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Vecuroniumbromid Produkt Beschreibung

Vecuronium bromide Struktur
50700-72-6
CAS-Nr.
50700-72-6
Bezeichnung:
Vecuroniumbromid
Englisch Name:
Vecuronium bromide
Synonyma:
VBMC;nc-45;orgnc45;norcuron;Musculax;Muscurate;vecuronium;mide,diacetate;VECRONIUM BROMIDE;Vecuronim Bromide
CBNumber:
CB3382859
Summenformel:
C34H57BrN2O4
Molgewicht:
637.73138
MOL-Datei:
50700-72-6.mol

Vecuroniumbromid Eigenschaften

Schmelzpunkt:
227-229°C
alpha 
+30.5~+35.0゜(D/20℃)(c=0.5,dil.HCl)
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
Löslichkeit
Slightly soluble in water, freely soluble in methylene chloride, sparingly soluble in acetonitrile and in anhydrous ethanol.
Aggregatzustand
neat
Merck 
14,9941
BRN 
4837308
InChIKey
VEPSYABRBFXYIB-PWXDFCLTSA-M
CAS Datenbank
50700-72-6(CAS DataBase Reference)
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
Kennzeichnung gefährlicher Xi,Xn
R-Sätze: 36/37/38-22
S-Sätze: 26-37/39
WGK Germany  3
RTECS-Nr. TN4875000
HS Code  2933399090
Toxizität LD50 in mice: 0.061 mg/kg i.v. (Buckett)
Bildanzeige (GHS)
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitsschädlich bei Verschlucken. Akute Toxizität oral Kategorie 4 Warnung P264, P270, P301+P312, P330, P501
Sicherheit

Vecuroniumbromid Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:

R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.

S-Sätze Betriebsanweisung:

S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.

Beschreibung

Vecuronium, 1-[(2β,3α,5α,16β,17β,)-3,17-bis(acetyloxy)-2-(1-piperidinyl) androstan-16-yl]-1-methylpiperidinium bromide (15.1.9), differs from panuronium only in the extent of alkylation. Only the piperidine substituent on C16 of the steroid skeleton is transformed into a quaternary salt.

Chemische Eigenschaften

White Solid

Verwenden

alcohol antagonist

Verwenden

An aminosteroid, competitive neuromuscular blocker agent.

Definition

ChEBI: The organic bromide salt of a 5alpha-androstane compound having 3alpha-acetoxy-, 17beta-acetoxy-, 2beta-piperidinino- and 16beta-N-methylpiperidinium su stituents.

Trademarks

Norcuron (Organon).

Biologische Funktion

Vecuronium bromide (Norcuron) is chemically identical to pancuronium except for a tertiary amine in place of a quaternary nitrogen. However, some of the drug will exist as the bisquaternary compound, depending on body pH. Vecuronium has a moderate onset of action (2.4 minutes) and a duration of effect of about 50 minutes. Like pancuronium, it does not block ganglia or vagal neuroeffector junctions, does not release histamine, and is eliminated by urinary excretion.

Allgemeine Beschreibung

Vecuronium bromide, 1-(3 ,17 -dihydroxy-2 -piperidino-5 -androstan-16 -yl)-1-methylpiperidinium bromide diacetate (Norcuron), is themonoquaternary analog of pancuronium bromide. It belongsto the class of nondepolarizing neuromuscular blockingagents and produces effects similar to those of drugs in thisclass. It is unstable in the presence of acids and undergoesgradual hydrolysis of its ester functions in aqueous solution.Aqueous solutions have a pH of about 4.0.

Clinical Use

Vecuronium Bromide is usedmainly to produce skeletal muscle relaxation during surgeryand to assist in controlled respiration after general anesthesiahas been induced.

Veterinary Drugs and Treatments

Vecuronium is indicated as an adjunct to general anesthesia to produce muscle relaxation during surgical procedures or mechanical ventilation and to facilitate endotracheal intubation. It causes very minimal cardiac effects and generally does not cause the release of histamine.

Vecuroniumbromid Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Vecuroniumbromid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 330)Lieferanten
Firmenname Telefon Fax E-Mail Land Produktkatalog Edge Rate
Henan DaKen Chemical CO.,LTD.
+86-371-66670886
info@dakenchem.com China 20914 58
Beijing Cooperate Pharmaceutical Co.,Ltd
010-60279497
010-60279497 sales01@cooperate-pharm.com CHINA 1817 55
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 22607 55
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 29954 58
Hebei Guanlang Biotechnology Co., Ltd.
+8619930503282
sales3@crovellbio.com China 5892 58
Xiamen AmoyChem Co., Ltd
+86 592-605 1114
sales@amoychem.com CHINA 6369 58
Shandong chuangyingchemical Co., Ltd.
18853181302
sale@chuangyingchem.com CHINA 5917 58
Beijing Yibai Biotechnology Co., Ltd
0086-182-6772-3597
sales04@yibaibiotech.com CHINA 420 58
Chongqing Chemdad Co., Ltd
+86-13650506873
sales@chemdad.com CHINA 37282 58
Shanghai Yingrui Biopharma Co.,Ltd
+86-21-33585366
+86-21-34979012 export01@shyrchem.com CHINA 1321 58

50700-72-6(Vecuroniumbromid)Verwandte Suche:


  • norcuron
  • [(2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-17-acetoxy-10,13-dimethyl-16-(1-methylpiperidin-1-ium-1-yl)-2-(1-piperidyl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate
  • 1-[(2Beta,3alpha,5alpha,16beta,17beta)-3,17-bis(acetyloxy)-2-(1-piperidinyl)androstan-16-yl]-1-methylpiperidinium bromide hydrate
  • 1-(3-alpha,17-beta-diacetoxy-2-beta-piperidino-5-alpha-androstan-piperidiniu
  • 17beta-diol,16beta-pipecolinio-2beta-piperidino-5alpha-androstan-3alphbro
  • mide,diacetate
  • nc-45
  • orgnc45
  • vecuronium
  • 1-(3alpha,17beta-Dihydroxy-2beta-piperidino-5alpha-androstan-16beta,5alpha-yl)-1-methylpiperidinium bromide, diacetate
  • Muscurate
  • VercuoniuM BroMide
  • VecuroniuM broMide(Norcuron)
  • 1-[5,14-bis(acetyloxy)-2,15-diMethyl-4-(piperidin-1-yl)tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan-13-yl]-1-Methylpiperidin-1-iuM broMide
  • VecuroniuM BroMide Hydrate
  • Piperidinium, 1-[(2β,3α,5α,16β,17β)-3,17-bis(acetyloxy)-2-(1-piperidinyl)androstan-16-yl]-1-methyl-, bromide (1:1)
  • 1-[(2β,3α,5α,16β,17β)-3,17-Bis(acetyloxy)-2-(1-piperidinyl)androstan-16-yl]-1-methyl-piperidinium bromide
  • (Vecuroniun bromide)
  • Vecuronium bromide, >=99%
  • (+)-1-(3,17-diacetoxy-2-piperidino-5-androstan-16-yl)-1-methylpiperidinium bromide
  • VECURONIUM BROMIDE, USP STANDARD
  • VECURONIUM BROMIDE, RELATED COMPOUND A3ALPHA, 17BETA-DIACETYL-OXY-2BETA, 16BETA-BISPIPERIDINYL-5ALPHA-ANDROSTAN USP STANDARD
  • VECURONIUM BROMIDE, EP
  • VECUROMIUM BROMIDE
  • VECURUNIUM BROMIDE
  • Musculax
  • Piperidinium, 1-[(2b,3a,5a,16b,17b)-3,17-bis(acetyloxy)-2-(1-piperidinyl)androstan-16-yl]-1-methyl-, bromide (9CI)
  • VECURONIUM BROMIDE
  • VECRONIUM BROMIDE
  • Piperidinium, 1-[(2,3α,5α ,16,17)-3,17-bis(acetyloxy)-2-(1-piperidinyl )androstan-16-yl]-1-methyl-, bromide
  • 1-[(2, β,3α,5α,16β,17β)-3,17-Bis(acetoxy)-2-(1-piperidinyl)androstan-16-yl]-1-methylpiperidinium bromide
  • VBMC
  • 1-(3,17-Diacetoxy-2-piperidino-5-androstan-16-yl)-
  • VENCURONIUM BROMIDE
  • 5alpha-Androstan-3alpha,17beta-diol,-16beta-pipecolinio-2beta-piperidino-,bromide,diacetate
  • Piperidinium, 1-(3-alpha,17-beta-diacetoxy-2-beta-piperidino-5-alpha-androstan-16-beta-yl)- 1-methyl-, bromide
  • Vecuronium bromide CRS
  • 1-((2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-3,17-diacetoxy-10,13-dimethyl-2-(piperidin-1-yl)hexadecahydro-1H-cyclopenta[a]phenanthren-16-yl)-1-methylpiperidin-1-ium bromide
  • 1-((2S,3S,5S,10S,13S,16S,17R)-3,17-Diacetoxy-10,13-dimethyl-2-(piperidin-1-yl)hexadecahydro-1H-cyclopenta[a]phenanthren-16-yl)-1-methylpiperidin-1-ium bromide
  • 1-[(2beta,3alpha,5alpha,16beta,17beta)-3,17-Bis(acetyloxy)-2-(1-piperidinyl)androstan-16-yl]-1-methylpiperidinium Bromide
  • Vecuronium bromide USP/EP/BP
  • 50700-72-6 USP/EP/BP
  • Sodium Picosulfate Impurity 1
  • Vecuronim Bromide
  • Pancuronium bromide EP Impurity D
  • 50700-72-6
  • 5070-72-6
  • C34H57BrN2O4xH2O
  • C35H57Br2N2O4
  • C36H61NO4
  • C34H57N2O4Br
  • C34H57BrN2O4
  • CAMPRAL
  • API
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Steroid and Hormone
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