tert-Butyl diethylphosphonoacetate
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- CAS-Nr.
- 27784-76-5
- Englisch Name:
- tert-Butyl diethylphosphonoacetate
- Synonyma:
- tert-butyl 2-(diethoxyphosphoryl)acetate;tert-Butyl diethylph;DIETHYL (BOC-METHYL)PHOSPHONATE;T-BUTYL DIETHYL PHOSPHONOACETATE;Tert-buty diethylphosphonoacetate;tert-Butyl diethylphosponoacetate;Tert-butyl diethylphosphonoactate;TERT-BUTYL DIETHYLPHOSPHONOACETATE;Tert-butyl diehylphosphonoacetate;Tert-butyl diethyl phosphonylacetate
- CBNumber:
- CB5708211
- Summenformel:
- C10H21O5P
- Molgewicht:
- 252.24
- MOL-Datei:
- 27784-76-5.mol
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tert-Butyl diethylphosphonoacetate Eigenschaften
- Siedepunkt:
- 100-103 °C/1.5 mmHg (lit.)
- Dichte
- 1.074 g/mL at 25 °C (lit.)
- Brechungsindex
- n20/D 1.431(lit.)
- Flammpunkt:
- >230 °F
- storage temp.
- Inert atmosphere,Room Temperature
- Löslichkeit
- Chloroform (Slightly), Ethyl Acetate (Slightly)
- Aggregatzustand
- Liquid
- Wichte
- 1.074
- Farbe
- Clear colorless
- Wasserlöslichkeit
- Not miscible or difficult to mix in water.
- BRN
- 2050126
- InChI
- InChI=1S/C10H21O5P/c1-6-13-16(12,14-7-2)8-9(11)15-10(3,4)5/h6-8H2,1-5H3
- InChIKey
- NFEGNISFSSLEGU-UHFFFAOYSA-N
- SMILES
- C(OC(C)(C)C)(=O)CP(OCC)(OCC)=O
- CAS Datenbank
- 27784-76-5(CAS DataBase Reference)
tert-Butyl diethylphosphonoacetate Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R36/38:Reizt die Augen und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Chemische Eigenschaften
Clear colorless liquid
Verwenden
tert-Butyl diethylphosphonoacetate is used as a reactant for preparation of hydroxymethylated dihydroxyvitamin D3 analogs via Wittig-Horner approach, as potential antitumor agents, synthesis of phosphopeptide mimetic prodrugs targeted to Src homology 2 (SH2) domain of signal transducer and activator of transcription 3 (Stat 3) and bicyclic triaminophosphine-promoted stereoselective synthesis of a,?-unsaturated esters, fluorides, and nitriles from aldehydes and ketones using Wadsworth-Emmons phosphonates
Synthese
Triethyl phosphite (485 g) is warmed up to 90°C under N2 atmosphere in a three-necked round-bottomed flask, and /-butyl bromoacetate (541 g) is added dropwise into the system within 2 h. Then, the mixture is stirred at 90°C for around 4 hours and cooled to room temperature. The obtained mixture is distilled under vacuo to remove compounds with low boiling points, and the residue is collected as a colorless liquid tert-butyl diethylphosphonoacetate in 97 percent yield (680 g).
tert-Butyl diethylphosphonoacetate Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
tert-Butyl diethylphosphonoacetate Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 290)Lieferanten
27784-76-5()Verwandte Suche:
- DIETHYL(2-TERT-BUTOXYCARBONYLMETHYL)PHOSPHONATE
- (DIETHOXYPHOSPHORYL)ACETIC ACID TERT-BUTYL ESTER
- DIETHYL (BOC-METHYL)PHOSPHONATE
- DIETHYLPHOSPHONOACETIC ACID TERT-BUTYL ESTER
- DIETHYL (TERT-BUTOXYCARBONYLMETHYL)PHOSPHONATE
- T-BUTYL DIETHYL PHOSPHONOACETATE
- TERT-BUTYL DIETHYLPHOSPHONOACETATE
- tert-Butyl diethylphosphonoacetate, 98 %
- Tert-Butyl p,p-diethylphosphonoacetate
- ACETIC ACID, 2-(DIETHOXYPHOSPHINYL)-, 1,1-DIMETHYLETHYL ESTER
- Tert-buty diethylphosphonoacetate
- tert-Butyl diethylphosphonoacetate,95%
- Tert-butyl diehylphosphonoacetate
- tert-Butyl diethylph
- (Diethoxyphosphinyl)acetic acid 1,1-dimethylethyl ester
- Diethyl tert-butoxycarbonylmethanephosphonate
- tert-Butyl (diethoxyphosphinyl)acetate
- tert-Butyl diethylphosphonoacetate
- Diethyl (Boc-methyl)phosphonate
Diethyl (tert-Butoxycarbonylmethyl)phosphonate
Diethylphosphonoacetic Acid tert-Butyl Ester
- 3-[(2-methylpropan-2-yl)oxy-oxomethyl]pentan-3-ylphosphonic acid
- Diethyl(2-tert-butoxycarbonylmethyl)phosphonate 98%
- tert-Butyl diethylphosponoacetate
- Tert-butyl diethylphosphonoactate
- tert-Butyl Diethylphosphonoacetate >
- Tert-butyl diethyl phosphonylacetate
- TERT-BUTYL DIETHYLPHOSPHONOACETATE (27784-76-5)
- tert-butyl 2-(diethoxyphosphoryl)acetate
- 1,1-Dimethylethyl 2-(diethoxyphosphinyl)acetate
- ert-butyl2-diethoxyphosphorylacetate
- Diethyl phosphonoyl acetate tert butyl ester
- 27784-76-5
- C2H5O2POCH2CO2CCH33
- Horner-Wadsworth-Emmons Reagents
- Olefination
- Synthetic Reagents
- C-C Bond Formation
- C-C Bond Formation
- Horner-Wadsworth-Emmons Reagents
- Olefination
- 27784-76-5
