LEUROSINE Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Vinqa rosea yields this complex dimeric alkaloid which forms colourless crystals
that are best purified by recrystallization from acetonitrile. It crystallizes with 8
moles of H20 and loses solvent when heated at In-5°C. It is also dextro?
rotatory with [α]
26D + n° (CHCI3)’ A crystalline SUlphate is known which has
m.p. 238-242°C (dec.) and [α]
D - 8.3° (MeOH). The N(b)-oxide is identical
with pleurosine (q.v.).
Verwenden
Vinleurosine is an antitumor compound derived from Vinca Rosea.
Einzelnachweise
Svoboda., J. Amer. Pharm. Assoc., 47,834 (1959)
Neuss et al., J. Amer. Chern. Soc., 81,4754 (1959)
Revised structure:
Neuss et al., Tetrahedron Lett., 783 (1968)
LEUROSINE Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
