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AG 1295

AG 1295 Struktur
71897-07-9
CAS-Nr.
71897-07-9
Englisch Name:
AG 1295
Synonyma:
AG 1295;NSC 380341;AG 1295 USP/EP/BP;TYRPHOSTIN AG 1295;TYROPHOSTIN AG1295;AG-1295 (NSC 380341;TYRPHOSTIN AG 1295, 99+%;AG 1295 PLATELET-DERIVED GROW;6,7-DIMETHYL-2-PHENYLQUINOXALINE;Quinoxaline, 6,7-dimethyl-2-phenyl-
CBNumber:
CB5683675
Summenformel:
C16H14N2
Molgewicht:
234.3
MOL-Datei:
71897-07-9.mol
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AG 1295 Eigenschaften

Schmelzpunkt:
121 °C
Siedepunkt:
398.3±37.0 °C(Predicted)
Dichte
1.127±0.06 g/cm3(Predicted)
storage temp. 
−20°C
Löslichkeit
Chloroform (Slightly), Ethyl Acetate (Slightly)
Aggregatzustand
White solid
pka
1.29±0.30(Predicted)
Farbe
Yellow

Sicherheit

S-Sätze: 22-24/25
WGK Germany  3

AG 1295 Chemische Eigenschaften,Einsatz,Produktion Methoden

S-Sätze Betriebsanweisung:

S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.

Beschreibung

Protein tyrosine kinase (PTK) inhibitors are potential antiproliferative agents for diseases caused by the hyperactivity of PTKs. Tyrphostins are a class of antiproliferative compounds which act as PTK blockers. PTK inhibitors specific for platelet-derived growth factor (PDGF) receptor kinase could help in the treatment of atherosclerosis, restenosis, pulmonary fibrosis, and gliomas. AG-1295 is a quinoxaline-type tyrphostin that acts as a potent and selective inhibitor of PDGF receptor kinase in vitro and in Swiss 3T3 cells (IC50s range from 0.3-1 μM). It inhibits PDGF-stimulated DNA synthesis with an IC50 value of 2.5 μM without affecting activity of the EGF receptor.

Verwenden

AG-1295 is a protein tyrosine kinase inhibitor. Antiproliferative agent used in the treatment of atherosclerosis, pulmonary fibrosis, and gliomas.

AG 1295 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

AG 1295 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 71)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
career henan chemical co 		+86-0371-86658258
sales@coreychem.com China 29914 58
Hubei xin bonus chemical co. LTD 		86-13657291602
linda@hubeijusheng.com CHINA 22968 58
Chongqing Chemdad Co., Ltd 		+86-023-61398051 +8613650506873
 sales@chemdad.com China 39916 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 19892 58
Dideu Industries Group Limited 		+86-29-89586680 +86-15129568250
 1026@dideu.com China 29322 58
Aladdin Scientific 		+1-833-552-7181
sales@aladdinsci.com United States 52927 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788
 jkinfo@jkchemical.com China 96815 76
Spectrum Chemical Manufacturing Corp. 021-021-021-67601398-809-809-809 15221380277
 marketing_china@spectrumchemical.com China 9664 60
Struchem Co., Ltd. 0512-0512-63009836 15365350169
 helen@struchem.com China 3989 60
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
 info@efebio.com China 9709 58

71897-07-9()Verwandte Suche:

Vinpocetin Zaprinast Rolipram
  • 6,7-DIMETHYL-2-PHENYLQUINOXALINE
  • AG 1295
  • TYROPHOSTIN AG1295
  • TYRPHOSTIN AG 1295
  • AG 1295 PLATELET-DERIVED GROW
  • TYRPHOSTIN AG 1295, 99+%
  • Quinoxaline, 6,7-dimethyl-2-phenyl-
  • AG-1295 (NSC 380341
  • NSC 380341
  • AG 1295 USP/EP/BP
  • Platelet-derived growth factor receptor,RTK,AG 1295,inhibit,PDGF-receptor,AG-1295,autophosphorylation,Inhibitor,AG1295,PDGFR
  • 71897-07-9
  • 70897-07-9
  • Cell Signaling and Neuroscience
  • Cell Biology
  • BioChemical
  • Kinase/Phosphatase Biology
  • Receptor Tyrosine Kinase Inhibitors
  • Platelet Derived Growth Factor Receptor (PDGFR)
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