4-[(Dichloracetyl)methylamino]phenyl-2-furoat
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- CAS-Nr.
- 3736-81-0
- Bezeichnung:
- 4-[(Dichloracetyl)methylamino]phenyl-2-furoat
- Englisch Name:
- Diloxanide furoate
- Synonyma:
- 8073cb;Furoate;furamide;amebiazol;furentomin;histomibal;diclofurazol;dichlofurazol;entamidefuroate;diloxanidfuroate
- CBNumber:
- CB4723149
- Summenformel:
- C14H11Cl2NO4
- Molgewicht:
- 328.15
- MOL-Datei:
- 3736-81-0.mol
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4-[(Dichloracetyl)methylamino]phenyl-2-furoat Eigenschaften
- Schmelzpunkt:
- 111-114 °C
- Siedepunkt:
- 438.4±45.0 °C(Predicted)
- Dichte
- 1.424±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- Löslichkeit
- Chloroform (Slightly), Methanol (Slightly)
- Aggregatzustand
- Solid
- pka
- -0?+-.0.50(Predicted)
- Farbe
- Off-White to Light Beige
- BCS Class
- 4
- CAS Datenbank
- 3736-81-0(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Kennzeichnung gefährlicher |
Xn |
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| R-Sätze: |
22 |
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| S-Sätze: |
36 |
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| WGK Germany |
3 |
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| RTECS-Nr. |
LV1821800 |
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| HS Code |
2924296000 |
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| Toxizität |
mouse,LDLo,oral,710mg/kg (710mg/kg),Archives of Environmental Contamination and Toxicology. Vol. 14, Pg. 111, 1985. |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitsschädlich bei Verschlucken. |
Akute Toxizität oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
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| Sicherheit |
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4-[(Dichloracetyl)methylamino]phenyl-2-furoat Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R22:Gesundheitsschädlich beim Verschlucken.
S-Sätze Betriebsanweisung:
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Verwenden
selective agonist for delta-opioid receptor
Indications
Diloxanide furoate (Furamide) is an amebicide that is
effective against trophozoites in the intestinal tract. In
mild or asymptomatic infections, cures of 83 to 95%
have been achieved; in patients with dysentery, cure
rates may be less impressive. The drug is administered
only orally and is rapidly absorbed from the gastrointestinal
tract following hydrolysis of the ester group. It
is remarkably free of side effects, but occasionally flatulence,
abdominal distention, anorexia, nausea, vomiting,
diarrhea, pruritus, and urticaria occur. Diloxanide is excreted
in the urine, largely as the glucuronide. It is not
available in the United States.
Clinical Use
Diloxanide furoate (available from the Centers for Disease Control and Prevention [CDC]) is
prescribed for the treatment of asymptomatic amebiasis but is ineffective as a single agent for the
extraintestinal form of the disease. The drug is
administered orally and is hydrolyzed in the gut to give diloxanide, which is considered to be the
active drug. Diloxanide is the only form identified in the bloodstream. The drug is found in the
urine as the glucuronide.
4-[(Dichloracetyl)methylamino]phenyl-2-furoat Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
4-[(Dichloracetyl)methylamino]phenyl-2-furoat Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 92)Lieferanten
3736-81-0(4-[(Dichloracetyl)methylamino]phenyl-2-furoat)Verwandte Suche:
- 2,2-DICHLORO-N-(4-HYDROXYPHENYL)-N-METHYLACETAMIDE 2-FUROIC ACID ESTER
- DILOXANIDE FUROATE
- 2-furancarboxylicacid,4-((dichloroacetyl)methylamino)phenylester
- 2-furoicacid,esterwith2,2-dichloro-4’-hydroxy-n-methylacetanilide
- 8073cb
- amebiazol
- dichlofurazol
- diclofurazol
- diloxanidfuroate
- entamide2-furoate
- entamidefuroate
- furamide
- furamide(amebicide)
- furentomin
- histomibal
- 4-[(dichloroacetyl)methylamino]phenyl 2-furoate
- Diloxanide 2-furoic acid ester
- [4-[(2,2-dichloroacetyl)-methylamino]phenyl] furan-2-carboxylate
- [4-[2,2-dichloroethanoyl(methyl)amino]phenyl] furan-2-carboxylate
- furan-2-carboxylic acid [4-[(2,2-dichloroacetyl)-methyl-amino]phenyl] ester
- Diloxanide Furoate (200 mg)
- 4-(2,2-Dichloro-N-MethylacetaMido)phenyl furan-2-carboxylate
- Furoate
- 2-Furancarboxylic acid, 4-[(2,2-dichloroacetyl)methylamino]phenyl ester
- Diloxanide Furoate (1204805)
- 3736-81-0
- 376-81-0
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