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α-Hydroxy-β,β-dimethyl-γ-butyrolacton Produkt Beschreibung

D-(-)-PANTOLACTONE Struktur
599-04-2
CAS-Nr.
599-04-2
Bezeichnung:
α-Hydroxy-β,β-dimethyl-γ-butyrolacton
Englisch Name:
D-(-)-PANTOLACTONE
Synonyma:
Pantolacton;PANTOLACTONE;PANTOLACTONE-D;Pantoiclactone;Pantoyllactone;D-PANTOLACTONE;Pantoyl lactone;Pentoyl lactone;(R)-Pantolacton;Pantolyl lactone
CBNumber:
CB3748921
Summenformel:
C6H10O3
Molgewicht:
130.14
MOL-Datei:
599-04-2.mol

α-Hydroxy-β,β-dimethyl-γ-butyrolacton Eigenschaften

Schmelzpunkt:
91 °C(lit.)
Siedepunkt:
120-122 °C15 mm Hg(lit.)
Dichte
1.1066 (rough estimate)
Brechungsindex
-50.8 ° (C=2, H2O)
Flammpunkt:
120-122°C/15mm
storage temp. 
2-8°C
pka
13.12±0.40(Predicted)
Aggregatzustand
Crystals or Crystalline Powder
Farbe
White
Optische Aktivität
[α]25/D 49.8°, c = 2 in H2O
Wasserlöslichkeit
almost transparency
Sensitive 
Hygroscopic
Merck 
14,7013
BRN 
80957
InChIKey
SERHXTVXHNVDKA-BYPYZUCNSA-N
CAS Datenbank
599-04-2(CAS DataBase Reference)
EPA chemische Informationen
Pantolactone (599-04-2)

Sicherheit

S-Sätze: 22-24/25
WGK Germany  1
3-10
TSCA  Yes
HS Code  29322090

α-Hydroxy-β,β-dimethyl-γ-butyrolacton Chemische Eigenschaften,Einsatz,Produktion Methoden

S-Sätze Betriebsanweisung:

S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.

Chemische Eigenschaften

WHITE CRYSTALLINE POWDER OR CRYSTALS

Verwenden

D-(-)-PANTOLACTONE is an important intermediate in the synthesis of pantothenic acid as well as a degradation product of pantothneic acid in the liver. Causes disorientation and hypothermia, and prevents phenamine-induced hyperthermia.

Verwenden

D-(-)-Pantolactone is a chiral auxiliary used in many asymmetric synthesis reactions.
It can be used as a chiral starting material to synthesize:
  • An insect sex pheromone named 1S,2S,3R-1-acetoxymethyl-2,3,4,4-tetrameth-ylcyclopentane.
  • (-)-Enantiomer of (R)-8-hydroxy-4,7,7-trimethyl-7,8-dihydrocyclopenta[e]isoindole-1,3(2H,6H)-dione, a norsesquiterpene alkaloid.
  • A bicyclic diterpene named isofregenedadiol.

Allgemeine Beschreibung

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

läuterung methode

Recrystallise the lactone from Et2O/pet ether, diisopropyl ether or *C6H6/pet ether and sublime it at 25o/0.0001mm. It hydrolyses readily to the hydroxy-acid and racemises when heated above 145o. The Brucine salt has m 211-212o (from EtOH). [Kuhn & Wieland Chem Ber 73 1134 1940, and Stiller et al. J Am Chem Soc 62 1779 1940, Bental & Tishler J Am Chem Soc 68 1463 1946, Beilstein 18/1 V 22.]

α-Hydroxy-β,β-dimethyl-γ-butyrolacton Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


α-Hydroxy-β,β-dimethyl-γ-butyrolacton Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 229)Lieferanten
Firmenname Telefon Fax E-Mail Land Produktkatalog Edge Rate
Shanghai Time Chemicals CO., Ltd.
+8618017249410 +86-021-57951555
+86-021-57951555 jack.li@time-chemicals.com China 1807 55
career henan chemical co
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sales@coreychem.com China 29953 58
Accela ChemBio Inc.
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Hebei Guanlang Biotechnology Co., Ltd.
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Hubei xin bonus chemical co. LTD
86-13657291602
027-59338440 linda@hubeijusheng.com CHINA 23035 58
Shandong chuangyingchemical Co., Ltd.
18853181302
sale@chuangyingchem.com CHINA 5917 58
Standardpharm Co. Ltd.
86-714-3992388
overseasales1@yongstandards.com United States 14344 58
Chongqing Chemdad Co., Ltd
+86-13650506873
sales@chemdad.com CHINA 37282 58
HENAN BON INDUSTRIAL CO.,LTD
0371-55170695
info@hnbon.com CHINA 26742 58
CONIER CHEM AND PHARMA LIMITED
86-18523575427
sales@conier.com China 47498 58

599-04-2(α-Hydroxy-β,β-dimethyl-γ-butyrolacton)Verwandte Suche:


  • (R)-()-β,β-Dimethyl-α-hydroxy-γ-butyrolactone
  • (R)-(-)-DIHYDRO-3-HYDROXY-4,4-DIMETHYL-2(3H)-FURANONE
  • (R)-DIHYDRO-3-HYDROXY-4,4-DIMETHYL-2(3H)-FURANONE
  • (R)-(-)-BETA,BETA-DIMETHYL-ALPHA-HYDROXY-GAMMA-BUTYROLACTONE
  • (R)-(-)-PANTOLACTONE
  • (R)-(-)-ALPHA-HYDROXY-BETA,BETA-DIMETHYL-GAMMA-BUTYROLACTONE
  • R(-)-3,3-DIMETHYL-2-HYDROXY-GAMMA-BUTYROLACTONE
  • R(-)-2-HYDROXY-3,3-DIMETHYL-GAMMA-BUTYROLACTONE
  • PANTOIC ACID GAMMA-LACTONE
  • PANTOLACTONE
  • PANTOLACTONE-D
  • 2(3H)-Furanone, dihydro-3-hydroxy-4,4-dimethyl-, (R)-
  • 2(3H)-Furanone, dihydro-3-hydroxy-4,4-dimethyl-, D-(-)-
  • 4-dimethyl-dihydro-3-hydroxy-(theta)-2(3h)-furanon
  • D-(-)-Pantoic acid lactone
  • D-(-)-Pantolyl lactone
  • dihydro-3-hydroxy-4,4-dimethyl-,(R)-2(3H)-Furanone
  • Dihydro-4,4-dimethyl-3-hydroxy-2(3H)-furanone
  • -Hydroxy-,-dimethyl-butyrolactone
  • Pantoiclactone
  • Pantolyl lactone
  • Pantothenic lactone
  • Pantoyl lactone
  • Pantoyllactone
  • Pentoyl lactone
  • Pentoyl lactone clene
  • D-()-Pantolactone,(R)-()-α-Hydroxy-β,β-dimethyl-γ-butyrolactone, (R)-()-β,β-Dimethyl-α-hydroxy-γ-butyrolactone, (R)-()-Pantolactone, Pantoic acid γ-lactone
  • Pan-acid lactone
  • (-)-2-Hydroxy-3,3-diMethyl-γ-butyrolactone
  • (3R)-Dihydro-3-hydroxy-4,4-diMethyl-2(3H)-furanone
  • (3R)-Tetrahydro-3-hydroxy-4,4-diMethylfuran-2-one
  • (R)-(-)-Dihydro-3-hydroxy-4,4-dimethyl-2(3H)-furanone D-(-)-2-Hydroxy-3,3-dimethyl-gamma-butyrolactone D-(-)-Pantoyl Lactone
  • Dexpanthenol Lactone IMpurity
  • Dihydro-3-hydroxy-4,4-dimethyl-2(3H)-furanone
  • D-(-)-Pantolactone 99%
  • (R)-3-Hydroxy-4,4-dimethyldihydrofuran-2(3H)-one
  • (R)-Pantolacton
  • Dexpanthenol Impurity 1
  • (3R)-3-hydroxy-4,4-dimethyloxolan-2-one
  • 2,4-DIHYDROXY-3,3-DIMETHYLBUTYRIC ACID GAMMA-LACTONE
  • ALPHA-HYDROXY-BETA,BETA-DIMETHYL-GAMMA-BUTYROLACTONE
  • D-(-)-PANTOYL LACTONE
  • D-PANTOYL LACTONE
  • D-PANTOIC ACID G-LACTONE
  • (-)-D-PANTOLACTONE
  • D-(-)-PANTOLACTONE
  • D-PANTOLACTONE
  • D-ALPHA-HYDROXY-BETA,BETA-DIMETHYL-GAMMA-BUTYROLACTONE
  • D-1-HYDROXY-2,2-DIMETHYL-3-BUTYROLACTONE
  • D-(-)-2-HYDROXY-3,3-DIMETHYL-GAMMA-BUTYROLACTONE
  • D-(-)-DIHYDRO-3-HYDROXY-4,4-DIMETHYL-2(3H)-FURANONE
  • (R)-N-Pantolactone
  • (R)-Pantoyl lactone
  • alpha-Hydroxy-beta,beta-dimethyl-alpha-butyrolactone
  • D-MINUS-PANTOYLLACTONE
  • D-(-)-PANTOYL LACTONE 98+%
  • D-(-)-Pantanolactone
  • D-(-)-Pantolactone,99%
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