Phytomenadion

Vitamin K1 Struktur
84-80-0
CAS-Nr.
84-80-0
Bezeichnung:
Phytomenadion
Englisch Name:
Vitamin K1
Synonyma:
PHYTONADIONE;PHYTOMENADIONE;PHYLLOQUINONE;Kativn K1;Phytomenadione (Vitamin K1);Kephton;K-Ject;Konakion;aquamephyton;Vitamin K1 5%
CBNumber:
CB3482555
Summenformel:
C31H46O2
Molgewicht:
450.7
MOL-Datei:
84-80-0.mol

Phytomenadion Eigenschaften

Schmelzpunkt:
−20 °C(lit.)
alpha 
D25 -0.28° (dioxane)
Siedepunkt:
140°C 0mm
Dichte
0.984 g/mL at 25 °C(lit.)
Brechungsindex
n20/D 1.527(lit.)
Flammpunkt:
>230 °F
storage temp. 
2-8°C
Löslichkeit
Chloroform (Sparingly), Dioxane (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
Aggregatzustand
viscous liquid
Farbe
Yellow to Dark Yellow
Wichte
0.984
Geruch (Odor)
odorless
Wasserlöslichkeit
Miscible with dehydrated alcohol, acetone, petroleum ether, hexane, dioxane, chloroform, ether, benzene and vegetable oils. Immiscible with water.
Sensitive 
Light Sensitive
Merck 
14,7380
BRN 
2568816
Stabilität:
Light Sensitive
InChIKey
MBWXNTAXLNYFJB-LKUDQCMESA-N
LogP
10.305 (est)
CAS Datenbank
84-80-0(CAS DataBase Reference)
NIST chemische Informationen
Phytonadione(84-80-0)
EPA chemische Informationen
Phylloquinone (84-80-0)
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
Kennzeichnung gefährlicher Xi
R-Sätze: 36/37/38
S-Sätze: 26-37/39-24/25
RIDADR  UN1170 - class 3 - PG 2 - Ethanol, solution
WGK Germany  2
RTECS-Nr. QJ5800000
1-8-10
TSCA  Yes
HS Code  29362900
Giftige Stoffe Daten 84-80-0(Hazardous Substances Data)
Bildanzeige (GHS) GHS hazard pictogramsGHS hazard pictograms
Alarmwort Achtung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H225 Flüssigkeit und Dampf leicht entzündbar. Entzündbare Flüssigkeiten Kategorie 2 Achtung GHS hazard pictogramssrc="/GHS02.jpg" width="20" height="20" /> P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
Sicherheit
P210 Von Hitze, heißen Oberflächen, Funken, offenen Flammen und anderen Zündquellenarten fernhalten. Nicht rauchen.
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.
P337+P313 Bei anhaltender Augenreizung: Ärztlichen Rat einholen/ärztliche Hilfe hinzuziehen.
P403+P235 An einem gut belüfteten Ort aufbewahren. Kühl halten.

Phytomenadion Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:

R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.

S-Sätze Betriebsanweisung:

S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.

Beschreibung

Vitamin K1 is a fat-soluble, dietary nutrient that is essential for the synthesis of proteins important for blood-clotting, bone metabolism, and cell growth. It is found in the photosynthetic tissues of green, leafy plants, where it acts as an electron acceptor forming part of the electron transport chain of Photosystem I. Vitamin K1 also serves as a precursor to vitamin K2 and is reported to exhibit anticancer activity in various cell lines.

Chemische Eigenschaften

Yellow Oil

Verwenden

vitamin K1

Allgemeine Beschreibung

Vitamin K1, also known as phylloquinone, consists of naphthalenoid and phytyl groups. Phylloquinone is present abundantly in photosynthetic plants and is a major dietary source. It is a fat-soluble vitamin.

mögliche Exposition

Phylloquinone is a dietary component essential for normal biosynthesis of several factors required for clotting of blood; as a therapeutic drug used to correct bleeding tendency; and as a food supplement.

Versand/Shipping

UN3249 Medicine, solid, toxic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials.

läuterung methode

Vitamin K1 is a yellow viscous oil, which can be distilled at high vacuum practically unchanged. It is insoluble in H2O, but soluble in common organic solvents. Store it in the dark under N2 as it is oxygen sensitive. It has  1cm 328 at 248nm. [Fieser et al. J Am Chem Soc 61 2557 1939, Hirschmann et al. J Am Chem Soc 76 4592 1954, Isler & Doebel Helv Chim Acta 27 225 1954, Beilstein 7 IV 2496.]

Inkompatibilitäten

Phylloquinone is photosensitive; decomposes in sunlight and is destroyed by alkali hydroxides and reducing agents such as hydrideds and active metals. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides.

Waste disposal

It is inappropriate and possibly dangerous to the environment to dispose of expired or waste drugs and pharmaceuticals by flushing them down the toilet or discarding them to the trash. Household quantities of expired or waste pharmaceuticals may be mixed with wet cat litter or coffee grounds, double-bagged in plastic, discard in trash. Larger quantities shall carefully take into consideration applicable DEA, EPA, and FDA regulations. If possible return the pharmaceutical to the manufacturer for proper disposal being careful to properly label and securely package the material. Alternatively, the waste pharmaceutical shall be labeled, securely packaged and transported by a state licensed medical waste contractor to dispose by burial in a licensed hazardous or toxic waste landfill or incinerator.

Phytomenadion Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Phytomenadion Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 544)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Wuhan Marco Pharmaceutical Technology Co., Ltd.
+86-86-18572802410 +8618572802410
sales@marcopht.com China 55 58
Shaanxi TNJONE Pharmaceutical Co., Ltd
+86-13474506593 +86-13474506593
sarah@tnjone.com China 794 58
Hangzhou FandaChem Co.,Ltd.
008657128800458; +8615858145714
fandachem@gmail.com China 9352 55
Hubei XinRunde Chemical Co., Ltd.
+8615102730682
bruce@xrdchem.cn CHINA 566 55
Nanjing Finetech Chemical Co., Ltd.
025-85710122 17714198479
sales@fine-chemtech.com CHINA 885 55
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795
ivan@atkchemical.com China 32480 60
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418679 +86-18949832763
info@tnjchem.com China 2989 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3620 58
career henan chemical co
+86-0371-86658258
sales@coreychem.com China 29914 58
SHANDONG ZHI SHANG CHEMICAL CO.LTD
+86 18953170293
sales@sdzschem.com China 2931 58

84-80-0(Phytomenadion)Verwandte Suche:


  • kativn
  • Kinadion
  • Mephyton
  • Monodion
  • Mono-Kay
  • Phyllochinon
  • Phythyl-menadion
  • Phytylmenadione
  • Synthex P
  • synthexp
  • theta-(e)]]-a-[thet
  • trans-Phylloquinone
  • Vitamin K1 1% powder
  • phylloguinone
  • PHYTONADIONE (PHYLLOQUINONE)
  • VITAMIN K1 (NATURAL) (USP) (PHYTONADIONE)
  • Vitamin K1(>99.5%Cis-K1<1.0%)
  • Vitamin K1(>99.5%Cis-K1<5.0%)
  • 2-Methyl-3-phytyl-1,4-naphthoquinone, 3-Phytylmenadione, Phylloquinone, VitaminK1(20), VitaminK1
  • 2-Methyl-3-phytyl-1,4-naphthoquinone, 3-Phytylmenadione, Phylloquinone, VitaminK1(20)
  • Vitamin K1 Oll [Phyto (Me) Nadione (Phylloguinone)]
  • hytomenadione
  • hytonadione
  • Vitamin K1 5% powder
  • Vitamin K1(>99.0%Cis-K1≤21.0%)
  • 3-Phytylmenadione 2-Methyl-3-(3,7,11,15-tetramethyl-2-hexadecenyl)-1,4-naphthalenedione
  • VitaminK1,2-Methyl-3-phytyl-1,4-naphthoquinone, 3-Phytylmenadione, Phylloquinone, VitaminK1(20)
  • Vitamin K1 100mg [84-80-0]
  • Phytonadione (500 mg) (Vitamin K1)
  • Vitamin K1-[2H7] (Phytonadione)
  • 2',3'-t
  • 2-Methyl-3-[(2E,7R,11R)-3,7,11,15-tetraMethyl-2-hexadecenyl]-1,4-naphthalenedione
  • 2-Methyl-3-phytyl-1,4-naphthoquinone Phylloquinone
  • ,r*-(e)))-
  • [r-[r*,R*-(E)]]-2-Methyl-3-(3,7,11,15-tetramethyl-2-hexadecenyl)-1,4-napthalenedione
  • [r-[r*,R*-(E)]]-2-Methyl-3-(3-7,11,15-tetramethyl-2-hexadecenyl)-1,4-naphthalenedione
  • 1,4-Naphthalenedione, 2-methyl-3-(3,7,11,15-tetramethyl-2-hexadecenyl)-
  • 1,4-Naphthalenedione, 2-methyl-3-(3,7,11,15-tetramethyl-2-hexadecenyl)-, [R-[R*,R*-(E)]]-
  • 1,4-Naphthoquinone, 2-methyl-3-phytyl-
  • 2',3'-trans-Vitamin K1
  • 2’,3’-trans-vitamink1
  • 2-methyl-3-(3,7,11,15-tetramethyl-2-hexadecenyl)-4-naphthalenedione
  • 2-Methyl-3-[(2E)-3,7,11,15-tetramethyl-2-hexadecenyl]naphthoquinone
  • 2-Methyl-3-phythyl-1,4-naphthochinon
  • 2-Methyl-3-phytyl-1,4-naphthochinon
  • 2-Methyl-3-phytyl-1,4-napthoquinone
  • 2-methyl-3-phytyl-4-naphthoquinone
  • VITAMIN K1
  • VITAMIN K1(25)
  • 4-naphthalenedione,2-methyl-3-(3,7,11,15-tetramethyl-2-hexadecenyl)-(r-(r*
  • 4-Naphthalenedione,2-methyl-3-(3,7,11,15-tetramethyl-2-hexadecenyl)-,[R-[R*,R*-(E)]]-1
  • 4-naphthalenedione,2-methyl-3-(3,7,11,15-tetramethyl-2-hexadecenyl)-[thet
  • alpha-Phylloquinone
  • Antihemorrhagic vitamin
  • antihemorrhagicvitamin
  • Aqua Mephyton
  • Aqua-Mephytin
  • Combinal K1
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