ANTI-BETA-CATENIN

ANTI-BETA-CATENIN Struktur
CAS-Nr.
Englisch Name:
ANTI-BETA-CATENIN
Synonyma:
ANTI-BETA-CATENIN;ANTI-HUMAN BETA-CATENIN;ANTI-BETA-CATENIN (CORE);Monoclonal Anti-β-Catenin;DEPHOSPHO, AMINO ACIDS 27-37;ANTI-BETA-CATENIN (NT/EXON 2);MONOCLONAL ANTIBODY TO BETA-CATENIN;MONOCLONAL ANTI-BETA-CATENIN, CLONE 6F9;MONOCLONAL ANTI-BETA-CATENIN, CLONE 15B8;Monoclonal Anti-β-Catenin antibody produced in mouse
CBNumber:
CB4351678
Summenformel:
Molgewicht:
0
MOL-Datei:
Mol file

ANTI-BETA-CATENIN Eigenschaften

storage temp. 
-20°C

Sicherheit

WGK Germany  3

ANTI-BETA-CATENIN Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Monoclonal Anti-β-Catenin antibody produced in mouse has been used:
  • immunoblotting
  • immunohistochemistry
  • immunolabeling
  • immunofluorescence
  • immunocytochemical staining

Allgemeine Beschreibung

Monoclonal Anti-β-Catenin (mouse IgG1 isotype) is derived from the 15B8 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice. β-catenin belongs to the armadillo family and comprises the N-terminal region with 12 imperfect repeats?and a conserved C-terminal region. The locus 3p22.1 in the human chromosome harbors β-catenin gene. β-catenin shares 70% sequence identity to a protein encoded by Drosophila armadillo, a segment polarity gene. Both armadillo and β-catenin share considerable homology with plakoglobin, which has been proposed to be γ-catenin.

Biochem/physiol Actions

β-catenin is a prime component of the wingless (Wnt) pathway and plays a key role in gene expression during development. The homology between β-catenin and armadillo raised the possibility that β-catenin has a developmental signaling role in vertebrates. β-catenin mediates the interaction of the E-cadherin-catenin complex with the epidermal growth factor (EGF) receptor. β-catenin and plakoglobin are substrates for tyrosine phosphorylation following EGF stimulation of cells. β-catenin also associates with the tumor suppressor protein adenomatous polyposis coli (APC). Monoclonal antibody reacting specifically with β-catenin is an essential tool in defining the interactions and distributions of β-catenin and its relationships with other catenins and cadherins in various cells and tissues.

ANTI-BETA-CATENIN Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


ANTI-BETA-CATENIN Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 18)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Sigma-Aldrich 021-61415566 800-8193336
orderCN@merckgroup.com China 51471 80
Shanghai Yiyan Biotechnology Co. , Ltd. 021-69985186 13611928337
3427709316@qq.com China 7984 58

  • Monoclonal Anti-β-Catenin antibody produced in mouse
  • ANTI-HUMAN BETA-CATENIN
  • DEPHOSPHO, AMINO ACIDS 27-37
  • ANTI-BETA-CATENIN (NT/EXON 2)
  • ANTI-BETA-CATENIN (CORE)
  • ANTI-BETA-CATENIN
  • MONOCLONAL ANTIBODY TO BETA-CATENIN
  • MONOCLONAL ANTI-BETA-CATENIN, CLONE 15B8
  • MONOCLONAL ANTI-BETA-CATENIN, CLONE 6F9
  • Monoclonal Anti-β-Catenin
  • Monoclonal Anti-β-Catenin-Cy3 antibody produced in mouse
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  • Antibodies to Cytoskeleton
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  • Cell Biology
  • Clone Index
  • Neural Stem Cell Tracking
  • Neuronal Development
  • Tumor Growth Regulation
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