Isoleucine

Isoleucine Struktur
7004-09-3
CAS-Nr.
7004-09-3
Englisch Name:
Isoleucine
Synonyma:
ISOLEUCINE
CBNumber:
CB52130861
Summenformel:
C6H13NO2
Molgewicht:
131.17
MOL-Datei:
7004-09-3.mol

Isoleucine Eigenschaften

Schmelzpunkt:
>166°C (dec.)
storage temp. 
Refrigerator
Löslichkeit
Aqueous Acid (Slightly), DMSO (Slightly, Sonicated)
Aggregatzustand
Solid
pka
2.32(at 25℃)
Farbe
White to Off-White

Sicherheit

Isoleucine Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Isoleucine ( abbreviated as Ile or I ) is an α - amino acid with the chemical formula HO2CCH(NH2)CH(CH3)CH2CH3. It is an essential amino acid, which means that humans cannot synthesize it, so it must be ingested. Its codons are AUU, AUC and AUA.
With a hydrocarbon side chain, isoleucine is classified as a hydrophobic amino acid. Together with threonine, isoleucine is one of two common amino acids that have a chiral side chain. Four stereoisomers of isoleucine are possible, including two possible diastereomers of L-isoleucine. However, isoleucine present in nature exists in one enantiomeric form, (2S,3S)-2-amino-3-methylpentanoic acid.

Chemische Eigenschaften

Crystals. Slightly soluble in water; nearly insoluble in alcohol; insoluble in ether.

Occurrence

Even though this amino acid is not produced in animals, it is stored in high quantities. Foods that have high amounts of isoleucine include eggs, soy protein, seaweed, turkey, chicken, lamb, cheese, and fish.

Verwenden

Amino acid.

Definition

An essential amino acid, found naturally in the L(+) form.

Biosynthese

As an essential nutrient, it is not synthesized in the body, hence it must be ingested, usually as a component of proteins. In plants and microorganisms, it is synthesized via several steps, starting from pyruvic acid and alpha - keto glutarate. Enzymes involved in this biosynthesis include :
Aceto lactate synthase (also known as aceto hydroxy acid synthase)
Aceto hydroxy acid iso meroreductase
Dihydroxy acid dehydratase
Valine amino transferase.

Stoffwechsel

Isoleucine is both a glucogenic and a ketogenic amino acid. After transamination with alpha-ketoglutarate the carbon skeleton can be converted into either Succinyl CoA, and fed into the TCA cycle for oxidation or converted into oxaloacetate for gluconeogenesis (hence glucogenic). It can also be converted into Acetyl CoA and fed into the TCA cycle by condensing with oxaloacetate to form citrate. In mammals Acetyl CoA cannot be converted back to carbohydrate but can be used in the synthesis of ketone bodies or fatty acids, hence ketogenic.

Isoleucine Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Isoleucine Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 10)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
info@tianfuchem.com China 21691 55
Nanjing Shizhou Biology Technology Co.,Ltd 13675144456
sean.lv@synzest.com China 10787 58

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