(1R,2S)-rel-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide hydrochloride
|
|
|
- CAS-Nr.
- 101152-94-7
- Englisch Name:
- (1R,2S)-rel-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide hydrochloride
- Synonyma:
- IXEL;F 2207;Dalcipran;TOLEDOMIN;cis-(+-)-d;MIDALCIPRAN;Milnacipran HCI;MILNACIPRAN HCL;Chiral Reagents;Milnacipran HCl (1)
- CBNumber:
- CB4423243
- Summenformel:
- C15H23ClN2O
- Molgewicht:
- 282.81
- MOL-Datei:
- 101152-94-7.mol
|
(1R,2S)-rel-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide hydrochloride Eigenschaften
- Schmelzpunkt:
- 179-1810C
- Flammpunkt:
- 9℃
- storage temp.
- 2-8°C
- Löslichkeit
- H2O: 19 mg/mL
- Aggregatzustand
- solid
- Farbe
- white
- Merck
- 14,6194
- CAS Datenbank
- 101152-94-7(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Kennzeichnung gefährlicher |
Xn,T,F |
|
|
| R-Sätze: |
22-39/23/24/25-23/24/25-11 |
|
|
| S-Sätze: |
7-16-36/37-45 |
|
|
| RIDADR |
UN 2811 6.1/PG 3 |
|
|
| WGK Germany |
3 |
|
|
| RTECS-Nr. |
GZ1014010 |
|
|
| HazardClass |
6.1 |
|
|
| PackingGroup |
III |
|
|
| HS Code |
29242990 |
|
|
| Toxizität |
LD50 orally in mice: 237 mg/kg (Bonnaud) |
|
|
| Bildanzeige (GHS) |
|
| Alarmwort |
Achtung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H301 |
Giftig bei Verschlucken. |
Akute Toxizität oral |
Kategorie 3 |
Achtung |
![GHS hazard pictograms]() src="/GHS06.jpg" width="20" height="20" /> |
P264, P270, P301+P310, P321, P330,P405, P501 |
|
| Sicherheit |
| P301+P310 |
BEI VERSCHLUCKEN: Sofort GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen. |
|
(1R,2S)-rel-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide hydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R22:Gesundheitsschädlich beim Verschlucken.
Chemische Eigenschaften
Crystalline Solid
Verwenden
Antidepressant. A selective norepinephrine and serotonin reuptake inhibitor approved for the management of fibromyalgia.
Allgemeine Beschreibung
Milnacipran, sold under the brand names Savella
?, Ixel
?, Dalcipran
?, or Toledomin, is a serotonin-norepinephrine reuptake inhibitor (SNRI) used in the treatment of depression. In 2009, the US Food and Drug Administration (FDA) approved milnacipran for management of the chronic pain disorder fibromyalgia, making it only the third drug approved in the US for this indication besides duloxetine and pregabalin.
Biologische Aktivität
Orally active 5-HT and noradrenalin re-uptake inhibitor (SNRI) (IC 50 values are 203 and 100 nM respectively) that displays no affinity at a range of other receptors. Causes adaptive changes to α 1 -adrenergic and 5-HT 2A serotonergic systems when administered repeatedly. Exhibits antidepressive and antinociceptive activities in vivo .
(1R,2S)-rel-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide hydrochloride Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
(1R,2S)-rel-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide hydrochloride Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 328)Lieferanten
101152-94-7()Verwandte Suche:
[4S-(4α,4aα,5aα,12aα)]-4,7-Bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxonaphthacen-2-carboxamidmonohydrochlorid
Terconazol
Mianserinhydrochlorid
Aciclovir
- cis-(+-)-2-(aminomethyl)-n,n-diethyl-1-phenylcyclopropanecarboxamidemonohydr
- cis-(+-)-d
- Milnacipran Hydrochloride (Subject to patent free)
- (1R,2S)-rel-2(Amino-methyl)-N,N-diethyl-1-phenyl-cyclopropanecarboxamide, Monohydrochloride
- Dalcipran
- F 2207
- IXEL
- (1R,2S)-REL-2-(AMINOMETHYL)-N,N-DIETHYL-1-PHENYLCYCLOPROPANECARBOXAMIDE HYDROCHLORIDE
- (1R,2S)-REL-2-(AMINOMETHYL)-N,N-DIMETHYL-1-PHENYLCYCLOPROPANECARBOXAMIDE HYDROCHLORIDE
- Milnacipran hydrochloride solution
- F 2207, Midalcipran, Toledomin, (1R,2S)-rel-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide monohydrochloride
- rel-2α*-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropane-1α*-carboxamide·hydrochloride
- rac Milnacipran Hydrochloride
- (1R*,2S*)-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamidehydrochloride
- Milnacipran HCI
- Milnacipran Hydrochloride Tablets
- Milnacipran HCl (1)
- TOLEDOMIN
- MILNACIPRAN HCL
- MILNACIPRAN HYDROCHLORIDE
- MIDALCIPRAN
- MIDALCIPRAN HYDROCHLORIDE
- 1-phenyl-1-(diethylaminocarbonyl)-2-(aminomethyl)cyclopropanehydrochloride
- 2-(aminomethyl)-n,n-diethyl-1-phenyl-cyclopropanecarboxamidmonohydrochlori
- 2-(aminomethyl)-N,N-diethyl-1-phenyl-1-cyclopropanecarboxamide hydrochloride
- Milnacipran-d5 HCl (and Enantiomer)
- Milancipran Hydrochloride
- MilnacipranHydrochloride>
- Milnacipran Hydrochloride (250 mg)
- Cyclopropanecarboxamide, 2-(aminomethyl)-N,N-diethyl-1-phenyl-, hydrochloride (1:1), (1R,2S)-rel-
- Milnacipran Hydrochloride Impurities
- Milnacipran hydrochlorideQ: What is
Milnacipran hydrochloride Q: What is the CAS Number of
Milnacipran hydrochloride Q: What is the storage condition of
Milnacipran hydrochloride Q: What are the applications of
Milnacipran hydrochloride
- Chiral Reagents
- Milnacipran hydrochloride, 98%, Serotonin and norepinephrine reuptake inhibitor
- RSYYMilnacipranhydrochloride
- Minapram hydrochloride
- 101152-94-7
- C15H22N2OHClC15H23ClN2O
- C15H23ClN2O
- NEGGRAM
- Amines
- Aromatics
- Chiral Reagents
- Antibiotic Explorer
- Intermediates & Fine Chemicals
- Pharmaceuticals
