Mannitol

Mannitol Struktur
87-78-5
CAS-Nr.
87-78-5
Bezeichnung:
Mannitol
Englisch Name:
Mannitol
Synonyma:
MANNITOL BP;MANNITOL USP;Maitol;DL-Mannitol;Hexahydroxyhexane;Cordycepin 10% Mannitol;NSC 9256;MANNITOL;MANNITOL B;Mannidex 16700
CBNumber:
CB4720971
Summenformel:
C6H14O6
Molgewicht:
182.17
MOL-Datei:
87-78-5.mol

Mannitol Eigenschaften

Schmelzpunkt:
167°C
Siedepunkt:
494.9°C
Dichte
1.596
Brechungsindex
1.5970 (estimate)
storage temp. 
Inert atmosphere,Room Temperature
pka
pKa 13.50(H2O,t =18)(Approximate)
Wasserlöslichkeit
177.3g/L(25 ºC)
Dielectric constant
3.0(22℃)
InChI
InChI=1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4-,5-,6-/m1/s1
InChIKey
FBPFZTCFMRRESA-KVTDHHQDSA-N
SMILES
OC[C@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O
CAS Datenbank
87-78-5(CAS DataBase Reference)
EPA chemische Informationen
Mannitol (87-78-5)

Sicherheit

HS Code  29054300

Mannitol Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

It can be used to lower intraocular pressure and in the postoperational period in ophthalomological procedures as well as during brain edema.

Chemische Eigenschaften

D-mannitol (D-mannohexan-1.2.3.4.5.6-hexaol) is a constituent of several plants including the Manna ash, several edible plants, and seaweed. Parts of the latter contain up to 10 % mannitol by weight. The solubility in water is approximately 230 g/L at room temperature and it increases with increasing temperature. Mannitol is stable under the common processing conditions of foods.
Mannitol is approximately 50 % as sweet as sucrose and non-cariogenic. In the European Union, maltitol is approved as E 421 for a large number of food applications. In the United States, mannitol produced by hydrogenation of glucose or fructose solutions or by fermentation by Zygosaccharomyces rouxii or Lactobacillus intermedius is approved for several food applications. It is also approved in many other countries.

Verwenden

Mannitol is a polyol (polyhydric alcohol) produced from hydrogena- tion from fructose that functions as a sweetener, humectant, and bulking agent. it has low hygroscopicity and poor oil solvency. it has 1.6 kcal/g. it is approximately 22% soluble in water and is approximately 72% as sweet as sugar, exhibiting a cool, sweet taste. it functions as a dusting agent with starch in chewing gum. it is used in sugarless candy, chewing gum, cereal, and pressed mints.

Definition

mannitol: A polyhydric alcohol,CH2OH(CHOH)4CH2OH, derived frommannose or fructose. It is the mainsoluble sugar in fungi and an importantcarbohydrate reserve in brownalgae. Mannitol is used as a sweetenerin certain foodstuffs and as a diureticto relieve fluid retention.

Mechanism of action

Today, mannitol is the most widely used osmotic diuretic. It raises osmotic pressure in renal tubules, thus reducing reabsorption of water in the nephrons. As a result, a large quantity of free water is released, sodium secretion increases, and as a rule, an insignificant amount of potassium is secreted. Mannitol is used as an adjuvant drug for preventing oliguria and anuriua.

Clinical Use

Mannitol is the agent most commonly used as an osmotic diuretic. Sorbitol also can be used for similar reasons.Mannitol is administered intravenously in solutions of 5 to 50% at a rate of administration that is adjusted to maintain the urinary output at 30 to 50 ml/hour. Mannitol is filtered at the glomerulus and is poorly reabsorbed by the kidney tubule. The osmotic effect of mannitol in the tubule inhibits the reabsorption of water, and the rate of urine flow can be maintained. It also is used to reduce intracranial pressure by reducing cerebral intravascular volume.

Sicherheitsprofil

A poison by intravenous route. Human systemic effects. When heated to decomposition it emits acrid smoke and irritating vapors.

Mannitol Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Mannitol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 400)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Hebei Guanlang Biotechnology Co,.LTD
+8619930503252
daisy@crovellbio.com China 5964 58
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418671
sales@tnjchem.com China 34572 58
Wuhan Topule Biopharmaceutical Co., Ltd
+8618327326525
masar@topule.com China 8474 58
Hebei Jingbo New Material Technology Co., Ltd
+8619931165850
hbjbtech@163.com China 1000 58
Nanjing Deda New Material Technology Co., Ltd
+8613223293093
bella@njdeda.com China 81 58
Shaanxi TNJONE Pharmaceutical Co., Ltd
+8618740459177
sarah@tnjone.com China 893 58
Sinoway Industrial co., ltd.
0592-5800732; +8613806035118
xie@china-sinoway.com China 992 58
Henan Bao Enluo International TradeCo.,LTD
+86-17331933971 +86-17331933971
deasea125996@gmail.com China 2503 58
Ouhuang Engineering Materials (Hubei) Co., Ltd
+8617702722807
admin@hbouhuang.com China 2259 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
info@tianfuchem.com China 21691 55

87-78-5(Mannitol)Verwandte Suche:


  • MANNITOL
  • MANNITOL USP/BP
  • MANNITOL PYROGEN FREE USP24
  • MANNITOL PYROGEN FREE USP.
  • MANNITOL B
  • MANNITOL USP 24
  • N.F,USP MANNITOL
  • MANNITOL, CP2000/BP2000/USP23
  • Mannidex 16700
  • Mannitol (8CI, 9CI)
  • NSC 9256
  • Mannitol###D-Mannitol
  • D-glycero-Hexitol
  • Mannitol, 98%, from Phaeophyta
  • mannitol crystalline powder
  • Mannitol crystals
  • Mannitol/Mannitol powder
  • Mannitol USP/EP/BP
  • Mannitol CAS 87 78 5
  • D-Mannitol Powder CAS?87-78-5?Pharmaceutical Grade Mannitol Powder
  • Mannitol(87-78-5)
  • Maitol
  • DL-Mannitol
  • Hexahydroxyhexane
  • Cordycepin 10% Mannitol
  • MANNITOL USP
  • MANNITOL BP
  • rel-(2R,3R,4R,5R)-Hexane-1,2,3,4,5,6-hexaol
  • Cocaine Hydrochloride Impurity 1(Cocaine Hydrochloride EP Impurity A )
  • 87-78-5
  • 87-78-5
  • Elisa Kit-plant ELISA Kit
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