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ACONINE

ACONINE Struktur
509-20-6
CAS-Nr.
509-20-6
Englisch Name:
ACONINE
Synonyma:
ACONINE;Aconitysat;Jesaconine;ACONINE USP/EP/BP;Aconine (Jesaconine);20-ethyl-1,6,16-trimethoxy-4-(methoxymethyl)aconitane-3,8,13...;20-Ethyl-1α,6α,16β-trimethoxy-4-(methoxymethyl)aconitane-3α,8,13,14α,15α-pentol;(15S,16S)-20-Ethyl-1α,6α,16-trimethoxy-4-(methoxymethyl)aconitane-3α,8β,13β,14α,15-pentol;Aconitane-3,8,13,14,15-pentol,20-ethyl-1,6,16-trimethoxy-4-(methoxymethyl)-, (1a,3a,6a,14a,15a,16b)-;Aconitane-3,8,13,14,15-pentol, 20-ethyl-1,6,16-trimethoxy-4-(methoxymethyl)-, (1α,3α,6α,14α,15α,16β)-
CBNumber:
CB31229467
Summenformel:
C25H41NO9
Molgewicht:
499.6
MOL-Datei:
509-20-6.mol
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ACONINE Eigenschaften

Schmelzpunkt:
129-131℃
alpha 
D +23°
Siedepunkt:
590.79°C (rough estimate)
Dichte
1.42
Brechungsindex
1.6000 (estimate)
storage temp. 
-20°C Freezer
Löslichkeit
Chloroform (Slightly), DMSO (Slightly)
pka
9.52(at 25℃)
Aggregatzustand
Solid
Farbe
Off-White to Pale Yellow

Sicherheit

ACONINE Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Aconine is an alkaloid originally isolated from Aconitum species and active metabolite of aconitine. It inhibits osteoclast differentiation of RANKL-stimulated RAW 264.7 cells and bone resorption in a pit formation assay in a concentration-dependent manner. Aconine also inhibits RANKL-induced activation of NF-κB and NFATc1 in RAW 264.7 cells. In vivo, aconine is toxic to mice when administered intravenously at a dose of 120 mg/kg. It induces flaccid paralysis and toxicity in rats with toxic dose (TD50) and LD50 values of 1.5 and 1.7 μmol per animal, respectively.

ACONINE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

ACONINE Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 117)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Shaanxi Haibo Biotechnology Co., Ltd 		+undefined18602966907
 qinhe02@xaltbio.com China 1000 58
Hangzhou FandaChem Co.,Ltd. 		008657128800458; +8615858145714
 fandachem@gmail.com China 9348 55
career henan chemical co 		+86-0371-86658258
sales@coreychem.com China 29914 58
Chengdu GLP biotechnology Co Ltd 		028-87075086 13350802083
 scglp@glp-china.com CHINA 1824 58
Chengdu Biopurify Phytochemicals Ltd. 		+8618080483897
 sales@biopurify.com China 3424 58
Hubei Jusheng Technology Co.,Ltd. 		18871490254
linda@hubeijusheng.com CHINA 28180 58
BOC Sciences 		+1-631-485-4226
inquiry@bocsci.com United States 19553 58
Chongqing Chemdad Co., Ltd 		+86-023-61398051 +8613650506873
 sales@chemdad.com China 39916 58
Neostar United (Changzhou) Industrial Co., Ltd. 		+86-519-519-85557386
marketing1@neostarunited.com China 8349 58
Wuhan ChemNorm Biotech Co.,Ltd. 		+86-27-8439 4403 18971486879
 sales@chemnorm.com CHINA 2935 58

509-20-6()Verwandte Suche:

Aconitin
  • ACONINE
  • (15S,16S)-20-Ethyl-1α,6α,16-trimethoxy-4-(methoxymethyl)aconitane-3α,8β,13β,14α,15-pentol
  • 20-Ethyl-1α,6α,16β-trimethoxy-4-(methoxymethyl)aconitane-3α,8,13,14α,15α-pentol
  • (1alpha,3alpha,6alpha,14alpha,15alpha,16beta)-20-Ethyl-1,6,16-trimethoxy-4-(methoxymethyl)aconitane-3,8,13,14,15-pentol
  • Jesaconine
  • Aconitane-3,8,13,14,15-pentol,20-ethyl-1,6,16-trimethoxy-4-(methoxymethyl)-, (1a,3a,6a,14a,15a,16b)-
  • Aconine (Jesaconine)
  • Aconitane-3,8,13,14,15-pentol, 20-ethyl-1,6,16-trimethoxy-4-(methoxymethyl)-, (1α,3α,6α,14α,15α,16β)-
  • ACONINE USP/EP/BP
  • 20-ethyl-1,6,16-trimethoxy-4-(methoxymethyl)aconitane-3,8,13...
  • Aconitysat
  • 509-20-6
  • C25H41NO9
  • Alkaloids
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
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