Reduktase, Glutathion-
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- CAS-Nr.
- 9001-48-3
- Bezeichnung:
- Reduktase, Glutathion-
- Englisch Name:
- EC 1.6.4.2
- Synonyma:
- GR;GLUTATHIONE REDUCTASE;GR TYPE VI;GR TYPE II;EC 1.8.1.7;EC 1.6.4.2;EC: 1.6.4.2;E.C. 1.8.1.7;GSH reductase;GSSG reductase
- CBNumber:
- CB3770126
- Summenformel:
- NULL
- Molgewicht:
- 0
- MOL-Datei:
- Mol file
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Reduktase, Glutathion- Eigenschaften
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Achtung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H334 |
Kann bei Einatmen Allergie, asthmaartige Symptome oder Atembeschwerden verursachen. |
Sensibilisierung der Atemwege |
Kategorie 1 |
Achtung |
![GHS hazard pictograms]() src="/GHS08.jpg" width="20" height="20" /> |
P261, P285, P304+P341, P342+P311,P501 |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P284 |
Atemschutz tragen. |
| P501 |
Inhalt/Behälter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
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Reduktase, Glutathion- Chemische Eigenschaften,Einsatz,Produktion Methoden
S-Sätze Betriebsanweisung:
S24/25:Berührung mit den Augen und der Haut vermeiden.
Verwenden
Human glutathione reductase has been used in:
- glutathione reductase activity assay
- oxidative stress analysis
- redox assays
Allgemeine Beschreibung
Glutathione reductase (GLR1) exists in mitochondrial and cytoplasmic isoforms. It shares sequence and structural homology to thioredoxin reductase, and is a flavin-containing oxidoreductase. Its active site is composed of a redox-active disulphide, and it requires NADPH for its catalytic activity. It is a widely present enzyme and is found in plants, bacteria, yeast, mice and humans.
Biochem/physiol Actions
Glutathione reductase IGR) is a crucial flavoenzyme in the antioxidant defense system. Reduced glutathione (GSH) is used by glutathione peroxidase to detoxify hydrogen peroxide and in the process is converted to oxidized glutathione (GSSG). The GSSG is then recycled back to GSH by glutathione reductase (GR) using NADPH that is then converted to NADP+. The regenerated GSH is then available to detoxify more hydrogen peroxide. The enzyme uses FAD as a cofactor. GR and glutathione peroxidase may inhibit lipid peroxidation by functioning as antioxidant enzymes in sperm. Glutathione reductase shares a structural motif with a number of other proteins including aspartyl proteases, citrate synthase, EF hands, hemoglobins, lipocalins, and α/β hydrolases. GR is stimulated by melatonin and is reportedly irreversibly inhibited by a number of oxygen radical generating systems.
Reduktase, Glutathion- Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Reduktase, Glutathion- Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 107)Lieferanten
9001-48-3(Reduktase, Glutathion-)Verwandte Suche:
Tris(2,2,6,6-tetramethylheptan-3,5-dionato-O,O')europium
Kupfer(II)-4-oxopent-2-en-2-olat
2-Methylpropylisocyanid
(Ethylenbis(nitrilomethylidyn)-2,2'-diphenolato)cobalt(II)
Dichloro(ethylendiamin)platin
Ethylisocyanacetat
(Pentan-2,4-dionato-O,O')silber
Phenylselenol
Methylisocyanacetat
Aluminiumtris(2,4-pentandionato-O,O')
Benzylisocyanid
Tris(pentan-2,4-dionato)eisen(II)
(p-Toluolsulfonyl)methylisocyanid
Tris(2,2,6,6-tetramethylheptan-3,5-dionato-O,O')dysprosium
1,1,3,3-Tetramethylbutylisocyanat
Glutathion
N-Butylisocyanid
- NAD[P]H: OXIDIZED-GLUTATHIONE OXIDOREDUCTASE
- NAD[P]H: OXIDIZED-GLUTATHIONE OXIDOREDUCTASE TYPE II
- NAD[P]H: OXIDIZED-GLUTATHIONE OXIDOREDUCTASE TYPE VI
- GR TYPE II
- GR TYPE VI
- NADP-dependent glutathione reductase
- NADPH-glutathione reductase
- NADPH-GSSG reductase
- E.C. 1.8.1.7
- EC 1.8.1.7
- Glutathione disulfide oxidoreductase
- Glutathione S-reductase
- GSH reductase
- GLUTATHIONE REDUCTASE TYPE II
- GLUTATHIONE REDUCTASE TYPE VI
- GLUTATHIONE REDUCTASE, YEAST
- EC 1.6.4.2
- EC: 1.6.4.2
- Glutathione Reductase bakers yeast (S. cerevisiae)
- glutathione reductase from baker'S yeast
- Reductase, glutathione
- GLUTATHIONE REDUCTASE TYPE VI FROM*SPINA CH
- GLUTATHIONE REDUCTASE TYPE II CRUDE*FROM WHEAT GERM
- GLUTATHIONE REDUCTASE FROM BAKER'S YEAST , ~100 U/MG
- GLUTATHIONE REDUCTASE FROM BAKER'S &
- GlutathioneReductaseExYeast(E.C.1.6.4.2)
- Glutathionereductaseexyeast
- glutathione reductase from baker's yeast (s. cerevisiae)
- glutathione reductase from spinach
- glutathione reductase from wheat germ
- Glutathione Reductase from baker's yeast (S. cerevisiae),GR, NAD(P)H:oxidized-glutathione oxidoreductase
- Glutathione Reductase from spinach,GR, NAD(P)H: oxidized-glutathione oxidoreductase
- Glutathione reductase (NAD(P)H) from Yeast, 50% glycerol solution
- GR, (NAD(P)H): oxidized-glutathione oxidoreductase
- GR/Glutathione Reductase froM baker's yeast
- Glutathione Reductase human
- GSSG reductase
- Glutathione Reductase from bovine intestinal mucosa
- Glutathione reductase from E. coli, Recombinant
- Native Spinach Glutathione Reductase
- Native Wheat germ Glutathione Reductase
- Native Bakers yeast (S. cerevisiae) Glutathione Reductase
- Glutathione Reductase from Human, Recombinant
- Glutathione Reductase, from Yeast[GR]
- Glutathionereductase, 189units/mg protein
- GR
- GLUTATHIONE REDUCTASE
- 9001-48-3
- General Metabolic Enzymes A-H
- General Metabolic Enzymes
- Metabolomics
- BioChemical
- enzyme
