochloride
  • 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-α]pyrazine Hydrochloride
  • 5,6,7,8-Tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-α]pyrazine Monohydrochloride
  • 5,6,7,8-Tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine Monohydrochloride
  • 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochlorid
  • 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride
  • 3-(trifluoromethyl)-5,6,7,8-retrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride
  • 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-1,2,4-triazolo-[4,3-a]pyrazine HCl
  • 3-(TrifluoroMethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyr
  • 5,6,7,8-Tetrahydro-3-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyrazine hydrochloride
  • 3-(trifluoroMethyl)-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride
  • 5,8-dimethyl-3-(trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine
  • Sitagliptin Intermediate 2
  • 1,2,4-Triazolo[4,3-a]pyrazine, 5,6,7,8-tetrahydro-3-(trifluoroMethyl)-, hydrochloride
  • Sitagliptin Impurity 64
  • Sitagliptin Intermediates Impurity
  • 3-a]pyrazine hydrochloride
  • Sitagliptin Impurity 20 HCl
  • 3-(trifluoromethyl)-5,6,7,8-r
  • Sitagliptin Triazole Impurity HCl
  • Sitagliptin-16
  • Sitagliptin Triazole (Impurity C)
  • Sitaglliptin phosphate intermediate
  • 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride （Sitagliptin）
  • Sitagliptin triazole impurity hydrochloride
  • 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo [4,3-a]pyrazine hydrochloride [TTTP]
  • pyrazine HCl
  • Cas762240-92-6 3-trifluoro Methyl-[1,2,4]triazole[4,3-a]piperazine Hydrochloride
  • Sitagliptin Impurity 20 Hydrochloride
  • Urgent?
  • 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride ISO 9001：2015 REACH
  • 3-(trifluoromethyl)-5,6,7, 8-tetrahydro-[1,2,4] triazolio [4,3-a] pyrazine
  • 3-(terifluoromethyl)-7-[(2,4,5-trifluorophenyl]acetyl]-5,6,7,8- tetrahydro[1,2,4]triazole[4,3-a]pyrazine
  • Sitagliptin Triazole HCL
  • 3-trifluoro methyl-[1,2,4]triazole[4,3-a]piperazine hydrochl...
  • 3-(TRIFLUOROMETHYL)-5,6,7,8- TETRAHYDRO[1,2,4]TRIAZOLO[4,3-
  • 3-trifluoro Methyl-[1,2,4]triazole[4,3-a]piperazine hydrochloride
  • Sitagliptin Triazole Hydrochloride
  • 5,6,7,8-Tetrahydro-3-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyrazine hydrochloride 98%
  • Sitagliptin interMediate A
  • 3-(Trifluoromethyl)-5,6,7,8-tetra-hydro-[1,2,4]-Triazolo-[4,3-a]-pyrazine hydrochloride Salt
  • 5,6,7,8-Tetrahydro-3-(trifluormethyl)-[4,3-a]-1,2,4-triazolopyrazine hydrochloride
  • 3-(Trifluoromethyl)-5
  • 3-(trifluoromethyl)-5,6,7,8-tetrahydro
  • 3-(Trifluoromethyl)-5 6 7 8-tetrahydro-1 2 4triazolo4 3-apyrazine hydroch
  • Sitagliptin hydrochloride
  • 3-(Trifluoromethyl)-5,6,7,8-Tetrahydro-[1,2,4]Triazolo[4,3-A]Pyrazine Hydrochloride / Sitagliptin Intermediate
  • SitagliptinImpurity20-d4
  • 4-(Trifluoromethyl)-5,6,7,8-tetrahydro [1,2,4] Triazolo[4,3-a]pyrazine Hydrochloride
  • 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride,[1,2,4]Triazolo[4,3-a]Pyrazine Hydrochloride 762240-92-6 Sitagliptin
  • 3-(Trifluoromethyl)-5,6,7,8-tetrahydro- triazolopyrazine Hydrochloride (Triazole)
  • 3-(TRIFLUOROMETHYL)-5,6,7,8-TETRAHYDRO-[1,2,4]TRIZOLO[4,3-A]PYRAZINE HYDROCHLORIDE
  • 3- (Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2.41 triazolo[4,3-a] pyrazine hydrochloride,TRIAZOLE
  • 3-(trifluoromethyl)-5,6,7, 8-tetrahydro-[1,2,4] triazole and [4,3-a] pyrazine hydrochloride
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