Endothelin-1 (human, porcine)
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- CAS-Nr.
- 117399-94-7
- Englisch Name:
- Endothelin-1 (human, porcine)
- Synonyma:
- Endothelin;ET-1;ENDOTHELIN 1;ET-1, HUMAN;Endothelin 1【pig】;Endotherin 1【rat】;ENDOTHELIN-1(HUMAN);Endotherin 1【mouse】;ET-1, HUMAN, PORCINE;Endothelin 1【canine】
- CBNumber:
- CB4706533
- Summenformel:
- C109H159N25O32S5
- Molgewicht:
- 2491.9
- MOL-Datei:
- 117399-94-7.mol
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Endothelin-1 (human, porcine) Eigenschaften
- Siedepunkt:
- 2467.3±65.0 °C(Predicted)
- Dichte
- 1.273±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
- Löslichkeit
- 1% acetic acid: >1 mg/mL
- Aggregatzustand
- powder
- Farbe
- white
- Wasserlöslichkeit
- Soluble in water.
- Merck
- 13,3610
- InChIKey
- ZUBDGKVDJUIMQQ-UHFFFAOYSA-N
Sicherheit
| WGK Germany |
3 |
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| RTECS-Nr. |
KE9446500 |
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| F |
3-10 |
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| HS Code |
2937190000 |
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Endothelin-1 (human, porcine) Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Endothelin-1 (human, porcine) has been used for coating wells in polystyrene ELISA plates. Potent agonist for ETA and ETB endothelia receptors. Induces the production of hypoxia-inducible factor 1α, and, thus, the production of VEGF.
Biologische Funktion
Endothelins are a family of vasoactive peptides secreted
by endothelial cells. The three major endothelin
peptides are all composed of 21 amino acids. Endothelins
are the most potent vasoconstrictors known.
Contraction of vascular smooth muscle in response to
endothelin is associated with an increase in intracellular
calcium. Increases in endothelin levels have been reported
in patients with vasospastic, hypoxic, and ischemic
diseases.The two identified isoforms of endothelin
receptors have differing affinity for the three endothelin
peptides. Selective and nonselective endothelin receptor
antagonists are in development for potential use
in the treatment of hypertension and other disorders associated
with increased vascular resistance.
Biochem/physiol Actions
Potent agonist for ETA and ETB endothelin receptors. Induces the production of hypoxia-inducible factor 1α, and, thus, the production of VEGF.
Endothelin-1 (human, porcine) Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Endothelin-1 (human, porcine) Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 169)Lieferanten
117399-94-7()Verwandte Suche:
- ET-1, HUMAN
- ET-1, HUMAN AND PORCINE
- ET-1 (HUMAN, BOVINE, DOG, MOUSE, PORCINE, RAT)
- ET-1 (HUMAN, MOUSE, RAT, PIG, BOVINE, DOG)
- ET-1, HUMAN, PORCINE
- ET-1 (HUMAN, PORCINE, DOG, RAT)
- ENDOTHELIN-I, HUMAN, PORCINE
- ENDOTHELIN 1, DOG, HUMAN, PORCINE, RAT
- ENDOTHELIN-1(HUMAN)
- ENDOTHELIN 1, HUMAN AND PORCINE
- ENDOTHELIN-1 (HUMAN, BOVINE, DOG, MOUSE, PORCINE, RAT)
- ENDOTHELIN-1 (HUMAN, MOUSE, RAT, PIG, BOVINE, DOG)
- ENDOTHELIN 1 HUMAN, PORCINE
- ENDOTHELIN-1 (HUMAN) (PORCINE, CANINE, RAT, MOUSE, BOVINE)
- ENDOTHELIN-1 (HUMAN, PORCINE, DOG, RAT)
- ENDOTHELIN-1 HUMAN, PORCINE, RAT, CANINE, MURINE
- CYS-SER-CYS-SER-SER-LEU-MET-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP
- CYS-SER-CYS-SER-SER-LEU-MET-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP HUMAN, PORCINE, RAT, CANINE, MURINE
- CSCSSLMDKECVYFCHLDIIW
- CSCSSLMDKECVYFCHLDIIW (DISULFIDE BRIDGE: 1-15 AND 3-11)
- H-CYS-SER-CYS-SER-SER-LEU-MET-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH
- H-CYS-SER-CYS-SER-SER-LEU-MET-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH (DISULFIDE BRIDGE: 1-15 AND 3-11)
- H-CYS-SER-CYS-SER-SER-LEU-MET-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH, (DISULFIDE BONDS BETWEEN CYS1 AND CYS15/CYS3 AND CYS11)
- M.W. 2491.90 C109H159N25O32S5
- Endothelin 1【canine】
- Endothelin 1【pig】
- Endotherin 1【mouse】
- Endotherin 1【rat】
- CYS-SER-CYS-SER-SER-LEU-MET-ASP-LYS-GLU-CYS-VAL-TYR- PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP(DISULFIDE BRIDGE:CYS1-CYS15, CYS3-CYS11)
- ENDOTHELIN-1 ACETATE
- Endothelin-1 (huMan, bovine, dog, Mouse, porcine, rat)
ET-1 (huMan, bovine, dog, Mouse, porcine, rat)
- Cys-Ser-Cys-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp (Disulfide bridges Cys1-Cys15 and Cys3-Cys11)
- H-Cys-Ser-Cys-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp-OH acetate salt (Disulfide bonds between Cys1 and Cys15/Cys3 and Cys11)
- Endothelin 1 (swine, human)
- ENDOTHELIN 1, HUMAN, PORCINE, 50 UG*
- Endothelin 1, Human and Porcine - CAS 117399-94-7 - Calbiochem
- Endothelin 1, ≥97.0%(HPLC)
- Endothelin 1 (swine)
- ENDOTHELIN 1 HUMAN, PORCINE USP/EP/BP
- High purity CAS 117399-94-7 ENDOTHELIN 1 HUMAN, PORCINE
- Endothelin 1 (swine, human) acetate
- human) acetate(117399-94-7 free base)
- ET-1
- ENDOTHELIN 1
- Endothelin
- (3S,6S,9S,12S,15S,18S)-3-((1H-Imidazol-4-yl)methyl)-18-((1H-indol-3-yl)methyl)-1-((1R,4S,7S,10S,13S,16S,19S,22S,25R,28S,31R,36R,39R,42S,45S)-31-amino-7-(4-aminobutyl)-39-benzyl-4-(2-carboxyethyl)-10-(carboxymethyl)-42-(4-hydroxybenzyl)-19,22,28-tris(hydroxymethyl)-16-isobutyl-45-isopropyl-13-(2-(methylthio)ethyl)-3,6,9,12,15,18,21,24,27,30,38,41,44,47-tetradecaoxo-33,34,49,50-tetrathia-2,5,8,11,14,17,20,23,26,29,37,40,43,46-tetradecaazabicyclo[23.22.4]henpentacontan-36-yl)-12,15-di((S)-sec-butyl
- EDN1 Acitive Peptide
- Mouse Anti-ET-1(2C4) antibody
- Rabbit Anti-ET-1 antibody
- Rabbit Anti-Big endothelin-1 antibody
- Endothelin 1，acetate salt
- 117399-94-7
- C109H159O32N25S5
- C109H159N25O32S5
- 多肽抗原
- Cell Signaling Enzymes
- Biochemicals and Reagents
- Application Index
