Sumatriptan
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- CAS-Nr.
- 103628-46-2
- Englisch Name:
- Sumatriptan
- Synonyma:
- gr43175;IMITREX;IMIGRAN;gr43175x;Sumatriptan;Imigran，Imitrex;SUMATRIPTAN BASE;SuMatriptan Maxalt;Sumatriptan (50 mg);Sumatriptan USP/EP/BP
- CBNumber:
- CB4135041
- Summenformel:
- C14H21N3O2S
- Molgewicht:
- 295.4
- MOL-Datei:
- 103628-46-2.mol
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Sumatriptan Eigenschaften
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H412 |
Schädlich für Wasserorganismen, mit langfristiger Wirkung. |
Langfristig (chronisch) gewässergefährdend |
Kategorie 3 |
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P273, P501 |
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| Sicherheit |
| P202 |
Vor Gebrauch alle Sicherheitshinweise lesen und verstehen. |
| P273 |
Freisetzung in die Umwelt vermeiden. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P308+P313 |
BEI Exposition oder falls betroffen: Ärztlichen Rat einholen/ärztliche Hilfe hinzuziehen. |
| P405 |
Unter Verschluss aufbewahren. |
| P501 |
Inhalt/Behälter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
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Sumatriptan Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Verwenden
Sumatriptan is a serotonin 5HT1-receptor agonist.
Definition
ChEBI: A sulfonamide that consists of N,N-dimethyltryptamine bearing an additional (N-methylsulfamoyl)methyl substituent at position 5. Selective agonist for a vascular 5-HT1 receptor s
btype (probably a member of the 5-HT1D family). Used (in the form of its succinate salt) for the acute treatment of migraine with or without aura in adults.
Allgemeine Beschreibung
Sumatriptan was the first triptan approved (1991) for theacute treatment of migraine headaches. It has the lowestoral bioavailability among all triptans because of its lowlipophilicity. The availability of many different dosageforms (i.e., an oral tablet, a SC injection, a nasal spray formulation,and a suppository) allows the flexibility of tailoringtherapy to the needs of the individual patients, thusmaking sumatriptans a very useful drug for an acute treatmentof migraine headaches. It also has a very fastonset of action via SC injection or nasal spray administration.However, sumatriptan is contraindicated withmonoamine oxidase inhibitors because it is primarily degradedby hepatic MAO-A. Thus, it may require frequentdosing as a result of its short duration of action to preventmigraine recurrence.
Sumatriptan Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Sumatriptan Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 214)Lieferanten
103628-46-2()Verwandte Suche:
- 3-[2-(DIMETHYLAMINO)ETHYL]-N-METHYL-1H-INDOLE-5-METHANESULFONAMIDE, SUCCINATE
- IMIGRAN
- IMITREX
- (3-[2-(Dimethylamino)ethyl]-1H-indol-5-yl)-N-methylmethanesulfonamide
- 3-(2-(dimethylamino)ethyl)-n-methyl-1h-indole-5-methanesulfonamid
- 3-[2-(Dimethylamino)ethyl]-N-methylindole-5-methanesulfonamide
- gr43175
- gr43175x
- SUMATRIPTAN BASE
- SumatriptanSuccinateBase
- 1H-Indole-5-methanesulfonamide, 3-2-(dimethylamino)ethyl-N-methyl-
- 4-HYDRAZINE-N-METHYLBENZENE METHANE SULFONAMIDE
- sumatriptan hemisuccinate
- Sumatriptan (base and/or unspecified salts)
- 1-[3-(2-Dimethylaminoethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide
- Sumatriptan
- Imigran，Imitrex
- [3-(2-Dimethylaminoethyl)-1H-indole-5-yl]-N-methylmethanesulfonamide
- Sumatriptan (50 mg)
- SuMatriptan Succinate Inj
- SuMatriptan Maxalt
- SuMatriptan IMpurity H
- Sumatriptan for system suitability CRS
- Sumatriptan USP/EP/BP
- SumatriptanQ: What is
Sumatriptan Q: What is the CAS Number of
Sumatriptan Q: What is the storage condition of
Sumatriptan
- Sumatriptan (1642154)
- methylene (2S,5R,6R)-6-[[(2R)-[[[(2S,5R,6R)-6-[[(2R)-
aminophenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-
1-azabicyclo[3.2.0]hept-2-yl]carbonyl]amino]-
phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-
azabicyclo[3.2.0]heptane-2-carboxylate (2S,5R)-3,3-dimethyl-4,4,7-trioxo-4λ6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate (ampicillin sultamicillin amide)
- 3-[2-(Dimethyl amino) ethyl -1H-indol-5-yl -N-methyl methane sulphonamide
- 103628-46-2
- 103628-48-2
- API's
- Sumatriptan
- Active Pharmaceutical Ingredients
