Dehydrogenase, Lipoamid-
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- CAS-Nr.
- 9001-18-7
- Bezeichnung:
- Dehydrogenase, Lipoamid-
- Englisch Name:
- DIAPHORASE
- Synonyma:
- QR1;DTD;DIA4;DHQU;NQO1;NMOR1;232-587-6;EC 1.6.99;DTD HUMAN;Diaphorse
- CBNumber:
- CB4742128
- Summenformel:
- Molgewicht:
- 0
- MOL-Datei:
- Mol file
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Dehydrogenase, Lipoamid- Eigenschaften
Dehydrogenase, Lipoamid- Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Verwenden
Diaphorase from Clostridium kluyveri, or Lipoyl dehydrogenase, has been used in a study to assess the protein-protein interactions in assembly of lipoic acid on the 2-oxoacid dehydrogenases of aerobic metabolism. Lipoyl dehydrogenase has also been used in a study to investigate the redox regulation of tyrosine nitration and 3-nitrotyrosine reduction by antioxidants.
Biochem/physiol Actions
Diaphorase catalyzes the oxidation of either β-NADH or β-NADPH in the presence of an electron acceptor such as methylene blue or 2,6-dichlorophenolindophenol. Diaphorases which are specific for either β-NADH or β-NADPH are known. The pig heart enzyme of Straub seems to have native diaphorase (β-NADH specific) as well as lipoic and lipoamide dehydrogenase activities. It is reported to be a single protein. However, Massey reports that diaphorase is probably a denatured lipoamide dehydrogenase. Pre-incubation of the pig heart preparation with Cu2+ reduces the lipoamide dehydrogenase activity and proportionately increases the β-NADH diaphorase activity. In our laboratory, we have demonstrated this copper effect to some degree on the pig heart enzyme, but no appreciable effect was observed on the Clostridium kluyveri or torula yeast preparations. The lipoamide dehydrogenase:diaphorase ratio is a measure of the denaturation.
Dehydrogenase, Lipoamid- Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Dehydrogenase, Lipoamid- Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 99)Lieferanten
9001-18-7(Dehydrogenase, Lipoamid-)Verwandte Suche:
- NQO1
- DHQU
- DIA4
- Monoclonal Anti-NQO1 antibody produced in mouse
- NMOR1
- QR1
- E.C. 1.6.4.3
- Lipoamide dehydrogenase (NADH)
- Lipoamide oxidoreductase
- Lipoamide reductase
- Lipoate dehydrogenase
- Lipoic acid dehydrogenase
- alpha-Lipoamide dehydrogenase
- Dihydrolipoamide dehydrogenase
- lipoamide dehydrogenase from bovine intestinal mucosa
- lipoamide dehydrogenase from porcine heart
- DIAPHORASE, FROM CLOSTRIDIUM KLUYVERI, TYPE III
- DIAPHORASE etrapure
- NAD(P)H dehydrogenase (quinone), NAD(P)H: (quinone-acceptor) oxidoreductase
- 232-587-6
- Dihydrolipoate dehydrogenase
- Dihydrolipoic dehydrogenase
- Dihydrolipoyl dehydrogenase
- Dihydrothioctic dehydrogenase
- QUINONE REDUCTASE HUMAN
- QUINONE REDUCTASE
- NADH: LIPOAMIDE OXIDOREDUCTASE TYPE III
- NADH: LIPOAMIDE OXIDOREDUCTASE
- NADH: DYE OXIDOREDUCTASE
- NAD(P)H: ACCEPTOR OXIDOREDUCTASE
- IUB: 1.6.99.1
- EC 1.6.99.2
- EC 1.6.99
- EC: 1.6.99
- EC 1.8.1.4 TYPE III
- EC 1.8.1.4
- DT DIAPHORASE HUMAN
- DT DIAPHORASE
- DTD HUMAN
- DTD
- DIHYDROLIPOAMIDE: NAD OXIDOREDUCTASE
- DIHYDROLIPOAMIDE: NAD+ OXIDOREDUCTASE
- LIPOAMIDE DEHYDROGENASE TYPE III
- LIPOAMIDE DEHYDROGENASE
- LIPOYL DEHYDROGENASE
- Dehydrogenase, lipoamide
- LIPOAMIDE DEHYDROGENASE TYPE III FROM PO
- LIPOAMIDE DEHYDROGENASE TYPE V FROM TORU LA YEAST
- LIPOAMIDE DEHYDROGENASE FROM BOVINE INTE
- DIAPHORASE FROM CLOSTRIDIUM KLUYVERI
- DiaphoraseExClostridiumKluyveri
- DIAPHORASE
- Diaphorase from Clostridium kluyveri, ≥25 units/mg dry weight
- Native Clostridium kluyveri Diaphorase
- Diaphorase 22 from Recombinant E.coli
- DIAPHORASE USP/EP/BP
- Diaphorase from E. coli, Recombinant
- Diaphorase ex. Clostridium Sp., 30U/mg
