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Prednisolon Produkt Beschreibung

CAS-Nr.50-24-8
Bezeichnung:Prednisolon
Englisch Name:Prednisolone
Synonyma:
deltaf;solone;steran;prednis;ulacort;dicortol;eazolind;hydeltra;predonin;Steaglate
CBNumber:CB4109000
Summenformel:C21H28O5
Molgewicht:360.44
MOL-Datei:50-24-8.mol
Prednisolon physikalisch-chemischer Eigenschaften
Schmelzpunkt:: 240 °C (dec.)(lit.)
Siedepunkt:: 412.46°C (rough estimate)
alpha : D25 +102° (dioxane)
Dichte: 1.0963 (rough estimate)
Brechungsindex: 100 ° (C=1, Dioxane)
Flammpunkt:: 2℃
storage temp. : -20°C Freezer
Löslichkeit: Very slightly soluble in water, soluble in ethanol (96 per cent) and in methanol, sparingly soluble in acetone, slightly soluble in methylene chloride. It shows polymorphism (5.9).
Aggregatzustand: powder
Merck : 14,7721
BRN : 1354103
InChIKey: OIGNJSKKLXVSLS-VWUMJDOOSA-N
CAS Datenbank: 50-24-8(CAS DataBase Reference)
EPA chemische Informationen: Pregna-1,4-diene- 3,20-dione, 11,17,21-trihydroxy-, (11.beta.)-(50-24-8)
Sicherheit
Kennzeichnung gefährlicher: Xn,C,F
R-Sätze:: 22-34-11
S-Sätze:: 22-45-36/37/39-26-16
RIDADR : UN 2811 6.1 / PGIII
WGK Germany : 3
RTECS-Nr.: TU4152000
HS Code : 29379000
Giftige Stoffe Daten: 50-24-8(Hazardous Substances Data)

Prednisolon Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R22:Gesundheitsschädlich beim Verschlucken.
R34:Verursacht Verätzungen.
R11:Leichtentzündlich.
S-Sätze Betriebsanweisung:
S22:Staub nicht einatmen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S16:Von Zündquellen fernhalten - Nicht rauchen.
Chemische Eigenschaften
Crystalline Solid
Verwenden
Synthetic corticosteroid; metabolically interconvertible with prednisone
Verwenden
glucocorticoid
Verwenden
substance P antagonists (SPA). It mediates its effect by acting on neurokinin 1 receptor
Definition
ChEBI: A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.
Trademarks
Cortalone(Halsey); Delta-Cortef (Pharmacia & Upjohn); Fernisolone(Ferndale); Meti-Derm (Schering); Prelone (Muro); Prelone(Teva); Sterane (Pfizer).
Allgemeine Beschreibung
Prednisolone,Δ1-hydrocortisone,11β,17,21-trihydroxypregna-1,4-diene-3,20-dione, hasless salt-retention activity than hydrocortisone, but some patients have more frequently experiencedcomplications such as gastric irritation and peptic ulcers.Because of low MC activity, it cannot be used alone for adrenalinsufficiency. Prednisolone is available in varioussalts and esters to maximize its therapeutic utility:
Prednisolone acetate, USP (21-acetate)
Prednisolone sodium phosphate, USP (21-sodiumphosphate)
Prednisolone sodium succinate, USP (21-sodiumsuccinate)
Prednisolone tebutate, USP (21-tebutate).
Hazard
Causes sodium retention; may have side effects similar to cortisone.
Sicherheitsprofil
A poison by intravenous and subcutaneous routes. Moderately toxic by ingestion and intraperitoneal routes. Human teratogenic effects by an unspecified route: developmental abnormalities of the central nervous system; effects on embryo or fetus: fetal death, extra embryonic structures. Human reproductive effects by an unspecified route: stdlbirth. An experimental teratogen. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes.
Prednisolon Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Hydrocortison
Downstream Produkte
Prednicarbat 11β,17,21-Trihydroxypregna-1,4-dien-3,20-dion-21-methansulfonat
Prednisolon Anbieter Lieferant Produzent Hersteller Vertrieb Händler.      Global( 312)Lieferanten     
Firmenname Telefon Fax E-Mail Land Produktkatalog Edge Rate
Capot Chemical Co.,Ltd.
+86 (0)571-855 867 18
+86 (0)571-858 647 95sales@capotchem.com China 19947 60
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925Abel@chembj.com CHINA 3210 55
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 22064 58
Beijing Cooperate Pharmaceutical Co.,Ltd.
+86-10-60279497 +86(0)15646567669
+86-10-60279497sales01@cooperate-pharm.com CHINA 1530 55
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693info@tianfuchem.com CHINA 20743 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733sales@mainchem.com CHINA 32606 55
PI & PI BIOTECH INC.
020-81716320
020-81716319Sales@pipitech.com CHINA 2543 55
Hubei XinRunde Chemical Co., Ltd.
+8615102730682; +8618874586545
02783214688bruce@xrdchem.cn CHINA 548 55
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418684 18949823763
86-0551-65418684info@tnjchem.com China 1747 55
Meihua Biological Technology Co.,Ltd
15175972705
031145896235sales@hbmeihua.cn CHINA 213 58
 
50-24-8(Prednisolon)Verwandte Suche:
Prednison-21-acetat Prednisolon-21-acetat Prednison Paramethason-21-acetat Prednyliden Budesonid Fluprednisolon Methylprednisolon-21-acetat Flunisolid Prednisolon Meprednison Hydrocortison-21-(natriumsuccinat) Methylprednisolon Prednisolon-21-(dinatriumphosphat) Prednisone(prednisoni) PREDNISOLONE BASE 11β,17,21-Trihydroxypregn-4-en-3,20-dion-17-butyrat Hydrocortison-21-acetat
Budesonide Impurity 8 Prednoisolone PREDNISOLONE GLUCOCORTICOID PREDNISOLONE VETRANAL, 250 MG DY-DEHYDROHYDROCORTISONE USP DY-DEHYDROCORTISOL USP METACORTANDRALONE USP SCHERISOLON USP PREDNISOLONE EPP(CRM STANDARD) PREDNISOLONE MM(CRM STANDARD) PREDNISOLONE USP PrednisoloneSeriesBase (11b)-11,17,21-Trihydroxy-pregna-1,4-diene-3,20-dione Steaglate 1,4-pregnadiene-11β,17α,21-triol-3,20-dione PREDNISOLONE,ANHYDROUS,MICRONIZED,USP PREDNISOLONE,ANHYDROUS,POWDER,USP prednisoone 11BETA 17,21-TRIHYDROXYPREGNA-1,4-DIENE-3,20-DIONE USP 1,4-Pregnadien-11β,17α,21-triol-3,20-dione-2,4,6,6,21,21-D6 (11B)11,17,21-Trihydroxyprehna-1,4-dien-3,20-dione+ (11)-11,17,21-Trihydroxy-pregna-1,4-diene-3,20-dione 1,4-Pregnadiene-11β,17α,21-triol-3,20-dione, 1-Dehydrocortisol, 1-Dehydrohydrocortisone, 11β,17α,21-Trihydroxy-1,4-pregnadiene-3,20-dione Prednisolone, Anhydrous, Micronized Prednisolone, Anhydrous, Powder Precortansyl Prednisolone for system suitability (8S,9S,10R,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxy-1-oxoethyl)-10,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one DEHYDROHYDROCORTISONE HYDRODELTALONE METACORT AND RALONE METACORTANDROLONE 11B,17,21-TRIHYDROXYPREGNA-1,4-DIENE-3,20-DIONE 11BETA,17ALPHA,21-TRIHYDROXYPREGNA-1,4-DIENE-3,20-DIONE 11BETA 17,21-TRIHYDROXYPREGNA-1,4-DIENE-3,20-DIONE 11-BETA,17-ALPHA,21-HYDROXY-1,4-PREGNADIENE-3,20-DIONE 11BETA,17ALPHA,21-TRIHYDROXY-1,4-PREGNADIENE-3,20-DIONE 1-DEHYDROCORTISOL 1-DEHYDROHYDROCORTISONE 1,4-PREGNADIEN-11-B,17,21-TRIOL-3,20-DIONE 1,4-PREGNADIEN-11BETA,17ALPHA,21-TRIOL-3,20-DIONE 1,4-PREGNADIEN-11-BETA, 17,21-TRIOL-3,20-DIONE 1,4-PREGNADIENE-11B,17A,21-TRIOL-3,20-DIONE 1,4-PREGNADIENE-11BETA,17ALPHA,21-TRIOL-3,20-DIONE (8S,9S,10R,11S,13S,14S,17R)-11,17-DIHYDROXY-17-(2-HYDROXY-ACETYL)-10,13-DIMETHYL-6,7,8,9,10,11,12,13,14,15,16,17-DODECAHYDRO-CYCLOPENTA[A]PHENANTHREN-3-ONE SCHERISOLON STEROLONE PREDNISOLONE PRENOLONE (11beta)-11,17,21-trihydroxypregna-1,4-diene-3,20-dione 1,2-dehydrohydrocortisone 1,4-pregnadiene-3,20-dione-11-beta,17-alpha,21-triol 1,4-pregnadiene-3,20-dione-11beta,17alpha,21-triol (8S,9S,10R,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one (8S,9S,10R,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyethanoyl)-10,13-dimethyl-7 (8S,9S,10R,13S,14S,17R)-17-glycoloyl-11,17-dihydroxy-10,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one Prednisolone-d6 Hydrocortisone EP Impurity A
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