Iron Chelator, Dp44mT

152095-12-0

CAS-Nr.: 152095-12-0

Englisch Name:: Iron Chelator, Dp44mT

Synonyma:: de44mt;Dp44mT;CS-2521;Iron Chelator;Iron Chelator, Dp44mT;Di-2-pyridylketone-4,4,-dimethyl-3-thiosemicarbazone;2-(Di-2-pyridinylmethylene)-N,N-dimethyl-hydrazinecarbothioamide;2-(di(pyridin-2-yl)methylene)-N,N-imethylhydrazinecarbothioamide;2-(Di(pyridin-2-yl)methylene)-N,N-dimethylhydrazinecarbothioamide;Hydrazinecarbothioamide, 2-(di-2-pyridinylmethylene)-N,N-dimethyl-

CBNumber:: CB52524488

Summenformel:: C14H15N5S

Molgewicht:: 285.37

MOL-Datei:: 152095-12-0.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 86

Iron Chelator, Dp44mT Eigenschaften

storage temp.: 2-8°C

Löslichkeit: DMSO: ≥5mg/mL

Aggregatzustand: powder

Farbe: yellow to orange

Sensitive: Light Sensitive

Stabilität:: Stable for 1 year from date of purchase as supplied. Solutions in DMSO may ne stored at -20°C for 1 month.

Sicherheit

Risiko- und Sicherheitserklärung
Gefahreninformationscode (GHS)

Kennzeichnung gefährlicher	Xn
R-Sätze:	22
RIDADR	UN 2811 6.1 / PGIII
WGK Germany	3
HazardClass	6.1

Bildanzeige (GHS)

Alarmwort

Achtung

Gefahrenhinweise

Code	Gefahrenhinweise	Gefahrenklasse	Abteilung	Alarmwort	Symbol	P-Code
H301	Giftig bei Verschlucken.	Akute Toxizität oral	Kategorie 3	Achtung	src="/GHS06.jpg" width="20" height="20" />	P264, P270, P301+P310, P321, P330,P405, P501

Sicherheit

P301+P310

BEI VERSCHLUCKEN: Sofort GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen.

Iron Chelator, Dp44mT Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Iron Chelator, Dp44mT is a cell-permeable di-2-pyridyl thiosemicarbazone (DpT) based tridentate ligand.

Biochem/physiol Actions

Dp44mT (di-2-pyridylketone-4,4,-dimethyl-3-thiosemicarbazone) influences lysosome integrity through copper binding. It induces reactive oxygen species (ROS) generation by redox cycling of iron complex. Dp44mT exhibits anti cancer action by attenuating Ndrg-1 (N-myc downstream regulated 1), a metastasis suppressor protein. It also alters the cyclin family of proteins (A, B, D1, D2,D3 and cyclin-dependent kinase 2) known for cell-cycle regulation. Dp44mT is known to promote apoptosis in neuroepithelioma, melanoma and breast cancer.

Iron Chelator, Dp44mT Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Iron Chelator, Dp44mT Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 86)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
career henan chemical co	+86-0371-86658258 15093356674;	factory@coreychem.com	China	29826	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6313	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	13417589054	trendseenbio@gmail.com	China	11681	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43348	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	57511	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131981	58
Shanghai Boyle Chemical Co., Ltd.		sales@boylechem.com	China	2923	55

152095-12-0()Verwandte Suche:

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Iron Chelator, Dp44mT
2-(Di-2-pyridinylmethylene)-N,N-dimethyl-hydrazinecarbothioamide
Di-2-pyridylketone-4,4,-dimethyl-3-thiosemicarbazone
Dp44mT
de44mt
CS-2521
Iron Chelator
Hydrazinecarbothioamide, 2-(di-2-pyridinylmethylene)-N,N-dimethyl-
2-(Di(pyridin-2-yl)methylene)-N,N-dimethylhydrazinecarbothioamide
2-(di(pyridin-2-yl)methylene)-N,N-imethylhydrazinecarbothioamide
152095-12-0