N-(2'-(S)-hydroxyarachidoyl)-D-erythro-sphingosine

1246298-48-5

CAS-Nr.: 1246298-48-5

Englisch Name:: N-(2'-(S)-hydroxyarachidoyl)-D-erythro-sphingosine

Synonyma:: 20:0(2S-OH) Ceramide;N-(2'-(S)-hydroxyarachidoyl)-D-erythro-sphingosine;N-(2'-(S)-hydroxyarachidoyl)-D-erythro-sphingosine;N-(2'-(S)-HYDROXYARACHIDOYL)-D-ERYTHRO-SPHINGOSINE;20:0(2S-OH) CERAMIDE;Eicosanamide, 2-hydroxy-N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-, (2S)-

CBNumber:: CB42719825

Summenformel:: C38H75NO4

Molgewicht:: 610.01

MOL-Datei:: 1246298-48-5.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 6

N-(2'-(S)-hydroxyarachidoyl)-D-erythro-sphingosine Eigenschaften

Siedepunkt:: 739.3±60.0 °C(Predicted)

Dichte: 0.939±0.06 g/cm3(Predicted)

storage temp.: -20°C

pka: 13.26±0.20(Predicted)

Sicherheit

N-(2'-(S)-hydroxyarachidoyl)-D-erythro-sphingosine Chemische Eigenschaften,Einsatz,Produktion Methoden

Allgemeine Beschreibung

Ceramides linked to 2-hydroxy fatty acids (hFA) are present in the surface epithelium of the skin. 20:0(2S-OH) Ceramide is a unique ceramide containing 20C long chain base fatty acid (arachidic acid)-with 2′-hydroxyl group in S configuration.

Biochem/physiol Actions

Hydroxy fatty acid (hFA)-sphingolipids help in formation and function of myelin. In addition, they also play a vital role in cell signaling, cell differentiation and apoptosis. In epidermis, hFA-ceramides aid in permeability barrier function. NAD(P)H-dependent enzyme, fatty acid 2-hydroxylase (FA2H) catalyzes the synthesis of hFA-ceramides. FA2H gene mutation leads to the development of neurological disorders such as leukodystrophy and spastic paraparesis in humans. hFA-ceramides help PM02734 (elisidepsin), an?antitumor drug to exhibit its activity.

N-(2'-(S)-hydroxyarachidoyl)-D-erythro-sphingosine Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

N-(2'-(S)-hydroxyarachidoyl)-D-erythro-sphingosine Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 6)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Creative Enzymes	1-516-855-7709	info@creative-enzymes.com	United States	8748	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	52927	58
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51471	80
Codow Chemical Co.,Ltd.	18620099427	amy@howeipharm.com	China	17698	55
Chengdu Dianchun Technology Co., Ltd	400-1166-196 18502815961	cdhxsj@163.com	China	14623	60

N-(2'-(S)-hydroxyarachidoyl)-D-erythro-sphingosine
20:0(2S-OH) Ceramide
N-(2'-(S)-HYDROXYARACHIDOYL)-D-ERYTHRO-SPHINGOSINE;20:0(2S-OH) CERAMIDE
Eicosanamide, 2-hydroxy-N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-, (2S)-
N-(2'-(S)-hydroxyarachidoyl)-D-erythro-sphingosine
1246298-48-5