C-Peptide EIA Kit
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- CAS-Nr.
- Englisch Name:
- C-Peptide EIA Kit
- Synonyma:
- C-Peptide EIA Kit
- CBNumber:
- CB32892019
- Summenformel:
- Molgewicht:
- 0
- MOL-Datei:
- Mol file
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C-Peptide EIA Kit Eigenschaften
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H290 |
Kann gegenüber Metallen korrosiv sein. |
Korrosiv gegenüber Metallen |
Kategorie 1 |
Warnung |
![GHS hazard pictograms]() src="/GHS05.jpg" width="20" height="20" /> |
P234, P390, P404 |
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| Sicherheit |
| P234 |
Nur im Originalbehälter aufbewahren. |
| P390 |
Verschüttete Mengen aufnehmen, um Materialschäden zu vermeiden. |
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C-Peptide EIA Kit Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT
Procedure (sandwich, competitive & Indirect ELISA)
Allgemeine Beschreibung
The C-Peptide Enzyme Immunoassay (EIA) Kit is an in vitro quantitative assay for detecting C-Peptide peptide based on the principle of Competitive Enzyme Immunoassay. EIA-CPE-1 only detects C-peptide, not Insulin A or B chain.
Biochem/physiol Actions
C-peptide inhibits endothelial dysfunction under high glucose conditions via inhibition of nuclear factor-κB (NF-κB) pathway. Experimental studies suggest that prolonged dosage of physiological concentration of C-peptide to type 1 diabetes patients minimizes diabetes-induced complications, such as glomerular hypertrophy and mesangial matrix expansion by interrupting transforming growth factor β1 (TGF-β1) and tumor necrosis factor α (TNFα) signaling pathway. C-peptide reduces diabetes-induced glomerular hyperfiltration by contraction of the afferent arteriole, dilation of the efferent arteriole, and by inhibition of tubular reabsorption. C-Peptide also plays a crucial role in renal pathophysiology. C-peptide binds to a cell surface receptor that is likely to be G-protein coupled. This interaction stimulates various cellular functions such as increasing intracellular Ca2+ concentration, enhancing PI3-K (phosphoinositide 3-kinase) activity, increased endothelial nitric oxide synthase (eNOS) transcription, and activation of the Na+/K+ ATPase and mitogen-activated protein kinase (MAPK) signaling pathway.
C-Peptide EIA Kit Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
C-Peptide EIA Kit Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 2)Lieferanten
