PD 117519 Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
N6-Substituted adenosine receptor agonist; a potential antihypertensive agent.
in vitro
PD 117519 (2-10 mg/kg; oral administration; 16-24 hours; male beagle dogs) treatment produces significant hemodynamic changes at Tmax (4 hours) follows by acute coronary vascular injury that is evident at 16 hours postdosing.Treatment with 2 or 10 mg/kg of PD 117519 produces significant increases in mean heart rate and decreases in mean indirectsystolic blood pressure at time of highest drug exposure, 4 hours postdosing.
PD 117519 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
