Pizotifen
|
|
|
- CAS-Nr.
- 15574-96-6
- Bezeichnung:
- Pizotifen
- Englisch Name:
- Pizotifen
- Synonyma:
- Litec;bc105;BC 105;PIZOTIFEN;Pizotifan;Pizotylene;Pizotyline;Pizotifenum;Sandomigram;Sandomigran
- CBNumber:
- CB4230373
- Summenformel:
- C19H21NS
- Molgewicht:
- 295.44
- MOL-Datei:
- 15574-96-6.mol
|
Pizotifen Eigenschaften
- Schmelzpunkt:
- 140-142°C
- Siedepunkt:
- 436.7±45.0 °C(Predicted)
- Dichte
- 1.164±0.06 g/cm3(Predicted)
- storage temp.
- room temp
- Löslichkeit
- DMSO: ≥8mg/mL
- pka
- pKa 6.95 (Uncertain)
- Aggregatzustand
- powder
- Farbe
- White to Off-White
- Merck
- 14,7515
- CAS Datenbank
- 15574-96-6(CAS DataBase Reference)
- NIST chemische Informationen
- Pizotyline(15574-96-6)
Pizotifen Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
Chemische Eigenschaften
White to Off-White Solid
Verwenden
Serotonin antagonist structurally related to Cyproheptadine. Antimigraine; appetite stimulant.
Indications
Pizotifen, a potent antihistamine and antiserotonin
agent usually prescribed for migraine prophylaxis, has had reported success
in patients with polycythemia vera.
Definition
ChEBI: A benzocycloheptathiophene that is 9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thiophene 4-ylidene)-1-methylpiperidine which is joined from the 4 position to the 4 position of an N-methylpiperidine moiety b
a double bond. It is a sedating antihistamine, with strong serotonin antagonist and weak antimuscarinic activity. It is generally used as the malate salt for the treatment of migraine and the prevention of headache attacks during cluster periods.
Pizotifen Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Pizotifen Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 201)Lieferanten
15574-96-6(Pizotifen)Verwandte Suche:
Tetrahydrothiophen
Hexahydromethylphthalsureanhydrid
Methyl tetrahydrophthalic anhydride
2,2,6,6-Tetramethylpiperidin-4-ol
2-Benzothienylboronic acid
Tetramethylammonium hydroxide pentahydrate
Flurbiprofen
1-(4,4-Bis(4-fluorphenyl)butyl)-4-(4-chlor-3-(tri-fluormethyl)phe-nyl)-4-piperidinol
Apfelsure, Verbindung mit 4-(9,10-Dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-yliden)-1-methylpiperidin (1:1)
Cycloheptan
4,9-Dihydro-4-(1-methylpiperidin-4-yliden)-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-onfumarat
Ketotifen
Pizotifen
- Pizotylene
- PIZOTHIFENUM
- Pizotifenum
- Pizotyline (base and/or unspecified salts)
- 4-OXO-9,10-DIHYDRO-4H-BENZO(4,5) CYCLOHEPTO(1,2,B) THIOPHENE
- PIZOTIFEN
- 4-(9,10-Dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene)-1-methylpiperidine
- BC 105
- bc105
- Litec
- Piperidine, 4-(9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene)-1-methyl-
- piperidine,4-(9,10-dihydro-4h-benzo(4,5)cyclohepta(1,2-b)thien-4-ylidene)-1-me
- Pizotifan
- Pizotyline
- Pizotyline maleate
- Sandomigram
- Sandomigran
- Sandomygran
- Pizotyline-D3
- 4-(9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-ylidene)-1-methylpiperidine
- Pizotifen USP/EP/BP
- 4-(4,5-dihydrobenzo[1,2]cyclohepta[3,4-b]thiophen-10-ylidene)-1-methylpiperidine
- 15574-96-6
- 574-96-6
- C19H21NS
- Aromatics
- Heterocycles
- Intermediates & Fine Chemicals
- Pharmaceuticals
- Sulfur & Selenium Compounds
- Sandomigran, pizotyline
- Pizotifen
- Active Pharmaceutical Ingredients
