Endosidin 2

Endosidin 2 Struktur
1839524-44-5
CAS-Nr.
1839524-44-5
Englisch Name:
Endosidin 2
Synonyma:
Endosidin 2;Endosidin-2 (ES-2);3-fluoro-benzoicacid,(2E)-2-[(4-hydroxy-3-iodo-5-methoxyphenyl)methylene]hydrazide;Benzoic acid, 3-fluoro-, (2E)-2-[(4-hydroxy-3-iodo-5-methoxyphenyl)methylene]hydrazide
CBNumber:
CB34666449
Summenformel:
C15H12FIN2O3
Molgewicht:
414.17
MOL-Datei:
1839524-44-5.mol

Endosidin 2 Eigenschaften

Dichte
1.67±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
Löslichkeit
Soluble in DMSO (greater than 40 mg/ml), in DMF (up to 35 mg/ml) or in Ethanol (up to 10 mg/ml)
Aggregatzustand
powder
pka
7.75±0.36(Predicted)
Farbe
white to beige
Stabilität:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO, DMF or ethanol may be stored at -20°C for up to 1 month.
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung P264, P280, P305+P351+P338,P337+P313P
Sicherheit
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.

Endosidin 2 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Endosidin 2 binds to the EXO70 (exocyst component of 70 kDa) subunit of the exocyst complex, resulting in inhibition of exocytosis and endosomal recycling in both plant and human cells and enhancement of plant vacuolar trafficking. A valuable tool for exocytosis studies.

Biochem/physiol Actions

Endosidin2 is a cell-permeable benzylidene-benzohydrazide based compound that binds to the exocyst component of 70 kDa (EXO70) subunit of exocyst complex (Kd?= 253 μM for interaction with EXO70A1) and reduces exocytosis and endosomal recycling in plant and mammalian cells. Displays good aqueous stability. Endosidin2 has shown to disrupt the trafficking of proteins between the plasma membrane and endosome, which leads to enhanced trafficking to the vacuole for degradation. It is reported to inhibit the recycling of endocytosed transferrin to plasma membrane in HeLa cells, and can target multiple isoforms of EXO70 in mammals, resulting in misregulation of exocytosis.

Endosidin 2 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Endosidin 2 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 15)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Sigma-Aldrich 021-61415566 800-8193336
orderCN@merckgroup.com China 51471 80
BOC Sciences 16314854226
info@bocsci.com United States 9926 65
DC Chemicals 021-58447131 13564518121
sales@dcchemicals.com China 9414 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
sales@chemegen.com China 11289 58
TargetMol Chemicals Inc. 4008200310
marketing@tsbiochem.com China 24131 58
Shaoguan Qicheng Biotechnology Co., Ltd 18122215013
780229652@qq.com China 921 58
Nanjing Tengyi Biotechnology Co., Ltd 025-58851786 17714337195
sales@tybiochem.com China 4141 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627
customer_service@efebio.com China 8740 58
Yantai Lianhua Technology Co., Ltd 15552437730
1701654643@qq.com China 11525 58
United States Biological --
sales@advtechind.com United States 6106 58

1839524-44-5()Verwandte Suche:


  • Endosidin 2
  • Endosidin-2 (ES-2)
  • Benzoic acid, 3-fluoro-, (2E)-2-[(4-hydroxy-3-iodo-5-methoxyphenyl)methylene]hydrazide
  • 3-fluoro-benzoicacid,(2E)-2-[(4-hydroxy-3-iodo-5-methoxyphenyl)methylene]hydrazide
  • 1839524-44-5
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