ANTI-GRB2

ANTI-GRB2 Struktur
CAS-Nr.
Englisch Name:
ANTI-GRB2
Synonyma:
ANTI-MI;Anti-bw;Anti-vit;Anti-ASH;ANTI-MITF;ANTI-GRB2;Protein Ash;Anti-MST084;Anti-Grb3-3;Anti-MSTP084
CBNumber:
CB4138446
Summenformel:
Molgewicht:
0
MOL-Datei:
Mol file

ANTI-GRB2 Eigenschaften

storage temp. 
-20°C
Aggregatzustand
buffered aqueous solution
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
S-Sätze: 23-24/25
WGK Germany  -
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung P264, P280, P305+P351+P338,P337+P313P
Sicherheit
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.

ANTI-GRB2 Chemische Eigenschaften,Einsatz,Produktion Methoden

S-Sätze Betriebsanweisung:

S23:Gas/Rauch/Dampf/Aerosol nicht einatmen(geeignete Bezeichnung(en) vom Hersteller anzugeben).
S24/25:Berührung mit den Augen und der Haut vermeiden.

Verwenden

Mouse monoclonal clone C5 anti-Microphthalmia antibody is used to tag serine phosphorylated and non-phosphorylated melanocytic isoforms of microphthalmia for detection and quantitation by techniques such as immunoblotting (doublet of 52-56 kDa), immunoprecipitation, immunohistochemistry on formalin-fixed paraffin embedded or frozen tissue sections, and gel shift. It is used as a probe to determine the roles of microphthalmia in the differentiation, development and survival of melanocytes and cells of the retinal pigment epithelium.

Allgemeine Beschreibung

Microphthalmia (Mi in mouse or MITF in human) is a basic helix-loop-helix-leucine zipper (BHLH–ZIP) transcription factor involved in the differentiation, development and survival of melanocytes and cells of the retinal pigment epithelium, i.e. cells responsible for hair, skin, and eye color. It activates the expression of the melanocyte specific genes tyrosinase and TRP1 (tyrosinase-related protein 1) by binding as a homo- or heterodimer to a symmetrical DNA sequence (E box) (5′-CATGTG-3′) located within the M box found in their promoters. Microphthalmia also appears to be involved in the differentiation of mast cells, osteoclasts, basophils and natural killer cells.
Microphthalmia is expressed in a limited number of cell types including heart, mast cells, osteoclast precursors, and melanocytes. There are a number of different isoforms of microphthalmia resulting from alternative splicing and alternative promotors. These isoforms differ at their amino-termini and in their expression patterns.

ANTI-GRB2 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


ANTI-GRB2 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 20)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Sigma-Aldrich 021-61415566 800-8193336
orderCN@merckgroup.com China 51471 80

  • MONOCLONAL ANTI-MICROPHTHALMIA
  • MICROPHTHALMIA (AB-1) MONOCLONAL ANTIBODY
  • ANTI-ASH/GRB2
  • ANTI-ASH/GRB-2, HUMAN
  • ANTI-MICROPHTHALMIA (AB-1)
  • ANTI-MICROPHTHALMIA (AB-1), HUMAN
  • ANTI-MICROPHTHALMIA (AB-1) MOUSE MAB
  • ANTI-MI
  • ANTI-MI (AB-1), HUMAN
  • ANTI-MI (AB-1) MOUSE MAB
  • ANTI-MITF
  • ANTI-MITF (AB-1), HUMAN
  • ANTI-MITF (AB-1) MOUSE MAB
  • ANTI-GRB2
  • ANTI-GRB2 (AB-2), HUMAN
  • ANTI-HUMAN GRB2
  • Monoclonal Anti-Grb-2 antibody produced in mouse
  • Monoclonal Anti-Microphthalmia antibody produced in mouse
  • Anti-GRB2 antibody produced in chicken
  • Adapter protein GRB2
  • Anti-GRB2 antibody produced in rabbit
  • Protein Ash
  • SH2/SH3 adapter GRB2
  • Anti-MST084
  • Anti-MSTP084
  • Anti-bw
  • Anti-MGC124309
  • Anti-MGC124310
  • Anti-vit
  • Anti-ASH
  • Anti-EGFRBP-GRB2
  • Anti-GRB2 antibody produced in goat
  • Anti-Grb3-3
  • Anti-Growth factor receptor-bound protein 2
  • GAntibodies for Kinase/Phosphatase Biology
  • Grb-2
  • Receptor Tyrosine Kinase Adaptor Protein Antibodies
  • Alphabetical Index
  • Antibodies
  • Clone Index
  • GAntibodies
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