α1-39-Corticotropin (Schwein)

9061-27-2

CAS-Nr.: 9061-27-2

Bezeichnung:: α1-39-Corticotropin (Schwein)

Englisch Name:: Adrenocorticotropic hormone

Synonyma:: ACTH 1-39;CORTICOTROPIN A;ACTH (1-39), PORCINE;ADRENOCORTICOTROPIC HORMONE;ADRENOCORTICOTROPIC HORMONE;alpha1-39-Corticotropin (pig);PORCINE ADRENOCORTICOTROPIC HORMONE;AdrenocorticotrophicHormone,Porcine;ADRENOCORTICOTROPIC HORMONE, PORCINE;ADRENOCORTICOTROPIC HORMONE PORCINE PITUITARY

CBNumber:: CB3452071

Summenformel:: C210H314N56O57S

Molgewicht:: 4567.14616

MOL-Datei:: 9061-27-2.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 30

α1-39-Corticotropin (Schwein) Eigenschaften

storage temp.: −20°C

Aggregatzustand: powder

InChIKey: XFBDTKGDXZDJAN-WODOTNDISA-N

Sicherheit

Risiko- und Sicherheitserklärung
Gefahreninformationscode (GHS)

Kennzeichnung gefährlicher	Xn
R-Sätze:	20/21/22-40
S-Sätze:	22-36
WGK Germany	3

Bildanzeige (GHS)

Alarmwort

Warnung

Gefahrenhinweise

Code	Gefahrenhinweise	Gefahrenklasse	Abteilung	Alarmwort	Symbol	P-Code
H302	Gesundheitsschädlich bei Verschlucken.	Akute Toxizität oral	Kategorie 4	Warnung	src="/GHS07.jpg" width="20" height="20" />	P264, P270, P301+P312, P330, P501
H312	Gesundheitsschädlich bei Hautkontakt.	Akute Toxizität dermal	Kategorie 4	Warnung	src="/GHS07.jpg" width="20" height="20" />	P280,P302+P352, P312, P322, P363,P501
H332	Gesundheitsschädlich bei Einatmen.	Akute Toxizität inhalativ	Kategorie 4	Warnung	src="/GHS07.jpg" width="20" height="20" />	P261, P271, P304+P340, P312
H351	Kann vermutlich Krebs verursachen.	Karzinogenität	Kategorie 2	Warnung		P201, P202, P281, P308+P313, P405,P501

Sicherheit

P280

Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.

α1-39-Corticotropin (Schwein) Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:

R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut.
R40:Verdacht auf krebserzeugende Wirkung.

S-Sätze Betriebsanweisung:

S22:Staub nicht einatmen.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.

Indications

Adrenocorticotropic hormone (ACTH), or corticotropin, a peptide of 39 amino acids, is first synthesized as a larger precursor from which ACTH is derived by proteolytic cleavage. ACTH stimulates production of glucocorticoids from the adrenal cortex. Release of ACTH depends on diurnal rhythms with serum levels highest in the early morning. Secretion of this peptide also increases under stress. It is easier and less expensive to treat patients having adrenocortical insufficiency with glucocorticoid replacement therapy than it is to use ACTH. Therefore, use of ACTH (Acthar) is restricted to diagnosis; a shorter 24–amino acid analogue (Cosyntropin) is also used. Intravenous administration of ACTH should result in peak plasma levels of glucocorticoids within 30 to 60 minutes if the adrenal gland is functional. Prolonged administration of ACTH in a repository form, however, may be necessary to stimulate steroid production, because ACTH has long-term trophic effects on adrenal cells in addition to the rapid stimulation of steroid production. If the cause of steroid deficiency is at the level of the pituitary gland, ACTH should eventually stimulate steroid production.

Biologische Funktion

The main function of Adrenocorticotropic hormone (ACTH) is to regulate the glucocorticoid (steroid) hormone cortisol. Cortisol is released by the adrenal gland. It regulates blood pressure, blood sugar, the immune system, and the response to stress. This test can help find the causes of certain hormone problems

Health Hazard

Adrenocorticotropic Hormone (ACTH;Adrenocorticotropin; corticotropic hormone): (1)Maintenance of adrenal cortex;(2)Promotes secretion of steroids, oxidative phosphorylation in adrenal cortex;(3)Mobilizes and increases oxidation of free fatty acid in adipose tissue;(4)Increases gluconeogenesis in liver; increases cyclic adenosine monophosphate (AMP) in adrenal cortex;Decreases urea formation in liver.

Biochem/physiol Actions

Stimulates synthesis and secretion of glucocorticoids by adrenal cortex.

α1-39-Corticotropin (Schwein) Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

α1-39-Corticotropin (Schwein) Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 30)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
zhuzhou dingcheng meihei comestic co.,ltd	+undefined18873369619	dingchengbusiness8@163.com	China	241	58
Zibo Hangyu Biotechnology Development Co., Ltd	+86-0533-2185556 +8617865335152	Mandy@hangyubiotech.com	China	11013	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
Shanghai Longyu Biotechnology Co., Ltd.	+8615821988213	info@longyupharma.com	China	2531	58
Career Henan Chemica Co	+86-0371-86658258 15093356674;	laboratory@coreychem.com	China	30255	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	sales@sarms4muscle.com	China	10523	58
Hangzhou Go Top Peptide Biotech	0571-88211921	sales1@gotopbio.com	CHINA	2609	58
Alfa Chemistry	+1-5166625404	Info@alfa-chemistry.com	United States	21317	58
Hebei Miaoyin Technology Co.,Ltd	+86-17367732028 +86-17367732028	kathy@hbyinsheng.com	China	3582	58
Zhejiang Hangyu API Co., Ltd	+8617531972939	anna@api-made.com	China	2944	58

9061-27-2(α1-39-Corticotropin (Schwein))Verwandte Suche:

Corticotropin Tetracosactid Hexafluorokieselsure

adrenocorticotropic hormone from*porcine pituitar
alpha1-39-Corticotropin (pig)
ADRENOCORTICOTROPIC HORMONE FROM PORCINE PITUITARY
AdrenocorticotrophicHormone,Porcine
Adrenocorticotropic Hormone Fragment 1-39, Corticotropin A
PORCINE ADRENOCORTICOTROPIC HORMONE
CORTICOTROPIN A
ACTH 1-39
ACTH (1-39), PORCINE
ADRENOCORTICOTROPIC HORMONE
ADRENOCORTICOTROPIC HORMONE, PORCINE
ADRENOCORTICOTROPIC HORMONE PORCINE PITUITARY
ADRENOCORTICOTROPIC HORMONE
9061-27-2
C210H314N56O57S
Cytokines, Growth Factors and Hormones
Hormones
Pituitary Hormones
BioChemical
Adrenocorticotrophic Hormone (ACTH)
Cell Biology
Cell Signaling and Neuroscience