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ChemicalBook > Produktkatalog >Aktive pharmazeutische Wirkstoffe (APIs) >Vitamine und Mineralien >Vitamin C Ergänzungen >Folsure

Folsure Produkt Beschreibung

CAS-Nr.59-30-3
Bezeichnung:Folsure
Englisch Name:Folic acid
Synonyma:
PGA;Folan;folic;Aspol;FOLSAN;Folate;Folbal;Folsav;VM/PGA;PTEGLU
CBNumber:CB5100903
Summenformel:C19H19N7O6
Molgewicht:441.4
MOL-Datei:59-30-3.mol
Folsure physikalisch-chemischer Eigenschaften
Schmelzpunkt:: 250 °C
alpha : 20 º (c=1, 0.1N NaOH)
Siedepunkt:: 552.35°C (rough estimate)
Dichte: 1.4704 (rough estimate)
Brechungsindex: 1.6800 (estimate)
storage temp. : 2-8°C
Löslichkeit: boiling water: soluble1%
Aggregatzustand: Crystalline Powder
pka: pKa 2.5 (Uncertain)
Farbe: Yellow to orange
Wasserlöslichkeit: 1.6 mg/L (25 ºC)
Merck : 14,4221
BRN : 100781
Stabilität:: Stable. Incompatible with heavy metal ions, strong oxidizing agents, strong reducing agents. Solutions may be light and heat sensitive.
InChIKey: OVBPIULPVIDEAO-LBPRGKRZSA-N
CAS Datenbank: 59-30-3(CAS DataBase Reference)
NIST chemische Informationen: Folic acid(59-30-3)
EPA chemische Informationen: L-Glutamic acid, N-[4-[[(2-amino-1,4-dihydro- 4-oxo-6-pteridinyl)methyl] amino]benzoyl]-(59-30-3)
Sicherheit
R-Sätze:: 33-62-68
S-Sätze:: 24/25
WGK Germany : 1
RTECS-Nr.: LP5425000
F : 8
TSCA : Yes
HS Code : 29362900
Giftige Stoffe Daten: 59-30-3(Hazardous Substances Data)

Folsure Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R33:Gefahr kumulativer Wirkungen.
R62:Kann möglicherweise die Fortpflanzungsfähigkeit beeinträchtigen.
R68:Irreversibler Schaden möglich.
S-Sätze Betriebsanweisung:
S24/25:Berührung mit den Augen und der Haut vermeiden.
Chemische Eigenschaften
orange to yellow crystalline powder
Verwenden
A vitamin needed to synthesize DNA, conduct DNA repair and methylate DNA, it also acts as a cofactor in biological reactions involving folate.
Verwenden
hematopoietic vitamin
Verwenden
folic acid is generally used as an emollient. In vitro and in vivo skin studies now indicate its capacity to aid in DnA synthesis and repair, promote cellular turnover, reduce wrinkles, and promote skin firmness. There is some indication that folic acid may also protect DnA from uV-induced damage. Folic acid is a member of the vitamin B complex and is naturally occurring in leafy greens.
Verwenden
Literature tends to indicate that B vitamins cannot pass through the layers of the skin and, therefore, are of no value in the skin surface. Current experiments demonstrate, however, that vitamin B2 acts as a chemical reaction accelerator, enhancing the performance of tyrosine derivatives in suntan-accelerating preparations.
Verwenden
Folic Acid is a water-soluble b-complex vitamin that aids in the for- mation of red blood cells, prevents certain anemias, and is essential in normal metabolism. high-temperature processing affects its sta- bility. it is best stored at lower than room temperatures. it is also termed folacin. it is found in liver, nuts, and green vegetables.
Definition
ChEBI: An N-acyl-amino acid that is a form of the water-soluble vitamin B9. Its biologically active forms (tetrahydrofolate and others) are essential for nucleotide biosynthesis and homocysteine remethylation.
Allgemeine Beschreibung
Odorless orange-yellow needles or platelets. Darkens and chars from approximately 482°F.
Air & Water Reaktionen
Insoluble in water. Aqueous solutions have pHs of 4.0-4.8.
Reaktivität anzeigen
Acid solutions of Folic acid are sensitive to heat, but towards neutrality, stability progressively increases. Solutions are inactivated by ultraviolet light and alkaline solutions are sensitive to oxidation. Folic acid is also inactivated by light. Folic acid is incompatible with oxidizing agents, reducing agents and heavy metal ions.
Brandgefahr
Flash point data for Folic acid are not available; however, Folic acid is probably combustible.
Sicherheitsprofil
Poison by intraperitoneal and intravenous routes. Experimental teratogenic effects. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
läuterung methode
If paper chromatography indicates impurities, then recrystallise it from hot H2O or from dilute acid [Walker et al. J Am Chem Soc 70 19 1948]. Impurities may be removed by repeated extraction with n-BuOH of a neutral aqueous solution of folic acid (by suspending in H2O and adding N NaOH dropwise till the solid dissolves, then adjusting the pH to ~7.0-7.5) followed by precipitation with acid, filtration, or better collected by centrifugation and recrystallised form hot H2O. [Blakley Biochem J 65 331 1975, Kalifa et al. Helv Chim Acta 6 1 2739 1978.] Chromatography on cellulose followed by filtration through charcoal has also been used to obtain pure acid. [Sakami & Knowles Science 129 274 1959.] UV: max 247 and 296nm ( 12,800 and 18,700) in H2O pH 1.0; 282 and 346nm ( 27.600 and 7,200) in H2O pH 7.0; 256, 284 and 366nm ( 24600, 24,500 and 86,00) in H2O pH 13 [Rabinowitz in The Enzymes (Boyer et al. Eds), 2 185 1960]. [Beilstein 26 III/IV 3944.]
Folsure Upstream-Materialien And Downstream Produkte
Upstream-Materialien
1,1,3-Trichloraceton 4-Phenylazophenylen-1,3-diaminmonohydrochlorid 2,3-Dibrompropionaldehyd 2,5,6-Triaminopyrimidin-4-olsulfat Dinatriumdisulfit
Downstream Produkte
Folsure Anbieter Lieferant Produzent Hersteller Vertrieb Händler.      Global( 491)Lieferanten     
Firmenname Telefon Fax E-Mail Land Produktkatalog Edge Rate
Nanjing Gold Pharmaceutical Technology Co. Ltd.
025-84209270 15906146951
025-84209270wgp@nanjing-pharmaceutical.com CHINA 115 55
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 23982 58
Capot Chemical Co.,Ltd.
+86 (0)571-855 867 18
+86 (0)571-858 647 95sales@capotchem.com China 19919 60
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925Abel@chembj.com CHINA 3203 55
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21914 58
Hebei Jiangkai Trading Co., Ltd
0086-17197824289/17197824028
alice@hbjkai.com CHINA 274 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693info@tianfuchem.com CHINA 20680 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733sales@mainchem.com CHINA 32457 55
Hangzhou FandaChem Co.,Ltd.
0086 158 5814 5714 (Mobile; WhatsApp; Telegram)
+86-571-56059825fandachem@gmail.com CHINA 2672 55
Nanjing Finetech Chemical Co., Ltd.
025-85710122 17714198479
025-85710122sales@fine-chemtech.com CHINA 892 55
 
59-30-3(Folsure)Verwandte Suche:
Cyanocobalamin 2,6-Dimethyloct-7-en-2-ol 3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-ol Riboflavin MULTIVITAMIN Dibenzoylperoxid Pyridoxinhydrochlorid P-AMINOBENZAMIDE GLUTAMIC ACID ASCORBICACID Glutamic acid Hyaluronsure Natrium-N-lauroylsarkosinat Glutaminsure 9,10-Secocholesta-5,7,10(19)-trien-3-ol VitaminBComplex Vitamin A Zitronensure Ascorbinsure
N-[4-[[(2-AMINO-4-HYDROXY-6-PTERIDYL)METHYL]AMINO]BENZOYL]GLUTAMIC ACID n-4-[(2-amido-4-oxo-1,4-dihydro-6-terene)methylamino]benzoyl-l-glutamic acid VITIMIN M VITAMIN BC Vitamin B11 VITAMIN M ACIDUM FOLICUM INCAFOLIC FOLSAN FOLSAURE FOLIC ACID FOLIC ACID HYDRATE FOLACIN CYTOFOL l-pteroylglutamic acid 2-amino-6-((p-((1,3-dicarboxypropyl)carbamoyl)anilino)methyl)-4-pteridino 4-Pteridinol, 2-amino-6-((p-((1,3-dicarboxypropyl)carbamoyl)anilino)methyl)- acfol(spain) Acifolic antianemiafactor component of Mission prenatal component of Plastulen-n factoru Folacid folaemin(netherlands) Folan folasic(australia) Folate Folbal Folcidin Folcysteine Foldine foldine(france) Folettes Foliamin folic folicacid(vitaminb11) Folicet folico(italy) folina(italy) Folipac Folsav Foluite Folvite Glutamic acid, N-(p-(((2-amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)- Glutamic acid, N-(p-(((2-amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-, l- Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L Glutamic acid, pteroyl-, l- glutamicacid,n-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amin Kyselina listova kyselinalistova L-Glutamic acid, N-[4-[[(2-amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]- l-glutamicacid,n-(4-(((2-amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)be l-glutamicacid,n-[4-[[(2-amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]be Liver Lactobacillus, casei factor liverlactobacilluscaseifactor Millafol Mission prenatal
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