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Butan-1,4-diol Produkt Beschreibung

1,4-Butanediol Struktur
110-63-4
CAS-Nr.
110-63-4
Bezeichnung:
Butan-1,4-diol
Englisch Name:
1,4-Butanediol
Synonyma:
BDO;1,4-BD;sucolb;diol14b;Sucol B;Diol 14B;Dabco BDO;Butanediol;agrisynthb1d;4-Butanediol
CBNumber:
CB4452184
Summenformel:
C4H10O2
Molgewicht:
90.12
MOL-Datei:
110-63-4.mol

Butan-1,4-diol Eigenschaften

Schmelzpunkt:
16 °C (lit.)
Siedepunkt:
230 °C (lit.)
Dichte
1.017 g/mL at 25 °C (lit.)
Dampfdichte
3.1 (vs air)
Dampfdruck
<0.1 hPa (20 °C)
Brechungsindex
n20/D 1.445(lit.)
Flammpunkt:
135 °C
storage temp. 
Store below +30°C.
pka
14.73±0.10(Predicted)
Aggregatzustand
Liquid
Farbe
Clear colorless
PH
7-8 (500g/l, H2O, 20℃)
Geruch (Odor)
Odorless
Explosionsgrenze
1.95-18.3%(V)
Wasserlöslichkeit
Miscible
Sensitive 
Hygroscopic
BRN 
1633445
Stabilität:
Stable. Combustible. Incompatible with strong oxidizing agents, mineral acids, acid chlorides, acid anhydrides.
InChIKey
WERYXYBDKMZEQL-UHFFFAOYSA-N
CAS Datenbank
110-63-4(CAS DataBase Reference)
NIST chemische Informationen
1,4-Butanediol(110-63-4)
EPA chemische Informationen
1,4-Butanediol (110-63-4)
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
Kennzeichnung gefährlicher Xn
R-Sätze: 22-67
S-Sätze: 36-23-24/25
WGK Germany  1
RTECS-Nr. EK0525000
Selbstentzündungstemperatur 698 °F
TSCA  Yes
HS Code  29053980
Giftige Stoffe Daten 110-63-4(Hazardous Substances Data)
Toxizität LD50 orally in Rabbit: 1525 mg/kg LD50 dermal Rabbit > 2000 mg/kg
Bildanzeige (GHS)
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitsschädlich bei Verschlucken. Akute Toxizität oral Kategorie 4 Warnung P264, P270, P301+P312, P330, P501
H336 Kann Schläfrigkeit und Benommenheit verursachen. Spezifische Zielorgan-Toxizität (einmalige Exposition) Kategorie 3 (Schläfrigkeit und Benommenheit) Warnung P261, P271, P304+P340, P312,P403+P233, P405, P501
Sicherheit
P261 Einatmen von Staub vermeiden.
P264 Nach Gebrauch gründlich waschen.
P264 Nach Gebrauch gründlich waschen.
P270 Bei Gebrauch nicht essen, trinken oder rauchen.
P330 Mund ausspülen.

Butan-1,4-diol Chemische Eigenschaften,Einsatz,Produktion Methoden

ERSCHEINUNGSBILD

FARBLOSE, VISKOSE FLüSSIGKEIT.

CHEMISCHE GEFAHREN

Reagiert mit starken Oxidationsmitteln.

ARBEITSPLATZGRENZWERTE

TLV nicht festgelegt (ACGIH 2005).
MAK nicht festgelegt (DFG 2005).

AUFNAHMEWEGE

Aufnahme in den Körper durch Inhalation der Dämpfe und durch Verschlucken.

INHALATIONSGEFAHREN

Nur ungenügende Angaben vorhanden über die Geschwindigkeit, mit der eine gesundheitsschädliche Konzentration in der Luft beim Verdampfen bei 20°C erreicht wird.

WIRKUNGEN BEI KURZZEITEXPOSITION

WIRKUNGEN BEI KURZZEITEXPOSITION:
Möglich sind Auswirkungen auf das Zentralnervensystem mit nachfolgender Narkose.

LECKAGE

Ausgelaufene Flüssigkeit möglichst in abdichtbaren Behältern sammeln. Reste mit viel Wasser wegspülen. Persönliche Schutzausrüstung: Atemschutzfilter für organische Gase und Dämpfe.

R-Sätze Betriebsanweisung:

R22:Gesundheitsschädlich beim Verschlucken.

S-Sätze Betriebsanweisung:

S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.

Chemische Eigenschaften

1,4-butanediol (1,4-BD) is a colorless, viscous liquid derived from butane by placement of alcohol groups at each end of its molecular chain and is one of four stable isomers of butanediol.the hydroxyl function of each end group of the Butanediol reacts with different mono- and bifunctional reagents: for example with dicarboxylic acids to polyesters, with diisocyanates to polyurethanes, or with phosgene to polycarbonates. 1.4-Butanediol (BDO) is a high-quality intermediate. BDO and its derivatives are widely used for producing plastics, solvents, electronic chemicals and elastic fibers. Additionally BDO is also a building block for the synthesis of polyesterpolyols and polyetherpolyols. BASF is the most significant producer of 1,4-Butanediol and its derivatives worldwide.

Verwenden

  1. Butanediol and its derivatives is used in a broad spectrum of applications in the chemical industry; amongst others in the manufacturing of technical plastics, polyurethanes, solvents, electronic chemicals and elastic fibres.
  2. 1,4-Butanediol is used in the synthesis of epothilones, a new class of cancer drugs. Also used in the stereoselective synthesis of (-)-Brevisamide.
  3. 1,4-Butanediol's largest use is within tetrahydrofuran (THF) production, used to make polytetramethylene ether glycol, which goes mainly into spandex fibers, urethane elastomers, and copolyester ethers.
  4. It is commonly used as a solvent in the chemical industry to manufacture gamma-butyrolactone and elastic fibers like spandex.
  5. It is used as a cross-linking agent for thermoplastic urethanes, polyester plasticizers, paints and coatings.
  6. It undergoes dehydration in the presence of phosphoric acid yielded teterahydrofuran, which is an important solvent used for various applications.
  7. It acts an intermediate and is used to manufacture polytetramethylene ether glycol (PTMEG), polybutylene terephthalate (PBT) and polyurethane (PU).
  8. It finds application as an industrial cleaner and a glue remover.
  9. 1,4-butanediol is also used as a plasticiser (e.g. in polyesters and cellulosics), as a carrier solvent in printing ink, a cleaning agent, an adhesive (in leather, plastics, polyester laminates and polyurethane footwear), in agricultural and veterinary chemicals and in coatings (in paints, varnishes and films).

Verwenden

butylene glycol is a solvent with good antimicrobial action. It enhances the preservative activity of parabens. Butylene glycol also serves as a humectant and viscosity controller, and to mask odor.

Verwenden

1,4-Butanediol is used to produce polybutyleneterephthalate, a thermoplastic polyester;and in making tetrahydrofuran, butyrolactones,and polymeric plasticizers.

Vorbereitung Methode

Methods of manufacturing:
The most prevalent 1,4-BD production route worldwide is BASF's Reppe process, which reacts acetylene and formaldehyde. Acetylene reacts with two equivalents of formaldehyde to form 1,4-butynediol, also known as but-2-yne- 1,4-diol. Hydrogenation of 1,4-butynediol gives 1,4-butanediol. 1,4-BD is also made on a large industrial scale by continuous hydrogenation of the 2-butyne- 1,4-diol over modified nickel catalysts. The one-stage flow process is carried out at 80 - 160 deg C and 300 bar.
Mitsubishi uses a three-step process:
(1) the catalytic reaction of butadiene and acetic acid yields 1,4-diacetoxy-2-butene;
(2) subsequent hydrogenation gives 1,4-diacetoxybutane; and
(3) hydrolysis leads to 1,4-butanediol.

Synthesis Reference(s)

The Journal of Organic Chemistry, 36, p. 2018, 1971 DOI: 10.1021/jo00813a043
Tetrahedron Letters, 33, p. 6371, 1992 DOI: 10.1016/S0040-4039(00)60976-0

Allgemeine Beschreibung

Odorless colorless liquid or solid (depending upon temperature).

Air & Water Reaktionen

Highly flammable. 1,4-Butanediol is hygroscopic. Water soluble.

Reaktivität anzeigen

1,4-Butanediol is heat and light sensitive. 1,4-Butanediol reacts with acid chlorides, acid anhydrides and chloroformates; reacts with oxidizing agents and reducing agents. 1,4-Butanediol is incompatible with isocyanates and acids; also incompatible with peroxides, perchloric acid, sulfuric acid, hypochlorous acid, nitric acid, caustics, acetaldehyde, nitrogen peroxide and chlorine.

Hazard

Toxic by ingestion.

Health Hazard

The acute toxic effects are mild. 1,4-Butanediolis less toxic than its unsaturate analogs,butenediol and the butynediol. The oralLD50 value in white rats and guinea pigsis ~2 mL/kg. The toxic symptoms fromingestion may include excitement, depressionof the central nervous system, nausea, anddrowsiness.

Health Hazard

Ingestion of large amounts needed to produce any symptoms.

Brandgefahr

Nonflammable liquid, flash point (open cup) 121°C.

Sicherheitsprofil

A human poison by an unspecified route. Moderately toxic byingestion and intraperitoneal routes. Human systemic effects: altered sleep time. Combustible when exposed to heat or flame. To fight fire, use alcohol foam, mist, foam, CO2, dry chemical. Incompatible with oxidizing materials. When heated to decomposition it emits acrid smoke and fumes.

läuterung methode

Distil the glycol and store it over Linde type 4A molecular sieves, or crystallise it twice from anhydrous diethyl ether/acetone, and redistil it. It has been recrystallised from the melt and doubly distilled in vacuo in the presence of Na2SO4. [Beilstein 1 IV 2515.]

Butan-1,4-diol Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Butan-1,4-diol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 485)Lieferanten
Firmenname Telefon Fax E-Mail Land Produktkatalog Edge Rate
Zibo Dorne Chemical Technology co. LTD
13583358881 +8613583358881
Ethan@dornechem.com CHINA 104 58
Hebei Lihe Biotechnology Co.,ltd
13315122300 86-311-80292533
sales@lihebiotech.com CHINA 309 58
XINGTAI XINGJIU NEW MATERIAL TECHNOLOGY CO., LTD
+8617731987558
xingjiu@xingjiubiotech.com China 997 58
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418679
86-0551-65418697 info@tnjchem.com China 3000 55
Chongqing Chemdad Co., Ltd
+86-13650506873
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Shanxi Naipu Import and Export Co.,Ltd
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Qingdao kaimoshi biochemical technology co., ltd.
+(86) 571 87700752
+(86) 571 87700752 info@kaimosi.com CHINA 145 58
Wuhan Monad Medicine Tech Co.,LTD
18771942761 02768782018
sales01@whmonad.com CHINA 1000 58
Weijer International Trade (Hebei) Co., Ltd.
18131113408
Bruce@weijier.cn CHINA 82 58
Hebei Senko Biotechnology Co., Ltd.
0086-133 3137 7233
christina@senko-bio.com CHINA 289 58

110-63-4(Butan-1,4-diol)Verwandte Suche:


  • 1,4-BUTYLENE GLYCOL
  • 1,4-BUTANEDIOL
  • 1,4-DIHYDROXYBUTANE
  • AKOS BBS-00004303
  • BDO
  • BUTANEDIOL, 1,4-
  • TETRAMETHYLENE GLYCOL
  • VERSALINK CURATIVE 1,4 BDO
  • BUTANE-1,4-DIOL
  • agrisynthb1d
  • butane,1,4-dihydroxy-
  • Butanediol
  • Butylene glycol
  • Dabco BDO
  • Diol 14B
  • diol14b
  • Sucol B
  • 1,4-BD
  • 1,4-Tetramethylene
  • 1,4-Tetramethylene glycol
  • 1,4-tetramethyleneglycol
  • 1,4-Butanediol,1,4-Butylene glycol, Tetramethylene glycol
  • 1,4-Butanediol, 99+% 1LT
  • 1,4-Butanediol, 99+% 2.5LT
  • 1,4-Butylene Glycol 1,4-Dihydroxybutane Tetramethylene Glycol
  • 1,4-Butanediol, water ≤500 ppM
  • 1,4-BUTANEDIOL FOR SYNTHESIS
  • 1,4-Butylene glycol (BDO)
  • 1,4-Butanediol ReagentPlus(R), 99%
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  • 1,4-Butylene glycol~Tetramethylene
  • 4-Butanediol
  • 1,4-Butanediol, 99%, water ≤500 ppm
  • sucolb
  • Tetramethylene 1,4-diol
  • tetramethylene1,4-diol
  • 1,4-dilhydroxybutane
  • 1,4-BUTANEDIOL AR
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  • 1,4-Butylene glycol~Tetramethylene glycol
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  • 1 4-BUTANEDIOL REAGENTPLUS 99%
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  • 1,4-BUTANEDIOL (1,4-BG)
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  • BUTANEDIOL, 1,4-(SG)
  • 1,4-Butandiol
  • 1,4-Butanediol (BDO)
  • 1,4-Butanediol liquid
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