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2-(3,4-Dihydroxyphenyl)-7-(β-D-glucopyranosyloxy)-5-hydroxy-4H-1-benzopyran-4-on

Cynaroside Struktur
5373-11-5
CAS-Nr.
5373-11-5
Bezeichnung:
2-(3,4-Dihydroxyphenyl)-7-(β-D-glucopyranosyloxy)-5-hydroxy-4H-1-benzopyran-4-on
Englisch Name:
Cynaroside
Synonyma:
LUTEOLIN-7-O-GLUCOSIDE;luteoloside;PETUNIDIN;LUTEOLIN-7-GLUCOSIDE;Galuteolin;cinaroside;glucoluteolin;Luteolin 7-O-β-D-glucopyranoside;4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-7-(.beta.-D-glucopyranosyloxy)-5-hydroxy-;CYNAROSIDE
CBNumber:
CB4369516
Summenformel:
C21H20O11
Molgewicht:
448.38
MOL-Datei:
5373-11-5.mol
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2-(3,4-Dihydroxyphenyl)-7-(β-D-glucopyranosyloxy)-5-hydroxy-4H-1-benzopyran-4-on Eigenschaften

Schmelzpunkt:
256～258℃
storage temp. 
Sealed in dry,2-8°C
Löslichkeit
DMSO (Slightly), Methanol (Slightly)
Siedepunkt:
838.1±65.0 °C(Predicted)
Dichte
1.713±0.06 g/cm3(Predicted)
pka
6.10±0.40(Predicted)
Farbe
Yellow to Very Dark Yellow
Stabilität:
Hygroscopic
InChIKey
PEFNSGRTCBGNAN-QNDFHXLGSA-N
LogP
-0.090 (est)
CAS Datenbank
5373-11-5(CAS DataBase Reference)

Sicherheit

Kennzeichnung gefährlicher Xi
S-Sätze: 24/25
WGK Germany  3
RTECS-Nr. DJ3009400
HS Code  29389090

2-(3,4-Dihydroxyphenyl)-7-(β-D-glucopyranosyloxy)-5-hydroxy-4H-1-benzopyran-4-on Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Luteolin-7-O-glucoside is a flavonoid that has been found in many Chinese herbs with diverse biological activities. It reduces lactate dehydrogenase (LDH) and caspase-3 activities and production of reactive oxygen species (ROS) and increases cell viability and 14-3-3η protein levels in H9C2 cardiomyocytes after anoxia/reoxygenation injury. Luteoloside blocks 3C protease activity (IC50 = 0.36 mM) and reduces the cytopathic effect of enterovirus 71 in rhabdomyosarcoma cells (EC50 = 0.43 mM). It inhibits the growth of hepatocellular carcinoma (HCC) cells in vitro via reduction in ROS accumulation, caspase-1 activity, and expression of the NLRP3 inflammasome and reduces the number of lung metastases in an SMMC-7721 HCC mouse xenograft model when administered at a dose of 2 mg/kg. Luteoloside also reduces acanthosis and expression of epidermal differentiation markers in a mouse model of psoriasis induced by imiquimod .

Chemische Eigenschaften

Off-white powder

Verwenden

Luteolin 7-Glucoside is a strong antioxidant ant radical scavenger. Used in cancer prevention.

Definition

ChEBI: A glycosyloxyflavone that is luteolin substituted by a beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage.

2-(3,4-Dihydroxyphenyl)-7-(β-D-glucopyranosyloxy)-5-hydroxy-4H-1-benzopyran-4-on Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

2-(3,4-Dihydroxyphenyl)-7-(β-D-glucopyranosyloxy)-5-hydroxy-4H-1-benzopyran-4-on Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 264)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Hebei Yanxi Chemical Co., Ltd. 		+8617531190177
 peter@yan-xi.com China 5993 58
Shanghai Zheyan Biotech Co., Ltd. 		18017610038
zheyansh@163.com CHINA 3620 58
career henan chemical co 		+86-0371-86658258
sales@coreychem.com China 29914 58
Chengdu GLP biotechnology Co Ltd 		028-87075086 13350802083
 scglp@glp-china.com CHINA 1824 58
Chengdu Biopurify Phytochemicals Ltd. 		+8618080483897
 sales@biopurify.com China 3424 58
Nanjing Dolon Biotechnology Co.,Ltd. 		18905173768
sales@dolonchem.com CHINA 2972 58
Hubei Jusheng Technology Co.,Ltd. 		18871490254
linda@hubeijusheng.com CHINA 28180 58
Hubei xin bonus chemical co. LTD 		86-13657291602
linda@hubeijusheng.com CHINA 22968 58
BOC Sciences 		+1-631-485-4226
inquiry@bocsci.com United States 19553 58
Chongqing Chemdad Co., Ltd 		+86-023-61398051 +8613650506873
 sales@chemdad.com China 39916 58

5373-11-5(2-(3,4-Dihydroxyphenyl)-7-(β-D-glucopyranosyloxy)-5-hydroxy-4H-1-benzopyran-4-on)Verwandte Suche:

3,6-Bis[(4-chlor-2-phosphonophenyl)azo]-4,5-dihydroxynaphthalin-2,7-disulfonsure Glucosidase Amylase, Gluco- 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4-benzopyron (2R-trans)-2-(3,4-Dihydroxyphenyl)-2,3-dihydro-3,5,7-trihydroxy-4-benzopyron 2-(3,4-Dihydroxy-5-methoxyphenyl)-3,5,7-trihydroxy-1-benzopyryliumchlorid alkyl polyglucoside Diosmin Octylglucosid 2-(3,4-Dihydroxyphenyl)-7-(β-D-glucopyranosyloxy)-5-hydroxy-4H-1-benzopyran-4-on
  • LUTEOLIN-7-O-GLUCOSIDE 98+%
  • luteolin7-o-glucopyranoside
  • CYNAROSIDE
  • LUTEOLIN-7-O-GLUCOSIDE WITH HPLC
  • 7-β-D-Glucosylluteolin
  • Nephrocizin
  • Nephrocizine
  • Luteoloside，Cynaroside，Galuteolin，Glucoluteolin
  • Luteolin 7-β-D-glucopyranoside
  • Luteolin 7-b-glucoside
  • lCynaroside
  • Daphneflavonoloside
  • Flavopurposide
  • LUTEOLIN-7-GLUCOSIDE hplc
  • 2-(3,4-Dihydroxyphenyl)-5-hydroxy-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one
  • Luteolin 7-O-D-glucoside
  • LUTEOLIN-7-O-GLUCOSIDE(P)
  • Luteolin 7-beta-glucoside
  • Luteolin-7-O-D-glucopyranoside, froM Gentiana Macrophylla
  • Cynaroside Luteolin 7-O-D-glucoside
  • 4H-1-Benzopyran-4-one,2-(3,4-dihydroxyphenyl)-7-(b-D-glucopyranosyloxy)-5-hydroxy-
  • luteolin 7-O-beta-D-glucoside
  • 2-(3,4-dihydroxyphenyl)-7-(beta-d-glucopyranosyloxy)-5-hydroxy-4h-1-benzopyr
  • 4h-1-benzopyran-4-one,2-(3,4-dihydroxyphenyl)-7-(beta-d-glucopyranosyloxy)-5-h
  • 7-glucoluteolin
  • 7-glucosylluteolin
  • luteolin7-monoglucoside
  • Luteolin-7-O-D-glucopyranoside, 98%, from Gentiana macrophylla
  • 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-7-(β-D-glucopyranosyloxy)-5-hydroxy-
  • GLUCOLUTEOLIN; LUTEOLOSIDE; CINAROSIDE; LUTEOLIN 7-GLUCOSIDE;LUTEOLIN 7-O-Β-D-GLUCOSIDE
  • Luteolin-7-O-β-D-glucopyranoside, 98%, from Gentiana macrophylla Pall.
  • 2-(3,4-dihydroxyphenyl)-5-hydroxy-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one
  • luteolin7-O-β-D-glucoside
  • Cynaroside USP/EP/BP
  • 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-7-(.beta.-D-glucopyranosyloxy)-5-hydroxy-
  • luteoloside
  • LUTEOLIN-7-GLUCOSIDE
  • LUTEOLIN-7-O-GLUCOSIDE
  • Luteolin 7-O-β-D-glucopyranoside
  • Galuteolin
  • PETUNIDIN
  • cinaroside
  • glucoluteolin
  • Luteolin 7-β-D-Glucopyranoside
  • Cynaroside (Luteolin 7-glucoside)
  • Luteoloside (Cynaroside)
  • Luteoloside Luteolin 7-glucoside
  • 5373-11-5
  • 5375-11-5
  • 1268-79-8
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
  • Cofactor
  • Tetra-substituted Flavones
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