Sevelamer carbonate
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- CAS-Nr.
- 845273-93-0
- Englisch Name:
- Sevelamer carbonate
- Synonyma:
- Sevelam;Sevelam carbonate;Sevelamer carbonate;2-Propen-1-aminepolymerwith;Sevelamer Carbonate, Technical Grade;SIM862 Sevelamer Carbonate-----25gm;2-Propen-1-amine polymer with (chloromethyl)oxiran;carbonic acid,2-(chloromethyl)oxirane,prop-2-en-1-amine;2-Propen-1-amine polymer with (chloromethyl)oxirane carbonate;Carbonic acid, compd. with 2-(chloromethyl)oxirane polymer with 2-propen-1-amine
- CBNumber:
- CB32128754
- Summenformel:
- C7H14ClNO4
- Molgewicht:
- 211.64
- MOL-Datei:
- 845273-93-0.mol
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Sevelamer carbonate Eigenschaften
- storage temp.
- Room Temperature, under inert atmosphere
- Löslichkeit
- <4.74mg/mL in DMSO
- Aggregatzustand
- Solid
- Farbe
- White to Pale Beige
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H412 |
Schädlich für Wasserorganismen, mit langfristiger Wirkung. |
Langfristig (chronisch) gewässergefährdend |
Kategorie 3 |
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P273, P501 |
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| Sicherheit |
| P273 |
Freisetzung in die Umwelt vermeiden. |
| P501 |
Inhalt/Behälter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
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Sevelamer carbonate Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Sevelamer carbonate (SC) is a non-absorbed phosphate binding crosslinked polymer, with the same polymeric structure as sevelamer hydrochloride, in which carbonate replaces chloride as the counterion. SC has been found to have the same safety and efficacy profile as Sevelamer HCl in HD patients.
Sevelamer carbonate(Renvela) is a nonaluminum, non-calcium-basedphosphorus binder that traps phosphorus in the bowel through ion exchange and hydrogen binding. This drug replaced sevelamer hydrochloride(Renagel) and has an advantage of not generating an acid load, as its precursor, sevelamer hydrochloride, did. It also has the advantage of lowering LDL cholesterol due to gut binding of bile acids.
Verwenden
Sevelamer Carbonate, a non-?absorbed polymer is an oral phosphate binder in patients with kidney failure. It is reported that Sevelamer Carbonate is less likely to cause hypercalcemia, low levels of PTH, and progressive coronary and aortic calcification in hemodialysis patients than calcium-?based phosphate binders.
Sevelamer carbonate Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Sevelamer carbonate Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 199)Lieferanten
845273-93-0()Verwandte Suche:
- 2-Propen-1-amine polymer with (chloromethyl)oxirane carbonate
- Sevelamer carbonate
- Carbonic acid, compd. with 2-(chloromethyl)oxirane polymer with 2-propen-1-amine
- Sevelam
- 2-Propen-1-amine polymer with (chloromethyl)oxiran
- 2-Propen-1-aminepolymerwith
- carbonic acid,2-(chloromethyl)oxirane,prop-2-en-1-amine
- SIM862 Sevelamer Carbonate-----25gm
- Sevelamer Carbonate, Technical Grade
- 2-Propen-1-amine polymer with (chloromethyl)oxirane carbonate ISO 9001：2015 REACH
- Sevelam carbonate
- 845273-93-0
- C3H7NmC3H5ClOnCH2O3x
- C3H7NC3H5ClOxxCH2O3
- Inhibitors
- Pharmaceutical intermediate
- Other APIs
