Butan-1-thiol Chemische Eigenschaften,Einsatz,Produktion Methoden
ERSCHEINUNGSBILD
FARBLOSE BIS GELBE FLüSSIGKEIT MIT CHARAKTERISTISCHEM GERUCH.
PHYSIKALISCHE GEFAHREN
Die Dämpfe sind schwerer als Luft und können sich am Boden ausbreiten. Fernzündung möglich.
CHEMISCHE GEFAHREN
Zersetzung beim Erhitzen unter Bildung giftiger Rauche (Schwefeloxide- s. ICSC 0074). Reagiert mit Säuren, Basenund starken Oxidationsmitteln.
ARBEITSPLATZGRENZWERTE
TLV: 0,5 ppm (als TWA) (ACGIH 2005).
MAK: 0,5 ppm 1,9 mg/m? Spitzenbegrenzung: überschreitungsfaktor II(2); Schwangerschaft: Gruppe C; (DFG 2005).
AUFNAHMEWEGE
Aufnahme in den Körper durch Inhalation.
INHALATIONSGEFAHREN
Beim Verdampfen bei 20 °C kann sehr schnell eine gesundheitsschädliche Kontamination der Luft eintreten.
WIRKUNGEN BEI KURZZEITEXPOSITION
WIRKUNGEN BEI KURZZEITEXPOSITION: Die Substanz reizt die Augen, die Haut und die Atmungsorgane. Möglich sind Auswirkungen auf die Schilddrüse. Exposition weit über den Arbeitsplatzgrenzwerten kann Auswirkungen auf das Nervensystem haben und kann Bewusstseinstrübung verursachen.
LECKAGE
Gefahrenbereich verlassen! Zündquellen entfernen. Ausgelaufene Flüssigkeit möglichst in abdichtbaren Behältern sammeln. Reste mit Sand oder inertem Absorptionsmittel aufnehmen und an einen sicheren Ort bringen. NICHT in die Kanalisation spülen! NICHT in die Umwelt gelangen lassen. Chemikalienschutzanzug mit umgebungsluftunabhängigem Atemschutzgerät.
R-Sätze Betriebsanweisung:
R11:Leichtentzündlich.
R20/22:Gesundheitsschädlich beim Einatmen und Verschlucken.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
R21/22:Gesundheitsschädlich bei Berührung mit der Haut und beim Verschlucken.
S-Sätze Betriebsanweisung:
S16:Von Zündquellen fernhalten - Nicht rauchen.
S23:Gas/Rauch/Dampf/Aerosol nicht einatmen(geeignete Bezeichnung(en) vom Hersteller anzugeben).
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S9:Behälter an einem gut gelüfteten Ort aufbewahren.
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
S33:Maßnahmen gegen elektrostatische Aufladungen treffen.
Beschreibung
Butane thiol, also known as butyl mercaptan, is a volatile, clear to yellowish liquid with a fetid (extremely foul-smelling) odor, commonly described as "skunk" odor. In fact, butanethiol is structurally similar to several major constituents of a skunk's defensive spray but is not actually present in the spray. The scent of butanethiol is so strong that the human nose can easily detect it in the air at concentrations as low as 10 parts per billion. The threshold level for 1-butane thiol is reported as 1.4 ppb.
Chemische Eigenschaften
Butanethiol is also known as butyl mercaptan. It is a volatile, highly flammable clear to
yellowish liquid with an extremely foul-smelling, strong, garlic-, cabbageor skunk-like Butanethiol is also known as butyl mercaptan. It is a volatile, highly flammable clear to
yellowish liquid with an extremely foul-smelling, strong, garlic-, cabbageor skunk-like
Physikalische Eigenschaften
Clear, colorless liquid with a strong garlic, cabbage, or pungent skunk-like odor. Odor threshold
concentrations of 0.0028 ppb
v and 3.7 μg/m
3 (1.0 ppb
v) were reported by Katz and Talbert (1930)
and Nagata and Takeuchi (1990), respectively.
Occurrence
Reported found in beef, cheddar cheese, raw chicken, cooked potatoes, beer and boiled eggs.
Verwenden
Butanethiol is used as an industrial solvent , and as an intermediate for cotton defoliants. It is some times placed in the "stink bombs" and "stink perfumes" for prankster.
Allgemeine Beschreibung
Butanethiol is also known as butyl mercaptan. It is a volatile, clear to yellowish liquid with an extremely foul smell, with a strong, garlic-, cabbage-, or skunk-like odour. It is slightly oily in nature. Butanethiol is used as a chemical intermediate in the production of insecticides and herbicides. It is also used as a gas odorant.
Air & Water Reaktionen
Highly flammable. Slightly soluble in water.
Reaktivität anzeigen
Butanethiol is incompatible with acids, diazo and azo compounds, halocarbons, isocyanates, aldehydes, alkali metals, nitrides, hydrides, and other strong reducing agents. Reactions with these materials generate heat and in many cases hydrogen gas. May liberate hydrogen sulfide upon decomposition or reaction with an acid. Incompatible with strong oxidizing agents [USCG, 1999].
Hazard
Toxic by inhalation. Flammable, dangerous
fire risk. Upper respiratory tract irritant.
Health Hazard
Exposures to butanethiol cause adverse health effects and poisoning. The symptoms of
poisoning in exposed workers include, but are not limited to, asthenia, muscular weak ness, malaise, sweating, nausea, vomiting, headache, restlessness, increased respiration,
incoordination, muscular weakness, skeletal muscle paralysis in most cases, heavy to mild
cyanosis, lethargy and/or sedation, respiratory depression followed by coma. Severe cases
of poisoning lead to death of the exposed worker.
In laboratory studies, animals given intraperitoneal and oral exposures of butane thiol survived near-lethal single doses. However, after 20 days post-treatment, animals
showed pathological changes involving liver and kidney damage. The pathomorpho logical changes in the liver included cloudy swelling, fatty degeneration, and necrosis.
Pathological changes in the kidneys included cloudy swelling, and the lungs displayed
capillary engorgement, patchy edema, and occasional hemorrhage
Chemische Reaktivität
Reactivity with Water No reaction; Reactivity with Common Materials: No reactions; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Not pertinent; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent.
Sicherheitsprofil
Poison by
intraperitoneal route. Moderately toxic by
ingestion. An eye irritant. Dangerous fire
hazard by exposure to heat, flame, sparks, or
powerful oxidizers. Reacts violently with
HNO3. Incompatible with acids, acid fumes,
oxidizing materials, heat, flame, and sparks.
To fight fire, use alcohol foam. When
heated to decomposition it emits toxic SOx.
See also MERCAPTANS.
Sicherheit(Safety)
Butanethiol is a very noxious and caustic chemical compound, and at sufficiently high concentrations, it produces serious health effects in both humans and animals, especially as a result of prolonged exposure. Higher concentrations can lead to unconsciousness and coma after prolonged exposure. Contact with the skin and mucous membranes causes burns, and contact with the eyes can lead to blurred vision or complete blindness.
Inhalation may cause weakness, confusion, cough, dizziness, drowsiness, headache, nausea, vomiting, and shortness of breath. The substance irritates the eyes, the skin, and the respiratory tract. It may cause effects on the thyroid and the nervous system and could cause lowering of consciousness.
mögliche Exposition
Butyl mercaptan is a flammable, colorless liquid with a strong, skunk-like odor. The Odor Threshold in
air is 0.00097 ppm. Molecular weight 5 90.19; Specific
gravity (H2O:1) 5 0.83 @ 20C; boiling point 5 99C;freezing/melting point 5 2116C; vapor
pressure 5 35 mmHg @ 20C; 75 mmHg @ 34.5C; relative vapor density (air 5 1) 5 3.1; Flash point 5 2C
(cc); Autoignition temperature # 225C. Explosive limits: LEL: 1.4%; UEL: 10.2%. Hazard identification (based
on NFPA-704 M Rating System): Health 1; flammability 3;
reactivity 0 ?. Slightly soluble in water; solubility 5 0.06%
@ 20C.
Environmental Fate
Chemical/Physical. Releases toxic sulfur oxide fumes when heated to decomposition (Sax and
Lewis, 1987).
Versand/Shipping
UN2347 Butyl mercaptan, Hazard Class: 3;
Labels: 3—Flammable liquid
läuterung methode
Dry the thiol with CaSO4 or Na2SO4, then reflux it over magnesium, or dry with, and distil it from CaO, under nitrogen [Roberts & Friend J Am Chem Soc 108 7204 1986.] It has been separated from hydrocarbons by extractive distillation with aniline. Dissolve it also in 20% NaOH, extract with a small amount of *C6H6, then steam distil it until clear. The solution is then cooled and acidified slightly with 15% H2SO4. The thiol is distilled out, dried with CaSO4 or CaCl2, and fractionally distilled under N2 [Mathias & Filho J Phys Chem 62 1427 1958]. It has also been purified by precipitation as the lead mercaptide from alcoholic solution, then regeneration by adding dilute HCl to the residue followed by steam distillation. All operations should be carried out in a fume cupboard due to the TOXICITY and obnoxious odour of the thiol. [Beilstein 1 IV 1555.]
Inkompatibilitäten
May form explosive mixture with air.
Incompatible with oxidizers (chlorates, nitrates, peroxides,
permanganates, perchlorates, chlorine, bromine, fluorine,
etc.); contact may cause fires or explosions. Keep away
from alkaline materials, strong bases, strong acids, oxoacids, epoxides. Attacks some plastics and rubber
Waste disposal
Incineration (1093C) followed by scrubbing with a caustic solution.
Vorsichtsmaßnahmen
Butanethiol decomposes an heading and release toxic fumes. It reacts with strong acids,
bases and strong oxidants. Workers during handling of butanethiol should be very careful,
should avoid open flames, sparkings, and smoking. Chemical vapor/air mixtures cause
explosion ha3 and workers should wear protective cloathing, safety goggles and breathing
apparatus and should work in good ventillation
Butan-1-thiol Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
