9-Fluor-11β,17,21-trihydroxy-16β-methylpregna-1,4-dien-3,20-dion-17,21-di(propionat)

Betamethasone 17,21-dipropionate Struktur
5593-20-4
CAS-Nr.
5593-20-4
Bezeichnung:
9-Fluor-11β,17,21-trihydroxy-16β-methylpregna-1,4-dien-3,20-dion-17,21-di(propionat)
Englisch Name:
Betamethasone 17,21-dipropionate
Synonyma:
BETAMETHASONE DIPROPIONATE;BetaMethasone dipropionat;diprolene;diprosone;Betamethasone 17;S 3440;Psorion;Maxivate;diprosis;Diprophos
CBNumber:
CB3676725
Summenformel:
C28H37FO7
Molgewicht:
504.6
MOL-Datei:
5593-20-4.mol

9-Fluor-11β,17,21-trihydroxy-16β-methylpregna-1,4-dien-3,20-dion-17,21-di(propionat) Eigenschaften

Schmelzpunkt:
178 °C
alpha 
D26 +65.7° (dioxane)
Siedepunkt:
603.2±55.0 °C(Predicted)
Dichte
1.1481 (estimate)
Brechungsindex
69 ° (C=1, Dioxane)
storage temp. 
2-8°C
Löslichkeit
Practically insoluble in water, freely soluble in acetone and in methylene chloride, sparingly soluble in ethanol (96 per cent).
pka
12.87±0.70(Predicted)
Farbe
White to Pale Yellow
Merck 
1180
InChIKey
CIWBQSYVNNPZIQ-JCOVECCMSA-N
SMILES
C([C@]1([C@H](C[C@@]2([H])[C@]3([H])CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C)C)OC(=O)CC)(=O)COC(=O)CC |&1:1,2,4,6,16,18,20,23,r|
CAS Datenbank
5593-20-4(CAS DataBase Reference)
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
S-Sätze: 22-24/25
WGK Germany  2
RTECS-Nr. TU4058000
HS Code  29372290
Toxizität LD50 ipr-mus: 103 mg/kg NIIRDN 6,753,82
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Achtung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H373 Kann die Organe schädigen bei längerer oder wiederholter Exposition. Spezifische Zielorgan-Toxizität (wiederholte Exposition) Kategorie 2 Warnung P260, P314, P501
Sicherheit
P202 Vor Gebrauch alle Sicherheitshinweise lesen und verstehen.
P260 Dampf/Aerosol/Nebel nicht einatmen.
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P308+P313 BEI Exposition oder falls betroffen: Ärztlichen Rat einholen/ärztliche Hilfe hinzuziehen.
P405 Unter Verschluss aufbewahren.
P501 Inhalt/Behälter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen.

9-Fluor-11β,17,21-trihydroxy-16β-methylpregna-1,4-dien-3,20-dion-17,21-di(propionat) Chemische Eigenschaften,Einsatz,Produktion Methoden

S-Sätze Betriebsanweisung:

S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.

Chemische Eigenschaften

Betamethasone 17,21-dipropionate is Pale Yellow Foam

Verwenden

Betamethasone 17,21-dipropionate is used as anti-inflammatory and antibacterial ointment for dermatosis.

Definition

Betamethasone 17,21-dipropionate is a steroid ester that is betamethasone in which the hydroxy hydrogens at positions 17 and 21 are replaced by propanoyl groups. It is used in combination with calcipotriene hydrate, a synthetic vitamin D analogue, for the topical treatment of plaque psoriasi in adult patients.

Sicherheitsprofil

Poison by subcutaneous andintraperitoneal routes. An experimental teratogen. Otherexperimental reproductive effects. When heated todecomposition it emits toxic fumes of F-.

9-Fluor-11β,17,21-trihydroxy-16β-methylpregna-1,4-dien-3,20-dion-17,21-di(propionat) Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


9-Fluor-11β,17,21-trihydroxy-16β-methylpregna-1,4-dien-3,20-dion-17,21-di(propionat) Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 410)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
APOLLO HEALTHCARE RESOURCES
+6596580999
sales@apollo-healthcare.com.sg Singapore 400 58
Nanjing Shizhou Biotechnology Co., Ltd
+86-15850508050 +86-15850508050
sean.lv@synzest.com China 323 58
Hebei Dangtong Import and export Co LTD
+8615632927689
admin@hbdangtong.com China 991 58
Hebei Kangcang new material Technology Co., LTD
+8619133911216
Jany1001@kangcang.com.cn China 338 58
Shaanxi TNJONE Pharmaceutical Co., Ltd
+86-13474506593 +86-13474506593
sarah@tnjone.com China 848 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
info@tianfuchem.com China 21695 55
Hubei XinRunde Chemical Co., Ltd.
+8615102730682
bruce@xrdchem.cn CHINA 566 55
career henan chemical co
+86-0371-86658258
sales@coreychem.com China 29914 58
Hubei Jusheng Technology Co.,Ltd.
18871490254
linda@hubeijusheng.com CHINA 28180 58
Xiamen AmoyChem Co., Ltd
+86-592-6051114 +8618959220845
sales@amoychem.com China 6387 58

5593-20-4(9-Fluor-11β,17,21-trihydroxy-16β-methylpregna-1,4-dien-3,20-dion-17,21-di(propionat))Verwandte Suche:


  • BETAMETHASONE 17,21-DI-PROPIONATE
  • BETAMETHASONE 17-ALPHA,21-DIPROPIONATE
  • 1,4-PREGNADIEN-9-ALPHA-FLUORO-16-BETA-METHYL-11-BETA, 17,21-TRIOL-3,20-DIONE 17,21-DIPROPIONATE
  • 9ALPHA-FLUORO-16BETA-METHYL-11BETA,17ALPHA,21-TRIHYDROXY-1,4-PREGNADIENE-3,20-DIONE 17,21-DIPROPIONATE
  • Betamethasonediproprionate
  • 9--Fluoro-16--methyl-11,17,21-trihydroxy-1,4-pregnadiene-3,20-dione17,21-dipropionate
  • BETANMETHASONE DIPROPIONATE
  • BETAMETHASONEDIPROPIONATE,MICRONIZEDPOWDER,USP
  • Diprophos
  • Maxivate
  • Pregna-1,4-diene-3,20-dione, 9-fluoro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)-, (11β,16β)-
  • Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17,21-trihydroxy-16β-methyl-, 17,21-dipropionate (7CI, 8CI)
  • Psorion
  • Rinderon DP
  • S 3440
  • Sch 11460
  • β-Methasone 17,21-dipropionate
  • 9alpha-Fluoro-11beta,17alpha,21-trihydroxy-16beta-methyl-1,4-pregnadiene-3,20-dione 17,21-Dipropionate
  • 17,21-Di(propionyloxy)-9-fluoro-11β-hydroxy-16β-methylpregna-1,4-diene-3,20-dione
  • [(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-(2-propanoyloxyacetyl)-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate
  • [(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-(2-propanoyloxyethanoyl)-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate
  • propionic acid [(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-3-keto-10,13,16-trimethyl-17-(2-propionyloxyacetyl)-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] ester
  • Betamethasone 17,21-dipropionate,9α-Fluoro-16β-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione 17,21-dipropionate
  • Betamethasone Dipropionate (125 mg)
  • Betamethasone 17,21-
  • 9a-fluoro-16b-methyl-11b,17a,21-trihydroxy-1,4-pregnadiene-3,20-dione 17,21-dipropionate
  • Betamethasone dipropionate for peak identification
  • Betamethasone dipropionate for system suitability
  • 17,21 betaMethasone dipropionate ester
  • diproderm
  • diprosis
  • 9-fluoro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17,21-di(propionate)
  • Betanmethasone Dipronate
  • Pregna-1,4-Diene-3,20-Dione,9-Fluoro-11-Hydroxy-16-Methyl-17,21-Bis(1-Oxopropoxy)-,(11Beta,16Beta)-
  • (11-beta,16-beta)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione-17,21-dipropionate
  • Betamethaasone Dipropionate
  • 99% High Purity Raw Powder Betamethason 17, 21-Dipropionate CAS 5593-20-4
  • Betamethasone dipropionate (B1040000)Q: What is Betamethasone dipropionate (B1040000) Q: What is the CAS Number of Betamethasone dipropionate (B1040000)
  • Betamethasone dipropionate for peak identification (Y0001416)
  • Betamethasone dipropionate for system suitability A (Y0001925)
  • Betamethasone DipropionateQ: What is Betamethasone Dipropionate Q: What is the CAS Number of Betamethasone Dipropionate Q: What is the storage condition of Betamethasone Dipropionate
  • Betamethasone Dipropionate (1067704)
  • AT-13387 lactate
  • ATI-13387A
  • ATI-13387AU
  • propanoic acid [2-[(8R,9S,10R,11S,13S,14R,16S,17R)-8-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-(1-oxopropoxy)-6,7,9,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] ester
  • Betamethasone 17,21-dipropionate, ≥97.0%
  • Betamethasone 17,21-dipropionate(5593-20-4)
  • Betamethasone dipropionate for peak identification CRS
  • Betamethasone 17,21-Dipropionate >
  • Betamethasone dipropionate CRS
  • Diprolene AF
  • Betamethasone dipropionate for system suitability A
  • (8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-(2-(propionyloxy)acetyl)-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl propionate
  • Anhydrous Beclometasone Dipropionate
  • Betamethasone dipropionate solution in Acetonitrile, 100μg/mL
  • Pregna-1,4-diene-3,20-dione,9-fluoro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)-, (11b,16b)-
  • Betamethasone 17,21-dipropionate USP/EP/BP
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