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Allantoin Produkt Beschreibung

Allantoin Struktur
97-59-6
CAS-Nr.
97-59-6
Bezeichnung:
Allantoin
Englisch Name:
Allantoin
Synonyma:
ALL;toin;nsc7606;Sebical;Alantan;Allantin;Alphosyl;Allantoi;Psoralon;Septalan
CBNumber:
CB3215461
Summenformel:
C4H6N4O3
Molgewicht:
158.12
MOL-Datei:
97-59-6.mol

Allantoin Eigenschaften

Schmelzpunkt:
230 °C (dec.) (lit.)
Siedepunkt:
283.17°C (rough estimate)
Dichte
1.6031 (rough estimate)
Brechungsindex
1.8500 (estimate)
Flammpunkt:
230-234°C
storage temp. 
2-8°C
Löslichkeit
H2O: soluble0.1g/10 mL, clear, colorless
Aggregatzustand
Powder
pka
8.96(at 25℃)
Farbe
White
Wasserlöslichkeit
Slightly soluble in water. Freely soluble in alkalis
Decomposition 
230-234 ºC
Merck 
14,258
BRN 
102364
Stabilität:
Stable. Incompatible with strong oxidizing agents.
InChIKey
POJWUDADGALRAB-UHFFFAOYSA-N
CAS Datenbank
97-59-6(CAS DataBase Reference)
NIST chemische Informationen
Urea, (2,5-dioxo-4-imidazolidinyl)-(97-59-6)
EPA chemische Informationen
Allantoin (97-59-6)
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
Kennzeichnung gefährlicher Xn,Xi
R-Sätze: 22-36/37/38
S-Sätze: 22-24/25-36-26
WGK Germany  1
RTECS-Nr. YT1600000
TSCA  Yes
HS Code  29332100
Giftige Stoffe Daten 97-59-6(Hazardous Substances Data)
Bildanzeige (GHS)
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitsschädlich bei Verschlucken. Akute Toxizität oral Kategorie 4 Warnung P264, P270, P301+P312, P330, P501
Sicherheit

Allantoin Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:

R22:Gesundheitsschädlich beim Verschlucken.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.

S-Sätze Betriebsanweisung:

S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.

Beschreibung

Allantoin is a product of purine and uric acid metabolism. It is formed through oxidation of uric acid by urate oxidase in most mammals but is formed only through non-enzymatic oxidation by free radicals in humans. Urinary levels of allantoin are increased prior to the onset of Alzheimer’s disease symptoms in mice expressing mutations in amyloid precursor protein and tau (APP/tau) but not during the early/middle stage of the disease, indicating its potential use as a biomarker for predicting Alzheimer’s disease onset. Due to the formation of allantoin by free radicals in humans, increased urinary levels are a potential biomarker for oxidative stress status.

Chemische Eigenschaften

White Solid

Originator

Allantoin ,Arocor Holdings Inc.

Verwenden

wound healing agent

Verwenden

diuretic

Verwenden

Vulnerary; debriding agent. Purine metabolite via the uric acid pathway.

Verwenden

allantoin is a botanical extract said to be healing, calming, and soothing, it can also help protect the skin from harmful external factors (e.g., wind burn). It is considered an excellent temporary anti-irritant and is believed to stimulate new tissue growth, helping heal damaged skin. Allantoin is appropriate for sensitive, irritated, and acne skins. Derived from the comfrey root, it is considered non-allergenic.

Definition

ChEBI: An imidazolidine-2,4-dione that is 5-aminohydantoin in which a carbamoyl group is attached to the exocyclic nitrogen.

Manufacturing Process

To a mixture of 13.14 kg 40% solution of glyoxal in water and a solution of 0.5 L of concentrated HCl in 3 L of water was added 1.8 g Co(NO3)2·6H2O. The mixture was heated at 50-60°C, to the solution was added 20 g of sodium nitrite and then at 40-60°C was added dropwise the mixture of 6 L of concentrated HNO3, 4.2 L of water and 30 g of sodium nitrite. The product obtained was mixed with 2.4 kg ammonium sulfate and filtrated. The filtrate was heated with 14.5 kg urea at 70°C for 10 hours. Allantoin was filtrated and recrystallized from the water; M.P. 233-235°C.

Therapeutic Function

Vulnerary, Antiulcer (topical), Antipsoriatic

Allgemeine Beschreibung

Allantoin, the final catabolic product of purines in mammals, is a highly polar and amphoteric substance. Allantoin is mainly used for skin protection as the drug promotes cell proliferation and wound healing.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Biochem/physiol Actions

Purine metabolite via the uric acid pathway. Uric acid also reacts with free radicals to produce allantoin, thus allantoin may be a useful biomarker for oxidative stress.

läuterung methode

It crystallises from water or EtOH [Hartman et al. Org Synth Coll Vol II 21 1943]. [Beilstein 25 III/IV 4071.]

Allantoin Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Allantoin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 611)Lieferanten
Firmenname Telefon Fax E-Mail Land Produktkatalog Edge Rate
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418679
86-0551-65418697 info@tnjchem.com China 3000 55
Connect Chemicals GmbH
+49 2102 2077-39
+49 2102 2077-40 inquiries@connectchemicals.com Germany 265 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com China 22607 55
Hangzhou FandaChem Co.,Ltd.
008615858145714
+86-571-56059825 fandachem@gmail.com CHINA 9134 55
Nanjing Finetech Chemical Co., Ltd.
025-85710122 17714198479
025-85710122 sales@fine-chemtech.com CHINA 890 55
Tianjin Zhongxin Chemtech Co., Ltd.
+8618622897568 +86-022-66880623
022-66880086 sales@tjzxchem.com China 543 58
Shanxi Naipu Import and Export Co.,Ltd
+8613734021967
kaia@neputrading.com CHINA 1011 58
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3623 58
career henan chemical co
+86-0371-55982848
sales@coreychem.com China 29954 58
Shaanxi Yikanglong Biotechnology Co., Ltd.
17791478691
yklbiotech@163.com CHINA 297 58

97-59-6(Allantoin)Verwandte Suche:


  • (2,5-dioxo-4-imidazolidinyl)urea
  • ALLANTOIN
  • ALL
  • 5-UREIDOHYDANTOIN
  • Alphosyl
  • Alyonyldiurened
  • Egopsoryl
  • Allantin
  • CORDIANINE
  • Allantoin,98%
  • 1-(2,5-Dioxoimidazolidin-4-yl)-urea
  • Allantoin (200 mg)
  • Allantoin, USP, EP
  • 5-Ureidohydantoin, Glyoxylic(acid) diureide
  • [(4R)-2,5-dioxoiMidazolidin-4-yl]urea
  • Allantoin, 98% 100GR
  • Allantoin skin curative
  • Allantoi
  • glyoxylic diureide
  • GLYOXYLIDIUREIDE
  • GLYOXYLIC ACID DIUREIDE
  • glyoxyldiureid
  • GLYOXYLDIUREIDE
  • LABOTEST-BB LT02085084
  • TIMTEC-BB SBB003997
  • UREA, (2,5-DIOXO-4-IMIDAZOLIDINYL)
  • Hydantoin, 5-ureido-
  • N-(2,5-Dioxo-4-imidazolidinyl)urea
  • nsc7606
  • Psoralon
  • Sebical
  • Septalan
  • toin
  • uniderma
  • (2,5-Dioxo-imidazolidin-4-yl)-urea
  • AllantoinPowder
  • ALLANTOIN POWDER ( Glyoxylic acid Diureide)
  • Allantoin Joyce
  • Allantoin >=98.0% (N)
  • AllantoinuM
  • Alantan、Allegron、Alphosyl、Alyonyldiurened、Cordianine、Egopsoryl、Sebical
  • Urea, N-(2,5-dioxo-4-imidazolidinyl)-
  • AllantoinUSP, 98.5-101.0% (Assay)
  • (2,5-Dioxo-4-imidazolidinyl)urea 5-Ureidohydantoin Glyoxyldiureide Cordianine
  • ALLANTOIN (5-UREIDOHYDANTOIN)
  • Allantoine ( 2,5-Dioxo-4-imidazoidinyl urea)
  • 5-ureido-hydantoi
  • 5-Ureidohydrantoin
  • ai3-15281
  • Alantan
  • Allantol
  • AVC/Dienestrolcream
  • component of Skin-balm
  • Fancol TOIN
  • 5-ureidohydantoin (2,5-dioxoimidazolidin-4-yl)urea
  • ALLANTOIN(RG)
  • 2,5-DIOXO-4-IMIDAZOLIDINYLUREA(ALLANTOIN)
  • ALANTOIN
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