HISPIDIN

555-55-5

CAS-Nr.: 555-55-5

Englisch Name:: HISPIDIN

Synonyma:: Hispidine;Hispidin - CAS 555-55-5 - Calbiochem;6-(3,4-Dihydroxystyryl)-4-hydroxy-2-pyrone;6-(3,4-Dihydroxystyryl)-4-hydroxy-2H-pyran-2-one;(E)-6-(3,4-Dihydroxystyryl)-4-hydroxy-2H-pyran-2-one;4-hydroxy-6-(3,4-dihydroxystyryl)-2-pyrone (hispidine);2-[(E)-2-(3,4-dihydroxyphenyl)ethenyl]-6-hydroxy-4-pyranone;6-[(E)-2-(3,4-Dihydroxyphenyl)vinyl]-4-hydroxy-2H-pyran-2-one;(E)-6-[2-(3,4-Dihydroxyphenyl)ethenyl]-4-hydroxy-2H-pyran-2-one;6-[(1E)-2-(3,4-Dihydroxyphenyl)ethenyl]-4-hydroxy-2H-pyran-2-one

CBNumber:: CB3500046

Summenformel:: C13H10O5

Molgewicht:: 246.22

MOL-Datei:: 555-55-5.mol

Request For Quotation

Eigenschaften Sicherheit Verwendungswort Produktionsfirma 64

HISPIDIN Eigenschaften

Schmelzpunkt:: 312-315℃

Siedepunkt:: 500.5±50.0 °C(Predicted)

Dichte: 1.657

storage temp.: -20°C

Löslichkeit: DMSO: >10 mg/mL

pka: 4.90±0.30(Predicted)

Aggregatzustand: solid

Farbe: yellow to brown

maximale Wellenlänge (λmax): 369nm(MeOH)(lit.)

Sicherheit

Risiko- und Sicherheitserklärung
Gefahreninformationscode (GHS)

WGK Germany	3
HS Code	2932.20.3000

Bildanzeige (GHS)

Alarmwort

Warnung

Gefahrenhinweise

Code	Gefahrenhinweise	Gefahrenklasse	Abteilung	Alarmwort	Symbol	P-Code
H317	Kann allergische Hautreaktionen verursachen.	Sensibilisierung der Haut	Kategorie 1A	Warnung	src="/GHS07.jpg" width="20" height="20" />	P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H319	Verursacht schwere Augenreizung.	Schwere Augenreizung	Kategorie 2	Warnung	src="/GHS07.jpg" width="20" height="20" />	P264, P280, P305+P351+P338,P337+P313P

Sicherheit

P280	Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P305+P351+P338	BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.

HISPIDIN Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Hispidin is a polyphenol originally isolated from P. hispidus that has diverse biological activities, including antioxidant, anti-inflammatory, and cytoprotective properties. In a trolox equivalent antioxidant capacity (TEAC) assay, hispidin scavenges radicals at 14.47 equivalents of trolox . It inhibits transcriptional activity of NF-κB, decreases inducible nitric oxide synthase (iNOS) expression, and decreases the generation of reactive oxygen species (ROS) in LPS-induced macrophage RAW 264.7 cells. Hispidin inhibits apoptosis and increases insulin secretion in hydrogen peroxide-treated RINm5F pancreatic β-cells. It inhibits protein kinase C β (PKCβ; IC₅₀ = 2 μM) with no activity against alkaline phosphatase. Hispidin also inhibits β-secretase (BACE1; IC₅₀ = 4.9 μM) and prolyl endopeptidase (PE; IC₅₀ = 16 μM) but not other serine proteases when used at a concentration of 40 μM (0.6, 0, 8.2, and 3.1% inhibition of chymotrypsin, trypsin, elastase, and tumor necrosis factor-α converting enzyme (TACE), respectively).

Verwenden

Hispidin is a naturally occuring precursor to fungal luciferin responsible for luminosity in mushrooms.

Definition

ChEBI: Fungal metabolite first found in basidiomycete Inonotus hispidus (formerly Polyporus hispidus).

Allgemeine Beschreibung

Hispidin is a phenolic compound, that is obtained from a medicinal mushroom, Phellinus linteus.

HISPIDIN Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

HISPIDIN Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 64)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21695	55
Nanjing Finetech Chemical Co., Ltd.	025-85710122 17714198479	sales@fine-chemtech.com	CHINA	885	55
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	47465	58
Finetech Industry Limited	+86-27-87465837 +8618971612321	info@finetechnology-ind.com	China	9571	58
Dayang Chem (Hangzhou) Co.,Ltd.	571-88938639 +8617705817739	info@dycnchem.com	CHINA	52867	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
GIHI CHEMICALS CO.,LIMITED	+8618058761490	info@gihichemicals.com	China	49999	58
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	masar@topule.com	China	8474	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43348	58

555-55-5()Verwandte Suche:

Ethylamin

6-[(E)-2-(3,4-Dihydroxyphenyl)vinyl]-4-hydroxy-2H-pyran-2-one
4-hydroxy-6-(3,4-dihydroxystyryl)-2-pyrone (hispidine)
(E)-6-[2-(3,4-Dihydroxyphenyl)ethenyl]-4-hydroxy-2H-pyran-2-one
6-(3,4-Dihydroxystyryl)-4-hydroxy-2H-pyran-2-one
6-(3,4-Dihydroxystyryl)-4-hydroxy-2-pyrone
6-[(1E)-2-(3,4-Dihydroxyphenyl)ethenyl]-4-hydroxy-2H-pyran-2-one
Hispidine
2-[(E)-2-(3,4-dihydroxyphenyl)ethenyl]-6-hydroxy-4-pyranone
Hispidin - CAS 555-55-5 - Calbiochem
2H-Pyran-2-one, 6-[(1E)-2-(3,4-dihydroxyphenyl)ethenyl]-4-hydroxy-
(E)-6-(3,4-Dihydroxystyryl)-4-hydroxy-2H-pyran-2-one
Endogenous Metabolite,inhibit,anti-dementia,anti-diabetic,fungal,properties,PKC,Hispidin,Protein kinase C,Inhibitor,anti-oxidant,anti-cancer,metabolite
555-55-5