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OXIDIZED NIFEDIPINE

OXIDIZED NIFEDIPINE Struktur
67035-22-7
CAS-Nr.
67035-22-7
Englisch Name:
OXIDIZED NIFEDIPINE
Synonyma:
B 4759;BAY-b-4759;Nifedipine-1;Dehydro Nifedipine;Nifidipine Impurity A;Nitrophenyl nifedipine;Nifedipine impurity A CRS;Nifedipine impurity A (EP);Divalproex Sodium Impurity 1;Azilsartan medoxomil impurity308
CBNumber:
CB3505238
Summenformel:
C17H16N2O6
Molgewicht:
344.32
MOL-Datei:
67035-22-7.mol
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OXIDIZED NIFEDIPINE Eigenschaften

Schmelzpunkt:
100-105 °C
Siedepunkt:
443.7±45.0 °C(Predicted)
Dichte
1.284±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
Löslichkeit
Chloroform (Slightly), Methanol (Slightly)
Aggregatzustand
powder
pka
1.55±0.29(Predicted)
Farbe
yellow
EPA chemische Informationen
3,5-Pyridinedicarboxylic acid, 2,6-dimethyl-4-(2-nitrophenyl)-,3,5-dimethyl ester (67035-22-7)
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
Kennzeichnung gefährlicher Xi
R-Sätze: 41
S-Sätze: 26-39
WGK Germany  2
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Achtung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H318 Verursacht schwere Augenschäden. Schwere Augenschädigung Kategorie 1 Achtung GHS hazard pictogramssrc="/GHS05.jpg" width="20" height="20" /> P280, P305+P351+P338, P310
Sicherheit
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.

OXIDIZED NIFEDIPINE Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:

R41:Gefahr ernster Augenschäden.

S-Sätze Betriebsanweisung:

S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S39:Schutzbrille/Gesichtsschutz tragen.

Beschreibung

Dehydro nifedipine is an active metabolite of nifedipine , a calcium channel blocker present in formulations used to treat hypertension and angina. Dehydro nifedipine is formed when nifedipine is metabolized by the cytochrome P450 (CYP) isomers CYP3A4 and CYP3A5. Dehydro nifedipine inhibits glucose uptake in PC-12 cells with an IC50 value of 130 μM.

Chemische Eigenschaften

Pale Yellow Solid

Verwenden

Oxidized nifedipine has been used for apoptotic signaling studies in dopaminergic neurons.

OXIDIZED NIFEDIPINE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

OXIDIZED NIFEDIPINE Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 112)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Accela ChemBio Inc. 		(+1)-858-699-3322
info@accelachem.com United States 19965 58
Standardpharm Co. Ltd. 		86-714-3992388
overseasales1@yongstandards.com United States 14336 58
Shaanxi Dideu Medichem Co. Ltd 		+86-029-81148696 +8615536356810
 1047@dideu.com China 3527 58
Career Henan Chemica Co 		+86-0371-86658258 15093356674;
 laboratory@coreychem.com China 30255 58
ANHUI WITOP BIOTECH CO., LTD 		+8615255079626
 eric@witopchemical.com China 23556 58
CR Corporation Lomited
fred.wen@crcorporation.cn CHINA 12069 58
Hangzhou Huarong Pharm Co., Ltd. 		571-86758373 +8613588754946
 sales@huarongpharm.com CHINA 3149 58
sgtlifesciences pvt ltd 		+8617013299288
 dj@sgtlifesciences.com China 12382 58
Alfa Chemistry 		+1-5166625404
Info@alfa-chemistry.com United States 21317 58
China National Standard Pharmaceutical Corporation Limited 		+8615391658522
 overseasales@yongstandards.com China 11927 58

67035-22-7()Verwandte Suche:

3-Aminocrotonamid Dimethyl-2,6-dimethyl-4-(3-nitrophenyl)pyridin-3,5-dicarboxylat Methyl-3-aminocrotonat 1,4-Dihydro-2,6-dimethyl-4-(2-ni-trophenyl)-3,5-pyridindicarbon-säure-dimethylester 2,3,6-Trimethylpyridin Dimethylpyridin-3,5-dicarboxylat 3,4,5-Trimethylpyridin
  • Nifedipine Nitrophenylpyridine Analog
  • dimethyl 2,6-dimethyl-4-(2-nitrophenyl)pyridine-3,5-dicarboxylate
  • dimethyl2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylate
  • 2,6-Dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3,5-Dimethyl Ester
  • B 4759
  • Dehydro Nifedipine
  • 2,6-Dimethyl-4-(2-nitrophenyl)pyridine-3,5-dicarboxylic acid dimethyl ester
  • 4-(2-Nitrophenyl)-2,6-dimethylpyridine-3,5-dicarboxylic acid dimethyl ester
  • BAY-b-4759
  • Nitrophenyl nifedipine
  • Nifedipine-1
  • Dimethyl 2,6-Dimethyl-4-(2-nitrophenyl)-3,5-pyridined
  • Nifedipine Impurity Ⅰ:2,6-Dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3,5-Dimethyl Ester
  • 2,6-Dimethyl-4-(2′-nitrophenyl)-3,5-pyridinecarboxylic acid dimethyl ester, Oxidized Nifedipine
  • Divalproex Sodium Impurity 1
  • Nifedipine impurity A (EP)
  • Dimethyl 4-(2-nitrophenyl)-2,6-dimethylpyridine-3,5-dicarboxylate
  • Nifedipine Impurity Ⅰ（Dimethyl 2,6-Dimethyl-4-(2-Nitrophenyl)pyridine-3,5-Dicarboxylate）
  • Nifedipine impurity A CRS
  • Dimethyl 2,6-Dimethyl-4-(2-nitrophe
  • Nifedipine EP Impurity A/Dehydro Nifedipine
  • 3,5-Pyridinedicarboxylic acid, 2,6-dimethyl-4-(2-nitrophenyl)-, 3,5-dimethyl ester
  • Nifidipine Impurity A
  • Nifedipine EP Impurity A (Nifedipine nitrophenylpyridine analogue)
  • Azilsartan medoxomil impurity308
  • DehydronifedipineQ: What is Dehydronifedipine Q: What is the CAS Number of Dehydronifedipine Q: What is the storage condition of Dehydronifedipine Q: What are the applications of Dehydronifedipine
  • Nifedipine Impurity Ⅰ:2,6-Dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3,5-Dimethyl Ester
  • Nifedipine nitrophenylpyridine Analogue
  • dimethyl 2,6-dimethyl-4-(2-nitrophenyl)pyridine-3,5-dicarboxylate (nitrophenylpyridine analogue)
  • _x000b_Dimethyl 2,6-Dimethyl-4-(2-nitrophenyl)-3,5-pyridined
  • Nifedipine EP impurity A Dimethyl 2,6-dimethyl-4-(2-nitrophenyl)pyridine-3,5- dicarboxylate (nitrophenylpyridine analogue)
  • 67035-22-7
  • 34432
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals
  • Various Metabolites and Impurities
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